We at the MSK Library are often called upon to help our researchers with searches. Whether it’s a literature review or a systematic review depends on the needs of the patron, but what is the difference between these two and when are they needed? Both systematic and literature (or comprehensive) reviews are a gathering of available information on a certain subject. The difference comes in the depth of the research and the reporting of the conclusions. Let’s take a look.

A literature or comprehensive review brings together information on a topic in order to provide an overview of the available literature on a certain subject. Research materials are gathered through searching one or more databases and qualitatively brought together in the review. Literature reviews can be the first step in perusing a topic for a further study to get an idea of the current state of the science available but they can also be their own publication. Complete our Literature Search form if you would like us to find information on a review or other project you are working in.

Systematic reviews look at a topic more in depth using a scientific method. By looking at not only the available literature, but also theses/dissertations, abstracts/conference proceedings, and other grey literature sources, systematic reviews seek to be all-encompassing in showing results on a topic. To complete a systematic review, a team of researchers select a clinical question to be answered and specify eligibility criteria for their resources before synthesizing the information to answer their question. Multiple databases are searched in order to find every possible article on the topic. Not only are the results of the searches presented, but the search strategy, assessments and interpretations of research are also included in this form of review. Here at MSK, we use the PRISMA Statement to provide a helpful structure when working on systematic reviews. Take a look at our Systematic Review LibGuide to learn more about this investigation into the literature.