New eJournal – JACC: Cardiovascular Imaging

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The Library has subscribed to a new journal, JACC: Cardiovascular Imaging. This journal covers aspects of cardiovascular imaging and includes original clinical research on non-invasive and invasive imaging, techniques including echocardiography, CT, CMR, nuclear, optical imaging, and cine-angiography.  

JACC will appeal to practicing clinicians by highlighting imaging modalities within the “imaging continuum,” helping clinicians navigate through “modality parochialism” to scientifically identify which modality works best in what situation, and to eventually develop “imaging algorithms.”

Pancreatic Cancer: New Findings

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Researchers from the Institute of Cancer Research in London identified a protein, GREM1, essential in regulating pancreatic cancer tumor cells. Their study used two models, a mouse model, and a tumor organoid model. By switching the protein GREM1 on and off, the authors showed that different levels of GREM1 could either produce more aggressive and invasive tumor cells or revert tumor cells to less aggressive forms. While those results are still preliminary, the authors hope their findings could help develop new treatments for pancreatic cancer, which has proven, so far, very difficult to treat. The study was published in Nature.

In a study conducted at the Johns Hopkins Kimmel Cancer Center, the authors show that surveillance programs for people at high risk of developing pancreatic cancer are crucial for effectively treating this type of cancer. “The five-year survival to date of patients with a surveillance-detected pancreatic cancer is 73.3%, and median overall survival is 9.8 years, compared with 1.5 years for patients diagnosed with pancreatic cancer outside surveillance.” The study was published in the Journal of Clinical Oncology.

New eJournal: International Journal of Surgical Pathology

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The International Journal of Surgical Pathology is a recently added journal that offers original research and observations covering all major organ systems, reviews of new techniques and procedures, discussions of controversies in surgical pathology, case reports, and images in pathology. IJSP also features diagnostic pearls, investigations from the forefront of molecular surgical pathology as it applies to surgical pathology, and profiles of tumors and immunomarkers.

Major topics include thyroid tumor pathology, controversial aspects of tumor pathology, soft tissue tumors, immunohistochemical profiles of tumors, genetics and pathology of familial gastric cancer, and critical analysis of image analysis systems in pathology.