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2009-10-01

Fig 1. Histological appearance of the recurrent tumor. A: Mature teratoma showing squamous epithelium lined cysts (Hematoxylin and Eosin stain at 40◊).

Fig 1. Histological appearance of the recurrent tumor. A: Mature teratoma showing squamous epithelium lined cysts (Hematoxylin and Eosin stain at 40◊).
  • Busse C, Nazeer T, Kanwar VS, Wolden S, LaQuaglia MP, Rosenblum M

  • Pediatr Blood Cancer. 2009 Oct;53(4):680-1.

2009-10-02

Fig 1. Posterior peripheral zone cancer (A) with TZ-LOOK morphology (B).

Fig 1. Posterior peripheral zone cancer (A) with TZ-LOOK morphology (B).
  • Haarer CF, Gopalan A, Tickoo SK, Scardino PT, Eastham JA, Reuter VE, Fine SW

  • J Urol. 2009 Oct;182(4):1337-41.

2009-10-05

Fig 3. Maximal reduction for indicator lesions (Response Evaluation Criteria in Solid Tumors classification) by EGFR and KRAS genotype.

Fig 3. Maximal reduction for indicator lesions (Response Evaluation Criteria in Solid Tumors classification) by EGFR and KRAS genotype.
  • Jackman DM, Miller VA, Cioffredi LA, Yeap BY, Jänne PA, Riely GJ, Ruiz MG, Giaccone G, Sequist LV, Johnson BE

  • Clin Cancer Res. 2009 Aug 15;15(16):5267-73.

2009-10-06

Fig 4. Effect of altered DC homeostasis on autoimmunity.

Fig 4. Effect of altered DC homeostasis on autoimmunity.
  • JDarrasse-Jèze G, Deroubaix S, Mouquet H, Victora GD, Eisenreich T, Yao KH, Masilamani RF, Dustin ML, Rudensky A, Liu K, Nussenzweig MC

  • J Exp Med. 2009 Aug 31;206(9):1853-62.

2009-10-07

Fig 1. The Overall Structure of Mms21 in Complex with the Arm Region of Smc5.

Fig 1. The Overall Structure of Mms21 in Complex with the Arm Region of Smc5.
  • Duan X, Sarangi P, Liu X, Rangi GK, Zhao X, Ye H

  • Mol Cell. 2009 Sep 11;35(5):657-68.

2009-10-08

Fig 6. CD14+CD16ñ and not CD14+CD16+ monocytes suppress germination of conidia.

Fig 6. CD14+CD16ñ and not CD14+CD16+ monocytes suppress germination of conidia.
  • Serbina NV, Cherny M, Shi C, Bleau SA, Collins NH, Young JW, Pamer EG

  • J Immunol. 2009 Aug 15;183(4):2678-87.

2009-10-09

Figure 1. Difference between groups in predicted outcome of treatment choice by maximum benefit. Light gray lines indicate 95% confidence intervals.

Figure 1. Difference between groups in predicted outcome of treatment choice by maximum benefit. Light gray lines indicate 95% confidence intervals.
  • Vickers AJ, Elkin EB, Peele PB, Dickler M, Siminoff LA.

  • Med Decis Making.2009 Jul-Aug;29(4):461-7.

2009-10-12

Fig 1. Siz/PIAS E3 Ligase Family Members and Structure of the Siz1 Catalytic Domain.

Fig 1. Siz/PIAS E3 Ligase Family Members and Structure of the Siz1 Catalytic Domain.
  • Yunus AA, Lima CD.

  • Mol Cell.2009 Sep 11;35(5):669-82.

2009-10-13

Fig 4 - ERG directly regulates CXCR4 and ADAMTS1.(c) CXCR4 siRNA knockdown demonstrates a significant reduction in cell migration in PC3 cells overexpressing ERG.

Fig 4 - ERG directly regulates CXCR4 and ADAMTS1.(c) CXCR4 siRNA knockdown demonstrates a significant reduction in cell migration in PC3 cells overexpressing ERG.
  • Carver BS, Tran J, Gopalan A, Chen Z, Shaikh S, Carracedo A, Alimonti A, Nardella C, Varmeh S, Scardino PT, Cordon-Cardo C, Gerald W, Pandolfi PP.

