Tag Archives: clinical trials

MSK is a Reason to Love NYC

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Dr. Luis Diaz Jr., far left, and Dr. Andrea Cercek, second from right, with patients from the trial. Photo by Richard DeWitt.

Dr. Luis Diaz Jr., far left, and Dr. Andrea Cercek, second from right, with patients from the trial. Photo by Richard DeWitt.

Reason #37 to love New York in 2022? Memorial Sloan Kettering Cancer Center.

So says New York Magazine as it celebrates the groundbreaking clinical trial led by Dr. Andrea Cercek and Dr. Luis Diaz Jr. In the small trial, all 14 participants who received six months of immunotherapy for rectal cancer had complete remission without additional treatment. The patients had a specific mismatch repair-deficient tumor mutation, which is thought to occur for 5% to 10% of rectal cancers.

Read more about the trial from MSK’s coverage and the New England Journal of Medicine article.

New eJournal: NEJM Evidence

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MSK Library has subscribed to a new multidisciplinary eJournal, NEJM Evidence. The aim of this new journal is to “focus on providing more context and critical evaluation of the methods and results to support clinical decision-making and does so in a way that respects the time and commitment of the practitioner.”

NEJM Evidence‘s research include clinical trial design, epidemiology studies, first-in-human trials, and meta-analyses.

New eBook – Oncology Clinical Trials: Successful Design, Conduct, and Analysis

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Oncology Clinical Trials: Successful Design, Conduct, and Analysis has been added to the Library’s collection. This second edition contains designs and methods of conducting and analyzing cancer clinical trials, including trials “investigating the safety and efficacy of targeted therapies, immunotherapies, and combination therapies as well as novel radiation therapy modalities.”

This text includes a background and introduction to oncology clinical trials, designing trials, conducting trials, analyzing the results of clinical trials, and special considerations in oncology clinical trials.