Sharing Research, Resources & News
- Research conducted by a group of scientists from different institutions led by the University of Michigan Rogel Cancer Center has identified a key braking mechanism that could potentially halt the runaway growth of many different types of cancer. The scientists achieved a precise understanding, which was lacking in previous research, of how the activity of PP2A, an enzyme produced by the body and capable of halting the tumor growth, is increased by small molecule activators of PP2A (SMAP), specifically, by DT-061 SMAP. This breakthrough discovery can be potentially used in developing new promising treatments. The study is due to be published in Cell.
- Researchers from Francis Crick Institute (London, UK) identified an experimental drug instrumental in preventing cancers from recurrence. The drug. Quisinostat, could stop tumor re-growth after initial treatment in live mice and prevent the expansion of surviving human cancer cells in culture. Quisinostat works by interfering with the cancer cells epigenetic state to stop them from self-renewal. The study has been published in Nature Communications.
- Researchers from the University of Bayreuth (Germany) identified a natural protective mechanism against cancer that can develop as a result of the irregular distribution of genetic information to daughter cells. Their research focuses on the role of enzyme separase in cellular processes. The findings, which offer new approaches for cancer therapy, are published in Nature,
- Researchers from the United States and Europe reported successful implementation of an Artificial Intelligence algorithm for stratifying the risk of indeterminate pulmonary nodules (IPNs). The use of Artificial Intelligence may lead to decreasing invasive procedures and reducing cancer diagnosis delays, which are crucial for timely cancer treatment. The study is due to be published in the American Journal of Respiratory and Critical Care Medicine.