For the past two decades, research has swelled around the idea of liquid biopsies, where information about cancer diagnoses to prognosis and drug responses, can be found from a sample of the patient’s blood. At this year’s American Association for Cancer Research (AACR) meeting, there were over 130 presentations, posters, and panels on these innovations. But it all likely wouldn’t be without an amazing team of researchers now led by Dr. Luis Diaz. For the past 25 years they have collaborated on research to take liquid biopsies from an idea to reality. They were honored at this year’s AACR where they were awarded the 2017 AACR Team Science Award, which acknowledges the work and importance of interdisciplinary teams in cancer research.
Author Archives: Lindsay
Former Transplant Patient Brings Experience to MSK’s BMT Team
In April 1990, Eric Davis was just two years old and diagnosed with aplastic anemia, a disease that would eventually require a bone marrow transplant for him to stay alive. When none of his family were matches, the family began raising the $100,000 required to find an unrelated donor. Finally in 2004, when his disease was no longer able to be controlled by the drugs the doctors prescribed, a donor was found in Germany. The transplant essentially cured Eric and he was able to thrive, later earning a degree in biology. He also found his way to New York City in 2011, working in a research lab at Memorial Sloan Kettering (MSK). When a position opened up to manage the Unrelated Donor Program at MSK, he jumped at the chance to be able to help patients like himself.
Patient Safety Pubs, MSK on CBS, Team Ginger, and a Sunscreen Study
In honor of Patient Safety Week, here’s a compilation of recent publications by MSK authors focusing on patient safety.
Last Sunday, MSK was featured on CBS Sunday Morning in a segment about immunotherapy clinical trials. Young Ezzy Pineda is 12 years old and was diagnosed with leukemia when she was nine. After multiple failed rounds of chemotherapy, she was enrolled in a CAR-T clinical trial at MSK under Dr. Kevin Curran, a pediatric oncologist. While Ezzy is still one of the promising exceptions, found to be cancer-free six weeks after her CAR-T infusion, it gives doctors and patients with incurable cancers everywhere hope. According to the NCI’s Dr. Rosenberg, considered to be the father of immunotherapy, “If you look at all cancer patients, perhaps 10 percent can be helped by immunotherapy today…but it’s getting better every day.”
Matt Seconi has been pedaling for Team Ginger since 2014, shortly after his then girlfriend Kelly Knab was diagnosed with pancreatic neuroendocrine tumors. While she was undergoing treatment they sought ways to be involved in the cancer community. It was February 2014 when the pair participated in their first Cycle for Survival event in San Francisco, heading a team in honor of Kelly aptly named Team Ginger since Kelly was a redhead. Two months later they brought Team Ginger to ride in Times Square. Matt and Kelly were engaged in December 2014, only days before Kelly passed away on January 2, 2015. She was 28 years old. Seconi used his grief to pedal even harder, back at it for the 2015 events. Since Kelly’s passing, Seconi has participated in 17 rides across the country and raised $660,000 for cancer research.
A recent study by Dr. Steven Wang, a dermatologist at MSK who works with melanoma patients every day, looked at 20 of the best-selling sunscreen products in the United States marketed as 15 to 100 SPF and broad-spectrum. They tested the products based on critical wave length requirement in the US and the UVA protection factor test in Europe. All but one product met the US standard, however nine products failed the EU standard, including eight with an SPF of 50+. Part of the issue is that there are only 17 active ingredients are approved for use in the US, and significantly fewer long-range UVA filters available. Wang argues that the US needs to add new filters into formulation to improve protection, “We’re always looking for new ways to improve protection by adding inactive ingredients with a better film-forming technology.”