  • Nat Genet.2009 May;41(5):619-24.

2009-10-14

Fig 3. CTLA-4ñ/ñ T reg cell display diminished regulatory activity during in vitro suppressor assays.

Fig 3. CTLA-4ñ/ñ T reg cell display diminished regulatory activity during in vitro suppressor assays.
  • Peggs KS, Quezada SA, Chambers CA, Korman AJ, Allison JP

  • J Exp Med.2009 Aug 3;206(8):1717-25.

2009-10-15

Fig 1a. CT shows a 6.6-cm left adrenal mass.

Fig 1a. CT shows a 6.6-cm left adrenal mass.
  • Shah MH, Varker KA, Collamore M, Zwiebel JA, Coit D, Kelsen D, Chung KY

  • Am J Clin Oncol.2009 Apr;32(2):174-79.

2009-10-16

Fig. 1.  A, genomic profiles of multiple tumors from case 7. Both tumors displayed matching amplification and losses. B, closely matching allelic changes for 8 chromosome arms. aCGH array segmentation for tumor A (top) and B (bottom) are shown. Paired tumors exhibit similar genomic alterations, suggesting the diagnosis of metastases.

Fig. 1. A, genomic profiles of multiple tumors from case 7. Both tumors displayed matching amplification and losses. B, closely matching allelic changes for 8 chromosome arms. aCGH array segmentation for tumor A (top) and B (bottom) are shown. Paired tumors exhibit similar genomic alterations, suggesting the diagnosis of metastases.
  • Girard N, Ostrovnaya I, Lau C, Park B, Ladanyi M, Finley D, Deshpande C, Rusch V, Orlow I, Travis WD, Pao W, Begg CB

  • Clin Cancer Res.2009 Aug 15;15(16):5184-90.

2009-10-19

Fig 1. Proposed model for the regulatory roles played by Hsp90 in AD progression.

Fig 1. Proposed model for the regulatory roles played by Hsp90 in AD progression.
  • Luo W, Rodina A, Chiosis G

  • BMC Neurosci.2008 Dec 3;9 Suppl 2:S7.
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2009-10-20

Fig 5a. Immunofluorescence analysis of HIF-1a(?ODDD)/Fluc trafficking in the NIH3T3 reporter cell line.

Fig 5a. Immunofluorescence analysis of HIF-1a(?ODDD)/Fluc trafficking in the NIH3T3 reporter cell line.
  • Moroz E, Carlin S, Dyomina K, Burke S, Thaler HT, Blasberg R, Serganova I

  • PLoS One.2009;4(4):e5077.
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2009-10-21

Fig 7. Loss of p21 rescues functional BM-derived tumor angiogenesis in Id1-/- mice.

Fig 7. Loss of p21 rescues functional BM-derived tumor angiogenesis in Id1-/- mice.
  • Ciarrocchi A, Jankovic V, Shaked Y, Nolan DJ, Mittal V, Kerbel RS, Nimer SD, Benezra R

  • PLoS One. 2007 Dec 19;2(12):e1338.
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2009-10-22

Fig 1. Conceptual model of patient satisfaction and quality of life in breast surgery patients.

Fig 1. Conceptual model of patient satisfaction and quality of life in breast surgery patients.
  • Klassen AF, Pusic AL, Scott A, Klok J, Cano SJ

  • BMC Womens Health. 2009 May 1;9:11.
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2009-10-23

Fig 3. A Model of piRNA Biogenesis.

Fig 3. A Model of piRNA Biogenesis.
  • Betel D, Sheridan R, Marks DS, Sander C

  • PLoS Comput Biol.2007 Nov;3(11):e222.
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2009-10-26

Fig 1. A moderately dysplastic nevus. A, Side-transillumination. B, Cross-polarization. An automated boundary detection method was used to create the outline shown surrounding both images (black outlines)..

Fig 1. A moderately dysplastic nevus. A, Side-transillumination. B, Cross-polarization. An automated boundary detection method was used to create the outline shown surrounding both images (black outlines)..
  • Terushkin V, Dusza SW, Mullani NA, Duvic M, Zouridakis G, Weinstock M, Drugge R, Prieto VG, Dhawan A, Terry C, Talpur R, Marghoob AA

  • Arch Dermatol.2009 Sep;145(9):1060-2.

