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Fig 1a. Late PAR pairing during male meiosis.
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Fig 1. CALGB trial 79809 schema.
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Fig 2a. The MRE11 complex consists of a globular domain and extended coiled-coils.
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Fig 2b. PAR-3 and its inhibitors in the C. elegans zygote and early embryo.
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Fig 6. Recipient-derived macrophages express the lymphatic endothelial cell marker LYVE-1 after tissue transfer.
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Fig 2. MDS plots of pre-TBI samples using the ex vivo gene signature.
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Fig 4. MiTF/TFE family translocation-associated carcinoma.
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Fig 4. SOX7 and SOX17 are detected in PrE derivatives at E5.5 postimplantation stage.
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Fig 5. Anti-CD47 antibody eliminates ALL engraftment in the PB and BM. (D)BM sections from hematoxylin and eosin (H&E) staining (top) and immunohistochemical human CD45 staining (bottom) are shown from representative mice engrafted with B-ALL posttreatment.
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Fig 2. Comparison of CD8+ T cell and NK cell differentiation and memory generation following viral infection.
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Fig S8. Working Model for RNA Exosome-Dependent AID Activity on Transcribed Duplex DNA Substrates.
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Fig 1. Tumor heterogeneity: crosstalk between tumor cells and nontumor cells.
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Fig 1. Suspicious right chest wall mass.
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Fig 1. Probability of local recurrence in patients with recurrent or persistent neuroblastoma after re-resection and IORT.
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Fig 2. Adenocarcinoma infiltrating among lower uterine segment glands (top right) and mucinous glands (center). Some observers considered this to represent endocervical involvement by tumor whereas other observers did not.
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Fig 2. Three-year recurrence-free survival of 126 patients followed by NBI cystoscopy; 78 patients had tumour recurrence; median (95% CI) recurrence-free survival time was 29 (26–32) months.
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Fig 6b. Jurkat T cells were transiently-transfected as in A, with the exception that cells were additionally cotransfected with a plasmid encoding CXCR4-WT-YFP (green).
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Fig 6ab. Correlation of transcript expression with the pattern of intragenic methylation in M091 cells.
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Fig 3. The first PET/CT (A) shows only mild 18F-FDG uptake in the thoracic aorta wall (arrows). In a repeat examination (B), performed 70 days later, the vascular uptake is much more intense (arrows) and sites of 18F-FDG accumulation are also seen in brown fat tissue.
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Fig 7. Model for Swi6 regulation of centromere replication.
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Fig 1. Primary diffuse large B-cell lymphoma of the CNS in a 12-year-old patient.
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Fig 2a. The amino acid sequence of EcoPrrC is aligned to sequences of the NmePrrC, SmuPrrC, and XcaPrrC proteins. Positions of side-chain identify/similarity in all four proteins are indicated by a filled black circle above the alignment. The conserved peptide motifs of the N-terminal NTPase domain are demarcated by brackets. The 54 amino acids targeted in the alanine scan are highlighted.
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Fig 1. Visualization of the protein embedding.
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Fig 1. Treatment algorithm for the oncology team and/or
general gynecologist for vaginal health promotion in female
cancer survivors.
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Fig 5a. Surface Representation of Combined Effect of Dosage and Antigen Density on Therapeutic Ratio.
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Fig 2b. Average gene density as a function of copy number.
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Fig 1. Risk of MPM on head and neck and other body sites.
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The WHO Nomenclature Committee for Factors of the HLA System met following the 14th International HLA and Immunogenetics Workshop in Melbourne, Australia in December 2005 and Buzios, Brazil during the 15th International HLA and Immunogenetics Workshop in September 2008. This report documents the additions and revisions to the nomenclature of HLA specificities following the principles established in previous reports.
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Fig 1a. Kaplan–Meier Curves for Overall Survival and Progression-free Survival in the Intention-to-Treat Population.
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Fig 4. Single sample GSEA scores of GBM subtypes show a relation to specific cell types.
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Supp Fig 1b. Model of the effects of RAF inhibitors in the presence of wild-type BRAF.
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Fig 1. IDH1 R132 and IDH2 R172 Are Analogous Residues that Both Interact with the beta-Carboxyl of Isocitrate.
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Fig 6. Risks of a disease-free survival event by linear recurrence score, treatment, and number of positive nodes, for 10-year timepoints.
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Fig 3b. Antitumor Response in Each of the 32 Patients in the Extension Cohort.
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Fig 1. Representative histopathologic changes associated with fatal pandemic influenza A/H1N1 infection.
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Fig 1h. Binding of NF-κB family member c-Rel but not p65 to the CD28RE-like element at CNS3.
