Author Archives: Marina

PubMed 2.0 is Under Development

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The National Library of Medicine is working on a new interface for PubMed. The new interface will have a more modern look and feel, and will include a variety of new features, such as additional support for mobile devices.

This new interface is currently in beta testing over at PubMed Labs and is publicly available. Users are encouraged to try it and provide their feedback.

Please be aware, since the new interface is still in development, as of now it can’t replace the current PubMed in content and functionality. The National Library of Medicine has announced that not all new/planned features can be found in PubMed Labs yet, but more and more features are being added.

The MSKCC Library is monitoring the progress of these new developments. Once the new PubMed is fully ready for public use, the Library will be offering relevant instruction and assistance.

We hope that the new PubMed will provide an exceptional user experience and support the features users are looking for.

Time Restricted Eating, Circadian Rhythms, and More

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A selection of cancer research in the news this past week…

  • An animal study on breast cancer showed that eating within just an eight-hour window every day could “prevent the development of tumours”. The study’s lead researcher, Dr. Manasi Das, suggested that “this intervention may be effective in breast cancer prevention and therapy”. The study on time restricted eating was formally presented at ENDO 2019 conference (March 23-26, New Orleans).
  • Researchers from Tulane University established that circadian disruption caused by exposure to dim light at night may contribute to the metastatic spread of breast cancer to the bone. This animal study was also presented at ENDO 2019 conference.
  • Also focused on breast cancer, a trial conducted at Marshall University demonstrated that walnut consumption altered gene expressions related to tumor progression and could “decrease breast cancer growth and survival”. The new study on this ongoing research is in press and is due to be published in Nutrition Research. Note: Primary funding for this study “was from the California Walnut Commission to WEH”.
  • Researchers from Mount Sinai Icahn School of Medicine conducted a study that uncovered “how cancer cells with identical genomes can respond differently to the same therapy”. The study published in Nature Communications established the “relationship between mitochondria variability and drug response” which “may lead to more effective targeted cancer treatments”.
  • University of Bradford and University of Surrey, UK researchers discovered that prostate cancer cells “spit out” a protein from their nucleus taken up by other cells, including normal cells, which provokes tumor growth. The study was published in Scientific Reports.
  • A study conducted by researchers from the UK and Spain determined that a protein produced by melanoma cells triggers reprogramming of healthy immune cells to prevent them from attacking cancer cells and to help them survive instead. The study was published in Cell.

Searching on Multiple PubMed IDs

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The PubMed ID (PMID) is one of several standard identifiers in the NCBI system of resources (PubMed, PubMed Central, etc.). You can find a reference in PubMed searching on its PMID number by entering the number in the search box.

If you have a list of PMIDs (created by yourself or supplied by a colleague) and you want to convert it into a list of references — this is easy to do!. Each PMID number can be used as a search term.  Just enter each PMID (by typing or pasting) in the PubMed search box, leaving a space between each number. You don’t need to use a Boolean Operator between each number.

Once you click on the Search button, PubMed converts the numbers into a search strategy by automatically placing an OR between each number behind the scenes and applying the [uid] qualifier to the search string.

This is how the search strategy would look behind the scenes:
30856610 30856515 30856373 30856296 30856208[uid]

PubMed will do the same even if you enter the OR between each PMIDs. Both approaches would work, however you can save time with the method just shared. If you have any questions regarding this tip or would like to learn more about PubMed, don’t hesitate to ASK US!  You can also check out our workshop calendar for an upcoming PubMed session.