Return to Today's science sparks archives
Click the tweet icon above each article title to share it on Twitter.
|
Conventional transbronchial forceps biopsy specimens (A) are smaller and usually show more procedural artifacts than transbronchial cryobiopsy specimens (B)
|
 |
|
Fig 2. RECIST 1.1 and iRECIST: an example of assessment.
|
|
|
Fig 4. Atomistic MD simulations of the TMD of ADAM17 and Rhbdf2 TMD1.
|
|
|
Fig 1. Pathology images.
|
|
|
The map of the integrative vector pIMBT1 suitable for the genus Amycolatopsis.
|
|
|
Fig 2. TRAC-CAR T cells display reduced constitutive signalling and antigen-induced differentiation.
|
|
|
Fig 1. Participant flow diagram.
|
|
|
Fig 4. Incomplete and individualized recovery of the human microbiota after vancomycin withdrawal.
|
|
|
Fig 1. Different bispecific antibody formats.
|
|
|
Fig 1. The RAS/MAPK pathway and RASopathies.
|
|
|
Fig 4. Concurrent somatic alterations in validation data set.
|
|
|
Fig 5. Somatic aberrations in the PI3K pathway dysregulate cancer-specific TFs.
|
|
|
Fig 1. Kaplan–Meier analysis of associations of the CD8 EM1 (A) and EMRA (B) T-cell compartments with OS at baseline (n = 137 for both analyses).
|
|
|
Fig 2. Multimodal imaging of Case 2 showing bilateral choroidal infiltration with associated serous retinal detachment (SRD) owing to Erdheim-Chester disease and the response to systemic treatment with the subsequent development of a secondary choroidal neovascularization.
|
|
|
Fig 2. Schematic illustrations of nanomaterials platforms, which are approved, in preclinical development, or in clinical trials.
|
|
|
Fig 5. Systemic toxicity profiles of FiBYL719 nanoparticles.
|
|
|
Fig 1. ATM and ATR are activated by DNA damage as well as DNA replication stress.
|
|
|
Fig 3. Topical tacrolimus decreases fibrosis in lymphedema.
|
|
|
Fig 7. Model for putative PS-induced enhancement of ACD11.
|
|
|
Fig 1. Melanomas become differentiated after dissemination to secondary sites.
|
|
|
Fig 2. Circos plot showing called mutations in the ZMEL1 line.
|
|
|
Fig 1. The estimated factor loadings onto the six factors after the Varimax rotation was performed.
|
|
|
Fig 1. Signaling pathways in uveal melanoma.
|
|
|
Nat Commun. 2017 Jan 31;8:14248.
|
|
|
Fig 1. Genomic context and primary structure of Runella HD-Pnk.
|
|
|
Fig 1. Splicing catalysis, the spliceosome assembly pathway, and mechanisms of SS selection.
|
|
|
Fig 1. Pathways and Current Drugs in Metastatic Renal-Cell Carcinoma.
|
|
|
Fig 3. FGFR1 overexpression attenuates the antiproliferative action of alpelisib.
|
|
|
Fig 3. Examples of mutational 3D clusters in tumor suppressor genes.
|
|
|
Fig 2. Effects of the different Rep constructs on HSV-1 and AAV2 DNA replication.
|
|
|
Fig 4. Correlation between mtDNA copy number and mtRNA expression.
|
|
|
Fig 1. A similar 3′ flap DNA structure is generated during the L1 insertion process (TPRT) and the NER pathway.
|
|
|
Fig 1. Anterior and posterior (A/P) image count and associated automated BSI values in repeated bone scans of patients with same scanning speeds (Grp1) (A) and in repeated bone scans of patients with twice scanning speed of original scan (Grp2) (B).
|
|
|
Fig 1. Flowchart of the prediction algorithm.
|
|
|
Fig 3. Anteroposterior (A) and lateral (B) postoperative radiographs demonstrating anterior and posterior instrumented fixation.
|
|
|
Fig 1. A cartoon depicting the four basic steps of the pretargeted.
|
|
|
Fig 1. AhR negatively regulates CSR ex vivo.
|
|
|
Fig 4. In vivo quantitative evaluation of GW3965-loaded nanoparticles.
|
|
|
Fig 2. Heatmap summarizing the FDRs of 485 significant pathways and unsupervised hierarchical clustering of morphological features.
|
|
|
Fig 4. Snapshot from Molecular Dynamics Simulation of γ-Secretase Complex with Inhibitor after 85 ns.
|
|
|
Fig 2. Typical comprehensive whole-body magnetic resonance imaging protocol depicting extensive metastatic bone disease.
|
|
|
Fig 1. International Spine Radiosurgery Consortium anatomic classification system for consensus target volumes for spine radiosurgery (28).
|
|
|
Fig 1. Radiomics analysis workflow. Radiomics-based analysis starts with segmentation of the structure(s) of interest, in this case, bladder cancer. Various texture features including Haralick textures are generated. A machine-learning classifier is trained using features generated from several images. Classification of various measures is then performed on never-seen-before images.
|
|
|
Fig 3. Causes of death in the entire population (A) and according to the HCT-CI (B).
|
|
|
Fig 1. Percentage of patients with each grade 3-5 nonhematologic toxicity group.
|
|
|
Fig 2. Suggestion for the prostatic fossa clinical target volume in adjuvant or salvage radiotherapy after a radical prostatectomy.
|
|
|
Fig 1. Allo-HCT outcomes comparing 7/8 HLA high-resolution matched patients based on HLA-C encoded KIR ligand status (ie, C1, C2) and HLA match or mismatch.
|
|
|
Fig 2. Adrenocortical carcinoma, adrenal gland, ferret.
|
|
|
Fig 2. Evidence-based variant categorization.
|
|
|
Fig 1. CT scan reveals intrahepatic cholangiocarcinoma.
|
|
|
Fig 3. Projection of the most important variables and interactions in the ePCR model.
|
|
|
Graphical Abstract
|
|
|
Fig 1. The key role played by the thymus in T cell reconstitution after allo-HCT.
|
|
|
Fig 4. CT post-contrast appearance of a G2 pNET.
|
|
|
Fig 10. Schematic of the one-step (A) and SPAAC-mediated two-step (B) approaches to the bioconjugation of antibodies using transglutaminase (TGase).
|
|
|
Fig 3. Direct repression of the elav 3′ UTR via the miRNA pathway and miR-279/996.
|
|
|
Fig 1. Generation and validation of a stable cell line overexpressing ornithine decarboxylase (ODC).
|
|
|
Fig 1. Bethesda category III: atypical follicular lesion of undetermined significance.
|
|
|
Fig 1. Geographic stratification for the British Columbia Telehealth Trial with example Block 1 configuration in Northern Health Region.
|
|
|
Steve Gschmeissner/Science Photo Library
|
|
