How To Search for a Phrase in PubMed

Searching for phrases in PubMed can be an exercise in frustration. To understand why, we need to look at how PubMed interprets your search, a process that is now described in detail in a new training module from the National Library of Medicine.

When you enter a phrase into PubMed without using quotation marks, the database does several things:

  1. Looks for the phrase as a subject heading, or MeSH, term. Subject headings have been preselected by the database and are assigned to each citation on a topic.
  2. Breaks apart the phrase and looks for each word separately.
  3. Looks for the phrase, if recognized.
A graphic describing how PubMed Searches for a phrase.

How PubMed searches for a phrase. From the National Library of Medicine.

Sometimes, this process brings back the results you need. But it can also lead to search results that do not match your topic.

What happens when you search using quotation marks?

  • Instead of looking for matching subject headings, PubMed checks for the phrase in its phrase index, a list drawn from the literature included in the database.
  • Not every phrase is included in the phrase index. If your phrase is not found, PubMed may ignore your quotation marks and follow the search steps above, bringing in irrelevant results.
  • You can see how many results include your phrase from the advanced search page. Start typing your term, then click “Show index” to the right of the search box.
A screenshot showing how to check if a phrase is included in PubMed's phrase index.

Use the “Check index” button on the advanced search page to see if your phrase is included in PubMed’s Phrase index. From the National Library of Medicine.

Fortunately, there is a workaround if your phrase is not found. You can recommend the addition of phrases to PubMed. You can try searching for the phrase in different databases,  most of which are much more user-friendly when phrase searching. You can also try searching for the phrase in PubMed using adjacency.

For example, “Adult Non-Verbal Pain Scale” is not a phrase PubMed recognizes. Have PubMed look for the phrase with all words next to each other, in any order, by telling it to look in the title and abstract fields (tiab) with the words adjacent to each other (:~0):

The PubMed advanced search page showing the difference in results using quotation marks and proximity searching for a phrase.

Using proximity searching ([tiab:~0]) when a phrase is not included in PubMed’s phrase index can lead to more focused results compared to using quotation marks alone.

For more search help, or to request a literature search, contact the Library.

Speed Up Your Searching with LibKey Nomad

LibKey Nomad is a browser extension (available for Firefox, Chrome, Edge, Safari, and more!) that provides seamless one-click access to full-text MSK library resources from a wide variety of databases and journals!

Simply install the extension in your preferred browser; during installation you will be asked to select your organization – search and select Memorial Sloan Kettering Library.

How LibKey Nomad Works

Once you’ve downloaded and installed the LibKey Nomad browser extension, a new icon will appear at the bottom of the page when searching on various databases, websites, and journal platforms.

Note: Depending on the browser and/or the settings you have set, you may need to tell LibKey Nomad to allow access to a website, which you can usually set to always allow access to a specific site (eg. PubMed’s website). The browser extension should be visible in the top of your browser and will look like the green LibKey icon above.

Once the page loads, the browser extension will identify the citation(s) and, based on our library’s collection, will guide to access the full-text of each citation on the page.

If PDF full-text is available, a single-click Download PDF button will appear below the citation. If additional authentication is required you will be prompted to sign in via the MSK single sign-on. In most cases the PDF will be coming directly from the publisher or a supporting platform, however in some cases it may find the full-text through PubMed Central (PMC) or a institutional repository.

LibKey Nomad access buttons

  • Download PDF: In a single click the user should be able to either view the PDF in their browser or be prompted to download the PDF to their computer.
  • Article Link: Similar to the PDF full-text, this option appears when either the full-text is only available as HTML, or if a PDF is available but an additional click is required once arriving at the publisher’s website
  • Manuscript PDF: This option appears if the article has been located in a repository as an Accepted Manuscript; while this manuscript has been peer-reviewed and accepted for publication, it is likely not formatted for publication yet and may simply be a Word document converted to PDF
  • Manuscript Link: Like the Manuscript PDF button, this will appear if the manuscript is available, but not in PDF format (HTML, Word document, etc.)
  • Access Options: Lastly, if full-text cannot be located immediately, this button will bring you to the MSK Library catalog where you can submit a request through our document delivery service[
  • View Complete Issue [BrowZine]: Integration with BrowZine in certain databases will provide a link to the entire journal issue in BrowZine for a selected citation

Where can I use LibKey Nomad?

Third Iron is continually adding new platforms and publishers to their list of places with LibKey Nomad integration. Currently the extension is supported in a number of databases and websites, as well as a wide range of major journal and eBook publishers.

Library databases with LibKey Nomad Integration:

publishers/Platforms with libkey nomad integration

Note: These publisher sites and platforms represent the discovery starting points but do not represent the coverage of content which extends to *all* eBooks and journals within a libraries collection!  

What’s the difference between libkey nomad and Browzine?

Both LibKey Nomad and BrowZine are produced by Third Iron and they work in conjunction to provide access electronic access to journal articles. LibKey Nomad is a browser extension to identify full-text articles on the web, while BrowZine is a platform to browse and read articles. In certain databases a citation may be able to provide both a link to download the PDF as well as a link to view the entire journal issue that the citation is found in.