2009-10-27

Fig 2. Biopsy specimens stained with H&E (top) or analyzed by immunohistochemistry (IHC) using an anti-KIT antibody (bottom) show little, if any, difference before and after 1 wk of sunitinib treatment.

Fig 2. Biopsy specimens stained with H&E (top) or analyzed by immunohistochemistry (IHC) using an anti-KIT antibody (bottom) show little, if any, difference before and after 1 wk of sunitinib treatment.
  • Demetri GD, Heinrich MC, Fletcher JA, Fletcher CD, Van den Abbeele AD, Corless CL, Antonescu CR, George S, Morgan JA, Chen MH, Bello CL, Huang X, Cohen DP, Baum CM, Maki RG

  • Clin Cancer Res.2009 Sep 15;15(18):5902-9.

2009-10-28

Fig 5. Activity of MDV3100 in vitro (A) Localisation of YFP-tagged androgen receptor (AR) in LNCaP cells after treatment with indicated drugs.

Fig 5. Activity of MDV3100 in vitro (A) Localisation of YFP-tagged androgen receptor (AR) in LNCaP cells after treatment with indicated drugs.
  • Chen Y, Clegg NJ, Scher HI

  • Lancet Oncol.2009 Oct;10(10):981-91.

2009-10-29

Memorial Sloan-Kettering's Marc Ladanyi and others want to use tumor genetic profiling to match lung cancer patients with the best drug.

Memorial Sloan-Kettering's Marc Ladanyi and others want to use tumor genetic profiling to match lung cancer patients with the best drug.
  • Kaiser J

  • Science.2009 Oct 9;326(5950):218-20.

2009-11-02

Fig 6. Fluorescence in situ hybridisation analysis using a dual colour EWS breakapart rearrangement probe.

Fig 6. Fluorescence in situ hybridisation analysis using a dual colour EWS breakapart rearrangement probe.
  • Shingde MV, Buckland M, Busam KJ, McCarthy SW, Wilmott J, Thompson JF, Scolyer RA

  • J Clin Pathol.2009 Oct;62(10):915-9.

2009-11-03

Fig. 1. CT-X gene expression in breast cancer.

Fig. 1. CT-X gene expression in breast cancer.
  • Grigoriadis A, Caballero OL, Hoek KS, da Silva L, Chen YT, Shin SJ, Jungbluth AA, Miller LD, Clouston D, Cebon J, Old LJ, Lakhani SR, Simpson AJ, Neville AM

  • Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13493-8.

2009-11-04

FIGURE 4.  Biodistribution profile of 18F-FPA in nude mice with CWR22rv1 xenografts at 1, 2, 3, and 4 h after tail vein injection.

FIGURE 4. Biodistribution profile of 18F-FPA in nude mice with CWR22rv1 xenografts at 1, 2, 3, and 4 h after tail vein injection.
  • Pillarsetty N, Punzalan B, Larson SM

  • J Nucl Med. 2009 Oct;50(10):1709-14.

2009-11-05

Fig 1. Two GABAergic Inhibitory Circuits in the Spinal Cord.

Fig 1. Two GABAergic Inhibitory Circuits in the Spinal Cord.
  • Betley JN, Wright CV, Kawaguchi Y, Erdélyi F, Szabó G, Jessell TM, Kaltschmidt JA

  • Cell. 2009 Oct 2;139(1):161-74.

2009-11-06

Fig 1. Strategies to enhance immune function in the elderly improve the development, expansion, and function of T cells.

Fig 1. Strategies to enhance immune function in the elderly improve the development, expansion, and function of T cells.
  • Holland AM, van den Brink MR

  • Curr Opin Immunol.2009 Aug;21(4):454-9.

2009-11-09

Fig 1. Box plots showing the median VAS pain scores for the first 6 postoperative days between PCEA arm and PCA arm at rest. PCEA provided superior pain control compared to PCA on POD #1 at rest (low asteriskP = 0.01).

