Return to Today's science sparks archives

2009-01-02

Fig 3d. Electrostatic surface representation of the protein-RNA interface highlighting intermolecular contacts between G2-C3-U4 segment and MBNL1 ZnF4.

Fig 3d. Electrostatic surface representation of the protein-RNA interface highlighting intermolecular contacts between G2-C3-U4 segment and MBNL1 ZnF4.
  • Teplova M, Patel DJ

  • Nat Struct Mol Biol. 2008 Dec;15(12):1343-51.

2009-01-05

Fig 4a. Knockdown of SMAD6 induces cell arrest and increases apoptosis in H1299 cells.

Fig 4a. Knockdown of SMAD6 induces cell arrest and increases apoptosis in H1299 cells.
  • Jeon HS, Dracheva T, Yang SH, Meerzaman D, Fukuoka J, Shakoori A, Shilo K, Travis WD, Jen J

  • Cancer Res. 2008 Dec 1;68(23):9686-92.

2009-01-06

Fig 2b. Collagen gel treatment and decreased TGF-beta1 expression are associated with decreased scarring and fibrosis.

Fig 2b. Collagen gel treatment and decreased TGF-beta1 expression are associated with decreased scarring and fibrosis.
  • Clavin NW, Avraham T, Fernandez J, Daluvoy SV, Soares MA, Chaudhry A, Mehrara BJ

  • Am J Physiol Heart Circ Physiol. 2008 Nov;295(5):H2113-27.

2009-01-07

Fig 5a. Venn diagram illustrating the regulators involved in controlling hypoxically induced (oxygen-suppressed) genes in HAP1 and delta-hap1 cells, and heme-suppressed genes.

Fig 5a. Venn diagram illustrating the regulators involved in controlling hypoxically induced (oxygen-suppressed) genes in HAP1 and delta-hap1 cells, and heme-suppressed genes.
  • Kundaje A, Xin X, Lan C, Lianoglou S, Zhou M, Zhang L, Leslie C

  • PLoS Comput Biol. 2008 Nov;4(11):e1000224.

2009-01-08

Fig 1a. Representative FcRIIB-staining of a primary skin melanoma.

Fig 1a. Representative FcRIIB-staining of a primary skin melanoma.
  • Cassard L, Cohen-Solal JF, Fournier EM, Camilleri-BroÎt S, Spatz A, ChouaÔb S, Badoual C, Varin A, Fisson S, Duvillard P, Boix C, Loncar SM, Sastre-Garau X, Houghton AN, Avril MF, Gresser I, Fridman WH, SautËs-Fridman C

  • Int J Cancer. 2008 Dec 15;123(12):2832-9.

2009-01-09

Fig 2a. A pedunculated polypoid lesion emanating inferiorly from the posterior wall filled the entire nasopharynx and blocked the posterior choanae bilaterally. The lesion was excised.

Fig 2a. A pedunculated polypoid lesion emanating inferiorly from the posterior wall filled the entire nasopharynx and blocked the posterior choanae bilaterally. The lesion was excised.
  • Yoshida A, Borkar S, Singh B, Ghossein RA, Schˆder H

  • J Clin Oncol. 2008 Dec 10;26(35):5817-9.

2009-01-12

Fig 4. Left lower lobe, superior segment, again showing intraaalveolar macrophages (hematoxylin-eosin, original ◊ 40).

Fig 4. Left lower lobe, superior segment, again showing intraaalveolar macrophages (hematoxylin-eosin, original ◊ 40).
  • Chawla M, Boroumand N, Alexandrou C, Stover D

  • Chest. 2008 Dec;134(6):1320-4.

2009-01-13

Fig 12a. Intraductal papillary mucinous neoplasm (IPMN) with extension of the intraductal component into small duct branches in the fibrotic stroma, mimicking invasive carcinoma.

Fig 12a. Intraductal papillary mucinous neoplasm (IPMN) with extension of the intraductal component into small duct branches in the fibrotic stroma, mimicking invasive carcinoma.
  • Katabi N, Klimstra D

  • J Clin Pathol. 2008 Dec;61(12):1303-13.

2009-01-14

Fig 4d. γ

Fig 4d. γ
  • Liu Y, Elf SE, Miyata Y, Sashida G, Liu Y, Huang G, Di Giandomenico S, Lee JM, Deblasio A, Menendez S, Antipin J, Reva B, Koff A, Nimer SD

  • Cell Stem Cell. 2009 Jan 9;4(1):37-48.

2009-01-15

Fig 3b. A view of the most untwisted structure in G6G7*.

Fig 3b. A view of the most untwisted structure in G6G7*.
  • Cai Y, Patel DJ, Geacintov NE, Broyde S

  • J Mol Biol. 2009 Jan 9;385(1):30-44.