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Fig 1. This is a graphic representation of the adenoma-carcinoma sequence in the microsimulation screening analysis (MISCAN-Colon) model and potential interventions that affect the natural history of disease.
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Fig 1a. HeLa S3 cells were SILAC-labeled with three different isotopic forms of arginine and lysine.
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Fig 4c. Bright-field imaging and haematoxylin/eosin staining (H&E) of lungs isolated from mice that received an orthotopic injection of 4T1 cells infected with the miR-9 sponge or control sponge, at 4 weeks after transplantation.
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Fig 3. Integration of Environmental Cues by Proinflammatory Effector T Cells and Anti-inflammatory Treg Cells in the GutCytokine microenvironment impacted by the gut microbiota promotes Stat3 phosphorylation, which in turn induces differentiation of activated T cells into Th17 effector cells.
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Fig 2i. Tumors were dissected and fresh frozen in optimum cutting temperature solution, cut, and stained for DAPI (blue), CD31 (red), and CD4 (green).
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Fig 1b. Sagittal view of PET scan after 4 weeks of treatment.
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Fig 2a. Genomic DNA from bone marrow mononuclear cells at complete histologic remission from follicular lymphoma (2002).
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Fig 6. mtDNA-encoded protein deformylation occurs in the mitochondria.
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Fig 2. Cumulative Incidence Functions for Utilization of Mammography Screenings Following Advanced Cancer Diagnosis by Cancer Site.
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Fig 1.(B) Summary of SDHB IHC scores in pediatric (n = 14) and adult (n = 12) WT GIST, KIT mutant GIST (n = 15), and NF-1–associated GIST (n = 5).
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Fig 5. CCDC40 mutations affect localization of CCDC39 in respiratory cells.
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Fig 1. PFS by adjuvant chemotherapy, yes/no (for stage II/III/IV and serous patients).
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Fig 1. Schematic representation of estimated disease extension at diagnosis of retinoblastoma in three different countries.
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Fig 3. Model for pathways involved in chromosomal translocations.
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Fig 1. Schematic representation of the mathematical model.
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TMLI isodose distribution shows the colorwash isodose distribution of a patient receiving 12 Gy TMLI.
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Fig 5a. Venn-diagram of genes differentially expressed in prospectively isolated CWR22 OT-tumour cells with low (expressing EpCAM, CD44 or α2-integrin), moderate (expressing TRA-1-60, CD151 or CD166) and high (triple-marker-positives) sphere/tumour-forming efficiencies (S/TFE).
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Fig 3B). Corresponding RCM and histological images of a superficial BCC. Corresponding histological section showing tumor nodules surrounded by mucin (black arrowheads).
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Fig 1. Bleomycin-induced pulmonary toxicity. Patient undergoing treatment for lymphoma presented with new-onset dyspnea and decrease in diffusing capacity 5 months after initiation of treatment.
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Fig 4. Molecular control of TGF-beta-induced Treg cell differentiation.
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This article reviews features of phase 2 trials in AML that may contribute to the high frequency of false-positive results, particularly lack of control groups, patient heterogeneity, selection bias, and choice of end points.
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A sequence consisting of a Lewis acid-catalyzed Diels−Alder reaction on a 2-halocyclohexenone, followed by reductive alkylation, provides a route to trans-fused octalinones bearing angular methyl groups with functionality corresponding to that which would have been possible from a trans-directed Diels−Alder reaction.
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Fig 8b. Evidence for transcriptional interference. The RNA signals (average of each replicate) for strains relevant to the transcriptional interference locus are displayed as line graphs.
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Fig 3. Antitumor Response in Each of the 32 Patients in the Extension Cohort.
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Fig 2. An esophagogastroduodenoscopy was performed, which revealed a PillCam SB (Given Imaging, Ltd) in the gastric body.
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Fig 2. Enhanced osteoclast differentiation in Id1-/- mice.
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Fig 2. Inhibition curves for deazaTh and deazaThDP.
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Fig 3.Immunoblotting for Parc and p53. a, control (untreated) cells showing abundant p53 and Parc; b, Parc knockdown after Parc siRNA interference, showing presence of a light Parc band confirming knockdown, but the p53 band still persists.
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Fig 1b. Chest radiograph of a patient after fracture of the mediport catheter from the subcutaneous reservoir. The catheter tubing has migrated to the right ventricle.
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Fig 1. Significant group differences were found for the FACT-Cx scale, in which the radical trachelectomy patients had a significantly more gradual linear improvement as well as a significantly less-prounounced arc in their trajectory compared to the radical hysterectomy patients.
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