Fig 1. Box plots showing the median VAS pain scores for the first 6 postoperative days between PCEA arm and PCA arm at rest. PCEA provided superior pain control compared to PCA on POD #1 at rest (low asteriskP = 0.01).
  • Ferguson SE, Malhotra T, Seshan VE, Levine DA, Sonoda Y, Chi DS, Barakat RR, Abu-Rustum NR

  • EMBO Rep.2009 Aug;10(8):837-42.

2009-11-10

Fig 1. Responses to DNA double-strand breaks in S phase.

Fig 1. Responses to DNA double-strand breaks in S phase.
  • Costanzo V, Chaudhuri J, Fung JC, Moran JV

  • Gynecol Oncol.2009 Jul;114(1):111-6.

2009-11-11

Fig 2a. Surface representation and electrostatic potential of UBC9 proximal to the RanGAP SUMO consensus motif.

Fig 2a. Surface representation and electrostatic potential of UBC9 proximal to the RanGAP SUMO consensus motif.
  • Mohideen F, Capili AD, Bilimoria PM, Yamada T, Bonni A, Lima CD

  • Nat Struct Mol Biol.2009 Sep;16(9):945-52.

2009-11-12

Fig 2a. Progression-free survival by level of perioperative CA-125 response (all patients).

Fig 2a. Progression-free survival by level of perioperative CA-125 response (all patients).
  • Zivanovic O, Sima CS, Iasonos A, Bell-McGuinn KM, Sabbatini PJ, Leitao MM, Levine DA, Gardner GJ, Barakat RR, Chi DS

  • Gynecol Oncol.2009 Nov;115(2):209-14.

2009-11-13

Fig 2a. Triangulated F-18 FDG PET/CT image.

Fig 2a. Triangulated F-18 FDG PET/CT image.
  • Lu Y, Fox J, Dunphy M

  • Clin Nucl Med.2009 Oct;34(10):719-21.

2009-11-16

Fig 1b. p27Kip1 is mislocalized in TSC-inactive cerebella.

Fig 1b. p27Kip1 is mislocalized in TSC-inactive cerebella.
  • Bhatia B, Northcott PA, Hambardzumyan D, Govindarajan B, Brat DJ, Arbiser JL, Holland EC, Taylor MD, Kenney AM

  • Cancer Res.2009 Sep 15;69(18):7224-34.

2009-11-17

Fig 2b. High-grade postradiation breast AS, spindle cell type, harboring a D717V KDR mutation (H&E; magnification, x200).

Fig 2b. High-grade postradiation breast AS, spindle cell type, harboring a D717V KDR mutation (H&E; magnification, x200).
  • Antonescu CR, Yoshida A, Guo T, Chang NE, Zhang L, Agaram NP, Qin LX, Brennan MF, Singer S, Maki RG

  • Cancer Res. 2009 Sep 15;69(18):7175-9.

2009-11-18

Fig 1a. Preoperative magnetic resonance image (MRI) in the sagittal plane demonstrating tumor in the anterior and right lateral walls of the uterine cervix.

Fig 1a. Preoperative magnetic resonance image (MRI) in the sagittal plane demonstrating tumor in the anterior and right lateral walls of the uterine cervix.
  • Sidebotham EL, DeLair D, Comerci JT, Kayton ML, Abu-Rustum NR

  • Gynecol Oncol. 2009 Nov;115(2):302-5.

2009-11-20

Fig 1. CT image depicting a postoperative intra-abdominal collection (solid arrows) as defined by our criteria.

Fig 1. CT image depicting a postoperative intra-abdominal collection (solid arrows) as defined by our criteria.
  • Leitao MM Jr, Natenzon A, Abu-Rustum NR, Chi DS, Sonoda Y, Levine DA, Gardner GJ, Barakat RR

  • Gynecol Oncol. 2009 Nov;115(2):204-8.

2009-11-23

Fig 2. Expression analysis of the 5 CT candidates in tumor samples.

Fig 2. Expression analysis of the 5 CT candidates in tumor samples.
  • Bettoni F, Filho FC, Grosso DM, Galante PA, Parmigiani RB, Geraldo MV, Henrique-Silva F, Oba-Shinjo SM, Marie SK, Soares FA, Brentani HP, Simpson AJ, de Souza SJ, Camargo AA

  • Genomics. 2009 Sep;94(3):153-60.

2009-11-24

Fig 1. Major histocompatibility complex class I expression in neuroblastoma tumors.

