MSK’s Dr. Peter Bach on Drug Economics

Two recent articles in major news outlets feature MSK’s Dr. Peter Bach discussing drug costs.

A Washington Post article considers alternate methods for calculating drug prices, including “value-based pricing.” Dr. Bach comments that such a system would “anchor a drug’s price to its benefit,” but that the benefit would have to be very clearly defined. Later in the article, Dr. Bach states that it is difficult to determine which aspects of drugs should be valued most and thus become factors in both cost and drug development priorities in a value-based pricing system.

A New York Times article takes a historical view of rising drug costs. U.S. drug spending tripled from 1997 to 2007, then plateaued for about six years before rising again. Dr. Bach explains that the more recent price hikes are due in part to a lack of competition for new biologic drugs and quicker FDA approvals for new, expensive pharmaceuticals.

FDA Moves to Restrict Vaping Products Amidst Growing Health Concerns

On November 9, 2018 the FDA announced it will begin restricting the sales of flavored, cartridge-based vaping products such as Juul to only tobacco shops and vape shops in an attempt to keep them out of the hands of children and teenagers. But does using cartridge-based vaping products cause cancer? The short answer is, it’s too early to tell.

A recent study published in the journal Pediatrics examined teens who use e-cigarettes and analyzed urine samples to find out what chemicals enter the body. The researchers found that e-cigarette users were exposed to volatile organic compounds such as propylene oxide and acrylamide, which are carcinogenic. Another study found that e-cigarette aerosol causes DNA damage in mice. Ultimately, the long-term health effects of vaping remain unknown and are ripe for further study.  

Open Surgery a Better Option for Cervical Cancer

A study published in the New England Journal of Medicine last week compared minimally invasive and open surgeries for early stage cervical cancer. This prospective randomized trial of 631 participants at 33 medical centers found that patients who had open surgery had higher disease-free survival rates (96.5% at 4.5 years) than those who had minimally invasive surgery (86% at 4.5 years). In reporting the study, the New York Times spoke to numerous gynecologic oncologists, many of whom had heard about the results prior to publication and had already begun changing their approaches to cervical cancer treatment. MSK’s Dr. Ginger Gardner said that the hospital is reviewing its surgical results and making case-by-case surgical decisions in consultation with patients.