A new study by MSK’s Dr. Neil Iyengar and colleagues published in JAMA Oncology finds that women with normal BMIs but high levels of overall body fat are at an increased risk for invasive breast cancer. The cohort study followed 3,460 postmenopausal women for a median 16.4 years. Researchers measured body fat using Dual-energy X-ray absorptiometry five times throughout the course of the study. They concluded that for each five kilogram increase in trunk fat, women had a 56% increase in risk of developing estrogen-receptor (ER) positive breast cancers, even when BMI remained in the healthy range.

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