2009-01-16

Fig 1b. Colony assays documenting the effect of shRNAs targeting MYCN on the growth of IMR-32 and SH-EP cells. Cells were infected with the indicated retroviruses and grown in the presence of puromycin for 6 days.

Fig 1b. Colony assays documenting the effect of shRNAs targeting MYCN on the growth of IMR-32 and SH-EP cells. Cells were infected with the indicated retroviruses and grown in the presence of puromycin for 6 days.
  • Otto T, Horn S, Brockmann M, Eilers U, Sch¸ttrumpf L, Popov N, Kenney AM, Schulte JH, Beijersbergen R, Christiansen H, Berwanger B, Eilers M

  • Cancer Cell. 2009 Jan 6;15(1):67-78.

2009-01-19

Fig 6. The DDB2 Surface and Hairpin Are Important Structural Features of the Damage Recognition Process.

Fig 6. The DDB2 Surface and Hairpin Are Important Structural Features of the Damage Recognition Process.
  • Scrima A, KonÌckov· R, Czyzewski BK, Kawasaki Y, Jeffrey PD, Groisman R, Nakatani Y, Iwai S, Pavletich NP, Thom‰ NH

  • Cell. 2008 Dec 26;135(7):1213-23.

2009-01-21

Fig 1. Hsp90 inhibitors containing the 8-arylmethyl-9H-purin-6-amine core.

Fig 1. Hsp90 inhibitors containing the 8-arylmethyl-9H-purin-6-amine core.
  • Tao H, Kang Y, Taldone T, Chiosis G

  • Bioorg Med Chem Lett. 2009 Jan 15;19(2):415-7.

2009-01-22

Fig 1. Unsupervised cluster analysis of chondrosarcoma (red), chordoma (green) and soft tissue sarcoma (blue).

Fig 1. Unsupervised cluster analysis of chondrosarcoma (red), chordoma (green) and soft tissue sarcoma (blue).
  • Paparela P, Cronina AM, Savage C, Scardino PT, Eastham JA

  • Cancer Immunol Immunother. 2009 Mar;58(3):339-49.

2009-01-23

Fig 2. Kaplan-Meier probability of freedom from recurrence following salvage prostatectomy by biopsy Gleason score.

Fig 2. Kaplan-Meier probability of freedom from recurrence following salvage prostatectomy by biopsy Gleason score.
  • Paparela P, Cronina AM, Savage C, Scardino PT, Eastham JA

  • Eur Urol. 2009 Feb;55(2):404-411.

2009-01-26

Fig 1a. Venous phase magnetic resonance (MR) image of a recently ruptured liver cell adenoma encompassing nearly 50% of the right hemi liver and extending into the left hemi liver.

Fig 1a. Venous phase magnetic resonance (MR) image of a recently ruptured liver cell adenoma encompassing nearly 50% of the right hemi liver and extending into the left hemi liver.
  • Deneve JL, Pawlik TM, Cunningham S, Clary B, Reddy S, Scoggins CR, Martin RC, D'Angelica M, Staley CA, Choti MA, Jarnagin WR, Schulick RD, Kooby DA

  • Ann Surg Oncol. 2009 Jan 8.

2009-01-27

Fig 1c. In

Fig 1c. In
  • Agosti V, Karur V, Sathyanarayana P, Besmer P, Wojchowski DM

  • Exp Hematol. 2009 Feb;37(2):159-71.

2009-01-28

Fig 4c. Mdc1 recruitment is defective in WSTF-deficient cells. Immunofluorescent staining experiments were performed with anti-Mdc1 antibodies on control or WSTF RNAi cells, 8 h after 10 Gy of ionizing radiation treatment. DAPI, 4,6-diamidino-2-phenylindole.

Fig 4c. Mdc1 recruitment is defective in WSTF-deficient cells. Immunofluorescent staining experiments were performed with anti-Mdc1 antibodies on control or WSTF RNAi cells, 8 h after 10 Gy of ionizing radiation treatment. DAPI, 4,6-diamidino-2-phenylindole.
  • Xiao A, Li H, Shechter D, Ahn SH, Fabrizio LA, Erdjument-Bromage H, Ishibe-Murakami S, Wang B, Tempst P, Hofmann K, Patel DJ, Elledge SJ, Allis CD

  • Nature. 2009 Jan 1;457(7225):57-62.

2009-01-29

Fig 1b. Crystal structure of T. thermophilus Ago bound to 5'-phosphorylated 21-nucleotide guide DNA and 20-nucleotide target RNA.

Fig 1b. Crystal structure of T. thermophilus Ago bound to 5'-phosphorylated 21-nucleotide guide DNA and 20-nucleotide target RNA.
  • Wang Y, Juranek S, Li H, Sheng G, Tuschl T, Patel DJ

  • Nature. 2008 Dec 18;456(7224):921-6.