For more information about LibKey Nomad

LibKey Nomad tutorial video:

ThirdIron: LibKey Nomad browser extension delivers one-click article access (1:58 min)

2025 MeSH Update and PubMed Year-End Activities

At the end of each year, the National Library of Medicine (NLM) produces their annual updates to PubMed’s MeSH (Medical Subject Headings). These changes are made at every level of the MeSH infrastructure, including descriptors (headings or terms), qualifiers (subheadings), and supplementary concepts, and are made in response to changes in scientific discovery, taxonomy, ethical considerations, and published literature. The National Library of Medicine describes the necessity of these changes as this: “In biomedicine and related areas, new concepts are constantly emerging, old concepts are in a state of flux and terminology and usage are modified accordingly. To accommodate these changes, descriptors must be added to, changed or deleted from MeSH with adjustments in the related hierarchies, the Tree Structures.”

Types of MeSH Changes

  • Added Terms — brand new terms added, either as MeSH headings or Supplementary Concepts that currently do not warrant a full heading
  • Modified Terms — MeSH concepts that were changed (either name or hierarchical location), also referred to the the “Preferred Term
  • Replaced Terms — Descriptors or Supplementary concept terms are replaced by another term; this can include Supplementary Concepts upgraded to Descriptors as well as merged terms
  • Merged Terms — Multiple Descriptor or Supplementary concept terms combined under a single concept term
  • Combined Terms — Descriptor and Qualifier (subheading) combination made into a new separate concept
  • Deleted Terms — Descriptor or Supplementary concept terms removed, due to either being combined, upgraded, or renamed

What’s New in 2025

Artificial Intelligence

The 2025 Annual MeSH Update includes a variety of important and much-needed changes. One of the biggest and most needed expansions in the 2025 update is to the Artificial Intelligence concept, including dozens of new MeSH Descriptors found within the broader concept, including:

Publication types

Several changes were made to publication types for MeSH 2025, including two new publication types:

Note: The NLM has made an exception to their general rule of not retroactively indexing; so just as they did in 2019 when “Systematic Reviews” became a separate publication type, citations will be retroactively updated to reflect these two new publication types.

The Network Meta-Analysis publication type was previously a Descriptor (MeSH Heading); thus for existing citations, the Descriptor term (“Network Meta-Analysis”[MeSH]) will be replaced with either the “Network Meta-Analysis”[Publication Type] OR “Network Meta-Analysis as Topic”[Mesh] as appropriate. This is an important change, as it extends the scope of indexing the publication type back to the introduction of the original term in 2017.

The “Scoping Review”[Publication Type] will replace either the “Review”[Publication Type] or “Systematic Review”[Publication Type] on appropriate citations extending back to 2020, the first year this term appears in MEDLINE. Additionally, “Scoping Review as Topic”[Mesh] has been expanded from the “Review as a Topic”[Mesh] term.

Additionally, NLM will discontinue indexing following Publication Type terms:

Note: As with previously discontinued Publication Types, which include “Government Publication,” “Newspaper Article,” “Overall,” and “Scientific Integrity Review,” these Publication Types will continue to exist in MeSH, appear on existing citations, and be searchable in PubMed. However, they will no longer be applied to new citations.

How Does this Impact Searching?

Since there are so many changes to MeSH terms and structure, if you save search strategies or search alerts, or want to rerun a search that was previously conducted (such as from a systematic review), these changes may impact if and how your search strategy functions. Below are some steps to take to ensure that your search strategy is not only viable but also the best reflection of the current database.

  1. Check search viability — Run your search in PubMed and go to Advanced Search and check if there are issues being highlighted in the Details section. Terms that were removed or modified (name changed, upgraded, merged, etc.) will likely be in red. If your search is suddenly retrieving no results, this also could be the cause.
  2. Identify relevant new terms — Refer to the New MeSH Descriptors for 2025 list to see if there are any relevant terms that were added for 2025 that may make your search strategy more robust or specific.
  3. Identify replaced terms — Refer to the MeSH 2025 – Replace Report to identify any terms that were replaced by another term, upgraded to Descriptors, or consolidated with another term.
  4. Review publication types — Refer to the Annual MeSH Processing for 2025 NLM Bulletin for changes to publication types

If you have searches saved in your My NCBI account and/or you are getting PubMed e-mail alerts, or if you need to update your Systematic Review based on your previous search strategy, you may want to consult a Research Informationist to ensure your saved searches are not affected by the annual changes in the MeSH terminology. Don’t hesitate to ASK US!

Important Note from NLM Regarding Reindexing

Typically, the NLM does not retroactively re-index MEDLINE citations with new MeSH heading concepts. Therefore, searching PubMed for a new MeSH term tagged with [mh] or [majr] effectively limits retrieval to citations indexed after the term was introduced. Searchers may consult the MeSH database to see the previous indexing terms most likely used for a particular concept before the new MeSH heading was introduced. For terms without previous indexing information, consider the next broader term(s) in the MeSH hierarchy. or more searching guidance, see the on-demand class MeSH Changes and PubMed Searching.