Fig 1. Major histocompatibility complex class I expression in neuroblastoma tumors.
  • Reid GS, Shan X, Coughlin CM, Lassoued W, Pawel BR, Wexler LH, Thiele CJ, Tsokos M, Pinkus JL, Pinkus GS, Grupp SA, Vonderheide RH

  • Clin Cancer Res. 2009 Nov 1;15(21):6602-8.

2009-11-25

Fig 5b. 2D Lactate CSI from sagittal 5-mm thick slice using SS-SelMQC.

Fig 5b. 2D Lactate CSI from sagittal 5-mm thick slice using SS-SelMQC.
  • Thakur SB, Yaligar J, Koutcher JA

  • Magn Reson Med. Magn Reson Med.

2009-12-01

Fig 3. Instrumentation options for infertility evaluation.

Fig 3. Instrumentation options for infertility evaluation.
  • Noyes N, Abu-Rustum NR, Ramirez PT, Plante M

  • Gynecol Oncol. 2009 Jul;114(1):117-20.

2009-12-02

Fig 1. The differentiation hierarchy of the hematopoietic system.

Fig 1. The differentiation hierarchy of the hematopoietic system.
  • Haeno H, Levine RL, Gilliland DG, Michor F

  • Proc Natl Acad Sci USA. 2009 Sep 29;106(39):16616-21.
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2009-12-08

Fig 1: Driver mutations in chronic phase versus blast crisis.

Fig 1: Driver mutations in chronic phase versus blast crisis.
  • Sawyers CL

  • Nat Med. 2009 Oct;15(10):1158-61.

2009-12-09

Figure 7. Model for Differential miRNA Strand Selection by AGO1 and AGO2.

Figure 7. Model for Differential miRNA Strand Selection by AGO1 and AGO2.
  • Okamura K, Liu N, Lai EC

  • Mol Cell. 2009 Nov 13;36(3):431-44.

2009-12-10

Fig 1. A Decreasing Gradient of Id1 Levels in the Subventricular Neurogenic Lineages.

Fig 1. A Decreasing Gradient of Id1 Levels in the Subventricular Neurogenic Lineages.
  • Nam HS, Benezra R

  • Cell Stem Cell. 2009 Nov 6;5(5):515-26.

2009-12-14

Fig 4. Biodistribution profile of 18F-FPA in nude mice with CWR22rv1 xenografts at 1, 2, 3, and 4 h after tail vein injection.

Fig 4. Biodistribution profile of 18F-FPA in nude mice with CWR22rv1 xenografts at 1, 2, 3, and 4 h after tail vein injection.
  • Pillarsetty N, Punzalan B, Larson SM

  • J Nucl Med. 2009 Oct;50(10):1709-14.

2009-12-15

Fig 1a. Axis elongation in the Drosophila embryo.

Fig 1a. Axis elongation in the Drosophila embryo.
  • Zallen JA, Blankenship JT

  • Semin Cell Dev Biol. 2008 Jun;19(3):263-70.

2009-12-16

Fig 1. Exons of TET2 with locations of mutations and effect of mutations on overall survival in AML.

Fig 1. Exons of TET2 with locations of mutations and effect of mutations on overall survival in AML.
  • Abdel-Wahab O, Mullally A, Hedvat C, Garcia-Manero G, Patel J, Wadleigh M, Malinge S, Yao J, Kilpivaara O, Bhat R, Huberman K, Thomas S, Dolgalev I, Heguy A, Paietta E, Le Beau MM, Beran M, Tallman MS, Ebert BL, Kantarjian HM, Stone RM, Gilliland DG, Crispino JD, Levine RL

  • Blood. 2009 Jul 2;114(1):144-7.

2009-12-17

Fig 2. CT scan of the pelvis of an 18-year-old patient demonstrating a low rectal carcinoma (courtesy of M.P. La Quaglia: Memorial Sloan-Kettering Cancer Center).

Fig 2. CT scan of the pelvis of an 18-year-old patient demonstrating a low rectal carcinoma (courtesy of M.P. La Quaglia: Memorial Sloan-Kettering Cancer Center).
  • Zbuk K, Sidebotham EL, Bleyer A, La Quaglia MP

  • Semin Oncol. 2009 Oct;36(5):439-50.

