Dr. Michel Sadelain and his team along with researchers at UC-San Diego and USC have shown that using mechanogenetics – how physical forces and changes in the mechanical properties of cells and tissues can influence how genes are expressed – to manipulate CAR-T cells to only attack cancer tissues. The researchers found by using ultrasound waves, they could direct certain cells to turn on CAR-T cell gene expression. This research could revolutionize the availability and safety of CAR-T cell treatment by increasing the effectiveness and minimizing the subsequent toxicities of these treatments.
Category Archives: In the News
Do You Know That Bacteria Can Be Turned into Music?
A group of scientists, musicians, engineers, and artists have created Biota Beats, a project that translates human microbiota into hip hop music. The group was originally inspired to start the project for a synthetic biology competition called iGEM in 2016.
MSK Publications Added to Synapse in December 2017
Take a look at these MSK-authored articles, recently published and mentioned in over 50 news stories thus far:
- Research and Development Spending to Bring a Single Cancer Drug to Market and Revenues After Approval. JAMA Intern Med. 2017 Nov 1;177(11):1569-1575. doi: 10.1001/jamainternmed.2017.3601
- Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis. Nat Med. 2017 Nov;23(11):1362-1368. doi: 10.1038/nm.4407
- Adrenergic nerves activate an angio-metabolic switch in prostate cancer. Science. 2017 Oct 20;358(6361):321-326. doi: 10.1126/science.aah5072
To read the stories, click on the Altmetric donut from the links above and go to “News.” Visit this link to see everything added to Synapse in last month.