MSK Publications Added to Synapse in January 2020

Posted on March 5, 2020 by Jeanine

The Synapse team has already added 484 MSK-authored works (published in 2020) to Synapse, our database of MSK publications and authors.

Highlighted here are three articles that are receiving a high amount of attention online. Combined, they appeared in 166 news outlets and 1,236 tweets. To view the news stories and tweets, follow the links below and click on the colored Altmetric section on the right.

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. Nature Genetics. 2020 January 01; 52(1):56-73.
Effect of a behavioral intervention to increase vegetable consumption on cancer progression among men with early-stage prostate cancer: The MEAL randomized clinical trial. JAMA: Journal of the American Medical Association. 2020 January 14; 323(2):140-148.
B cells and tertiary lymphoid structures promote immunotherapy response. Nature. 2020 January 23; 577(7791):549-555.

Tumor Development Timeline, Vitamin C to Enhance Immunotherapy and More

Posted on March 4, 2020 by Marina

Researchers from EMBL’s European Bioinformatics Institute (EMBL-EBI) and the Francis Crick Institute working within the framework of Pan-Cancer Analysis of Whole Genomes (PCAWG) project, created tumor development timelines for several cancer types including glioblastoma, and colorectal and ovarian adenocarcinoma . Their research established that “the mutations that initiate cancer progression may arise decades before diagnosis”. The study was published in Nature.
Researchers at Cardiff University School of Medicine in Wales reported on a new method to fight a wide range of cancers including prostate, breast, lung and others. The method published in Nature Immunology is based on the power of the immune system; the researchers “used genome-wide CRISPR-Cas9 screening to establish that a T cell receptor (TCR) recognized and killed most human cancer types.” This animal study lays a foundation for further research on humans, which potentially can offer “universal” cancer immunotherapy.
Researchers from Italy were able to increase the effect of immunotherapy by enhancing it with high doses of vitamin C. This animal study was published in Science Translational Medicine.

New Database: Timmerman Report

Posted on February 27, 2020 by Ryan

The Library has added a new database – the Timmerman Report. This is an independently-owned subscription publication that provides timely, in-depth biotech news and analysis. It’s for anyone who seeks to understand new drug development, regulatory issues, business strategies, diagnostics, genomics, and other technologies that are changing medicine.

The Timmerman Report will publish 2-3 stories per week on innovations, emerging trends, and market forces in the form of news, commentary, original features and a podcast. This database requires a login and password, and can be accessed here.

MSK Library Blog

Sharing Research, Resources & News

MSK Publications Added to Synapse in January 2020

Tumor Development Timeline, Vitamin C to Enhance Immunotherapy and More

New Database: Timmerman Report

msklibrary