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Fig 3. Effects of benzyl-4-piperidone compounds on growth and apoptosis in Ewing sarcoma preclinical models.
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Fig 4. Interfacial mutants on BNRF1 exhibit reduced subnuclear co-localization with DAXX.
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Fig 1. Modeling oncogenic chromosomal rearrangements by genome editing.
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Fig 4. PtdIns(3)P binding to PX domain of SGK3 promotes phosphorylation and activation by PDK1.
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Differences in the diagnosis methods and treatment methods of traditional Chinese medicine and Western Medicine.
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Fig 1. p28 Mechanism of antitumor action.
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Fig 1. Structure of MORC3 ATPase-CW cassette in complex with AMPPNP and H3K4me3 peptide.
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Fig 1. SAR405838 mode of action and determination of VAF threshold for TP53 mutations.
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Fig 9. Mixed acinar ductal carcinoma.
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Fig 2. Schematics of (A) the chemoenzymatic synthesis of sshuA33-PEG12-TCO and (B) the bioorthogonal approach to pretargeted PET imaging.
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Fig 4. Two pathways for DNA joint molecule (JM) processing are regulated by phosphorylation and SUMOylation.
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Fig 1. Structure-guided mutagenesis of SmG.
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Fig 1. Workflow of tumor–germline sequencing.
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Fig 1. A fateful decision.
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Fig 2. Example of hemithoracic pleural intensity-modulated radiation therapy (IMRT) in a patient with (A) a resected and (B) an unresectable tumor.
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Fig 5. Mature human T-cells expressing a third-generation chimeric antigen receptor (CAR) against CD123, or CD123 CAR and inducible caspase 9 (iCasp9) in combination are functional in vitro.
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Fig 4. Transient Activation-Induced Increase in H3K27me3 at Foxp3-Bound Sites.
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Fig 2. Protein–protein interaction network revealed that proteins indicative of platinum response were significantly enriched in Ran-GTPase binding, ATP synthesis pathways, and regulation mechanisms of the cell cycle.
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Fig 3. Drug-resistance mutations in patients whose central nervous system (CNS) disease progresses during kinase inhibitor therapy.
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Fig 1. CHEK2*1100delC frequency rates per country in legend are shown with 95% confidence intervals and were calculated using a modification of the empirical Bayes approach proposed by Clayton and Kaldor, as described in the methods.
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Fig 3. An example study as a model of combining midostaurin and alloHCT.
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Fig 1. Activity of 14 and the Rv2887 mutations identified in 14-resistant Mtb clones.
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Fig 10. The WT virus dominates in coinfected animals.
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Fig 5. Schematic model of a lipidic pore formed by Bak homodimers.
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Fig 1. Brain MRI with expansile, high T2 signal tumor in the right medial temporal lobe, optic chiasm, optic tracts, hypothalamus, and right parahippocampal region as well as abnormal enhancement in the right medial inferior temporal lobe and right inferior frontal lobe.
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Fig 1. Digitalized prostate histopathology.
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Fig 1. Waterfall plot of 38 evaluable patients (per protocol population) treated with entinostat.
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Fig 2. Murine liver sinusoidal endothelium accumulated fCNT in vivo.
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Fig 4. Mixed epithelial carcinoma.
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Fig 2. Proportion of patients with hyponatremia, by hyponatremia severity and cancer type.
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Fig 6. Network of Proteins Associated with Docetaxel Perturbation of the Cell Cycle.
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Fig 3. This lung shows centrilobular emphysema with dropout of alveolar walls surrounding the bronchiole (hematoxylin and eosin stain, original magnification ×4).
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Fig 8. 6 MV IMRT head and neck.
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Fig 4. Blocking KIR3DL1-h interaction with Bw4-80I rescues natural killer cells (NK cells) from inhibition.
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Fig 5. Structure of the N-terminal domain of Ltn1.
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Fig 3. Hematoxylin and eosin stain at 4× (A) and 20× (B) magnification.
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Fig 1. A paradigm switch in T cell therapy.
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Fig 2. Molecular subsets of LCNEC. A, OncoPrint depicting coalterations in selected genes in LCNEC with presence or absence of RB1+TP53 coalteration defining the major SCLC-like and NSCLC-like subsets, respectively, and MEN1 mutations (mut) and low total mutation burden defining carcinoid-like subset.
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Fig 1. Repertoires of somatic mutations, gene copy number alterations, and mutational signatures in sporadic synchronous endometrioid endometrial carcinomas (EECs) and endometrioid ovarian carcinomas (EOCs).
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Fig 1. Best percentage change from baseline in sum of the longest diameters of target lesions by PD-L1 TPS.
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Fig 2. Systematic Analysis of 166 TFs and 1,309 Drug Perturbation Experiments Identifies Approximately 38,000 Candidate TF-Drug Pairs.
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Fig 2. Strategies for personalized precision immunotherapy.
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Fig 1. Distribution of PMTB oncologic diagnoses.
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Fig 2. Fkh1 interacted with Mph1 through the FHA domain.
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Fig 5. 5-FU Alters Overflow Metabolism In Vivo, and the End Products Can Be Measured in Serum.
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Fig 2. Genetic structure of mcr-1-harboring elements in selected plasmids.
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Fig 3. Tertiary structure of Msm0858 and comparison to mammalian p97.
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Fig 3. Initial changes and resolution of magnetic resonance imaging findings during treatment with nivolumab.
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Fig 1. Next-generation sequencing for clinical infectious disease diagnostics.
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Fig 1. Second generation CAR structure.
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Fig 1. Polypodium leucotomos (PL) extract’s anti-UV effects.
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Fig 1. Fosbretabulin mechanism of action.
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Fig 2. Detected mosaic events on the X chromosome.
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Fig 6. Features of Loqs-Sensitive miRNAs.
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Fig 1. In this figure, part of the MET gene is depicted on the left in A. This portion of the gene includes exons 13, 14, and 15, and introns 13 and 14. DNA is transcribed into pre-mRNA, and introns are spliced out (orange triangles) by normal splicing mechanisms.
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Fig 5. The region encompassing rs55705857 acts as a MYC enhancer and rs55705857-G allele increases this activity.
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Fig 1. Approach and implications to rating the quality of evidence and strength of recommendations using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology (unrestricted use of this figure granted by the US GRADE Network).
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Fig 1. Methodology for application of exclusion criteria. Abbreviations: BSI, bloodstream infection; E. faecium, Enterococcus faecium.
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Fig 3. ADT did not alter the plaque burden but induced plaque necrosis in leuprolide treated mice.
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Fig 1. Recurrent LM along a prior surgical scar, 7 years following initial treatment. The initial lesion was microinvasive with a Breslow depth of 0.1 mm. The recurrence had a depth of 0.8 mm.
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Fig 1. Granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor β chain (GM-CSFRβ) signaling is critical for survival, fungal clearance, and lung integrity during Aspergillus fumigatus challenge.
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