- Researchers from the UC Davis Comprehensive Cancer Center identified a new way to trigger programmed cell death related to CD95 receptors. These protein receptors, also called Fas, are located on cell membranes and are instrumental in causing cell self-destruction. The research on new ways to trigger programmed cell death of tumor cells can lead to improved cancer treatments. The study was published in Cell Death & Differentiation.
- In a preclinical study, researchers developed a new treatment for medulloblastoma, an aggressive brain cancer affecting mostly children. Researchers administered drug-carrying nanoparticles directly into the cerebrospinal fluid (CSF), thus overcoming existing challenges in delivering drugs in the CSF. The study was published in Science Translational Medicine.
- U.S. researchers discovered the mechanism of how breast cancer cells may metastasize. The researchers showed that a motor protein, dynein, facilitated the movement of cancer cells in soft tissue models. This research paves the way for discovering new clinical targets against metastasis and has great potential for cancer treatment. The study was published in Advanced Science.
- An international group of researchers is offering a “noninvasive alternative to surgery, chemotherapy and radiation treatments for cancer.” The U.S. Food and Drug Administration (FDA) has approved using targeted ultrasound waves, a technology called histotripsy, to fight cancer. The most recent study related to this research was published in Frontiers in Immunology.