2009-12-18

Fig 1. Host ASMase regulates graft-versus-host–associated morbidity, mortality, and target organ injury.

Fig 1. Host ASMase regulates graft-versus-host–associated morbidity, mortality, and target organ injury.
  • Rotolo JA, Stancevic B, Lu SX, Zhang J, Suh D, King CG, Kappel LW, Murphy GF, Liu C, Fuks Z, van den Brink MR, Kolesnick R

  • Blood. 2009 Oct 22;114(17):3693-706.

2009-12-21

Fig 1. Incidence of rhabdomyosarcoma (RMS) and non-RMS soft-tissue sarcomas in the pediatric age ranges from the SEER Program 1975-95, NCI.1.

Fig 1. Incidence of rhabdomyosarcoma (RMS) and non-RMS soft-tissue sarcomas in the pediatric age ranges from the SEER Program 1975-95, NCI.1.
  • Wolden SL, Alektiar KM

  • Semin Radiat Oncol. 2010 Jan;20(1):45-51.

2009-12-22

Fig 1. Strategies for selecting candidate genes from expression studies for functional analysis.

Fig 1. Strategies for selecting candidate genes from expression studies for functional analysis.
  • Vichas A, Zallen JA

  • J Biol. 2009 Sep 22;8(8):76.
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2009-12-23

Fig 3. Effect of anti-angiogenic treatment on mice carrying intracerebral GBM tumours.

Fig 3. Effect of anti-angiogenic treatment on mice carrying intracerebral GBM tumours.
  • Verhoeff JJ, Stalpers LJ, Claes A, Hovinga KE, Musters GD, Peter Vandertop W, Richel DJ, Leenders WP, van Furth WR

  • Eur J Cancer. 2009 Nov;45(17):3074-80.

2009-12-24

Fig 3. Protein expression of cancer/testis (CT) antigen in cancer.

Fig 3. Protein expression of cancer/testis (CT) antigen in cancer.
  • Caballero OL, Chen YT

  • Cancer Sci. 2009 Nov;100(11):2014-21.

2009-12-28

Fig 4. Neurogranin staining of adult brain sections shows that the inferior colliculus requires sustained Fgf8 signaling.

Fig 4. Neurogranin staining of adult brain sections shows that the inferior colliculus requires sustained Fgf8 signaling.
  • Sato T, Joyner AL

  • Development. 2009 Nov;136(21):3617-26.

2009-12-29

Fig 3. Combined inhibition of PI3K- and MAPK-signaling in cancer.

Fig 3. Combined inhibition of PI3K- and MAPK-signaling in cancer.
  • Sos ML, Fischer S, Ullrich R, Peifer M, Heuckmann JM, Koker M, Heynck S, Stuckrath I, Weiss J, Fischer F, Michel K, Goel A, Regales L, Politi KA, Perera S, Getlik M, Heukamp LC, Ansén S, Zander T, Beroukhim R, Kashkar H, Shokat KM, Sellers WR, Rauh D, Orr C, Hoeflich KP, Friedman L, Wong KK, Pao W, Thomas RK

  • Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18351-6.
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2009-12-30

Fig 3c. Dermatoscopy-confocal-histologic correlates of cobblestone nevus.

Fig 3c. Dermatoscopy-confocal-histologic correlates of cobblestone nevus.
  • Pellacani G, Scope A, Ferrari B, Pupelli G, Bassoli S, Longo C, Cesinaro AM, Argenziano G, Hofmann-Wellenhof R, Malvehy J, Marghoob AA, Puig S, Seidenari S, Soyer HP, Zalaudek I

  • J Am Acad Dermatol. 2009 Dec;61(6):1001-13.

2009-12-31

Fig 1b. Analysis of quantified western data in 20 GBM identifies three signaling axes associated with EGFR overexpression, PDGFB overexpression, and loss of NF1.

Fig 1b. Analysis of quantified western data in 20 GBM identifies three signaling axes associated with EGFR overexpression, PDGFB overexpression, and loss of NF1.
  • Brennan C, Momota H, Hambardzumyan D, Ozawa T, Tandon A, Pedraza A, Holland E

  • PLoS One. 2009 Nov 13;4(11):e7752.
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