2009-01-30

Fig 2ab. Examples of baseline and follow-up contours for participant without previous head-and-neck rotation.

Fig 2ab. Examples of baseline and follow-up contours for participant without previous head-and-neck rotation.
  • Bekelman JE, Wolden S, Lee N

  • Int J Radiat Oncol Biol Phys. 2009 Feb 1;73(2):416-23.

2009-02-02

Fig 1. Cumulative Breast Cancer Incidence in Relatives of Probands.

Fig 1. Cumulative Breast Cancer Incidence in Relatives of Probands.
Highly cited
  • Begg CB, Haile RW, Borg A, Malone KE, Concannon P, Thomas DC, Langholz B, Bernstein L, Olsen JH, Lynch CF, Anton-Culver H, Capanu M, Liang X, Hummer AJ, Sima C, Bernstein JL

  • JAMA. 2008 Jan 9;299(2):194-201.

2009-02-03

Fig 1E. hESC-derived neural rosettes adopt polarized neuroepithelial structures of anterior CNS fate; day 16 rosettes colocalized with N-cad.

Fig 1E. hESC-derived neural rosettes adopt polarized neuroepithelial structures of anterior CNS fate; day 16 rosettes colocalized with N-cad.
Highly cited
  • Elkabetz Y, Panagiotakos G, Al Shamy G, Socci ND, Tabar V, Studer L

  • Genes Dev. 2008 May 1;22(9):1257.

2009-02-04

Fig 4D. Triple immunofluorescent merged images of human medulloblastoma samples showing existence of stem cell niches around blood vessels similar to mouse tumors.

Fig 4D. Triple immunofluorescent merged images of human medulloblastoma samples showing existence of stem cell niches around blood vessels similar to mouse tumors.
Highly cited
  • Hambardzumyan D, Becher OJ, Rosenblum MK, Pandolfi PP, Manova-Todorova K, Holland EC

  • Genes Dev. 2008 Feb 15;22(4):436-48.

2009-02-05

Fig 4E. Wild-type thorax.

Fig 4E. Wild-type thorax.
Highly cited
  • Tyler DM, Okamura K, Chung WJ, Hagen JW, Berezikov E, Hannon GJ, Lai EC

  • Genes Dev. 2008 Jan 1;22(1):26-36.

2009-02-06

Fig 3a. hpRNAs generate regulatory RNAs that can repress endogenous targets.

Fig 3a. hpRNAs generate regulatory RNAs that can repress endogenous targets.
Highly cited
  • Okamura K, Chung WJ, Ruby JG, Guo H, Bartel DP, Lai EC

  • Nature.2008 Jun 5;453(7196):803-6.

2009-02-09

Fig 4. Landmark analysis of overall survival according to the cytogenetic response at 12 months.

Fig 4. Landmark analysis of overall survival according to the cytogenetic response at 12 months.
Highly cited
  • Hochhaus A, Druker B, Sawyers C, Guilhot F, Schiffer CA, Cortes J, Niederwieser DW, Gambacorti-Passerini C, Stone RM, Goldman J, Fischer T, O'Brien SG, Reiffers JJ, Mone M, Krahnke T, Talpaz M, Kantarjian HM

  • Blood. 2008 Feb 1;111(3):1039-43.

2009-02-10

Fig 1.  PET Scans Obtained before T-Cell Infusion and 2 Months after Infusion.

Fig 1. PET Scans Obtained before T-Cell Infusion and 2 Months after Infusion.
Highly cited
  • Hunder NN, Wallen H, Cao J, Hendricks DW, Reilly JZ, Rodmyre R, Jungbluth A, Gnjatic S, Thompson JA, Yee C

  • N Engl J Med. 2008 Jun 19;358(25):2698-703.

2009-02-11

Fig 1a. Progression-free survival.

Fig 1a. Progression-free survival.
Highly cited
  • Miller VA, Riely GJ, Zakowski MF, Li AR, Patel JD, Heelan RT, Kris MG, Sandler AB, Carbone DP, Tsao A, Herbst RS, Heller G, Ladanyi M, Pao W, Johnson DH

  • J Clin Oncol. 2008 Mar 20;26(9):1472-8.

2009-02-12

Figure 2a. IL-10 controls T cell tolerance at the interface between the innate and the adaptive immune systems.

Figure 2a. IL-10 controls T cell tolerance at the interface between the innate and the adaptive immune systems.
Highly cited
  • Li MO, Flavell RA

  • Immunity. 2008 Apr;28(4):468-76.

2009-02-13

Fig 2. Mean monthly untransfused hemoglobin levels in TI responders and nonresponders (N = 214).

Fig 2. Mean monthly untransfused hemoglobin levels in TI responders and nonresponders (N = 214).
Highly cited
  • Raza A, Reeves JA, Feldman EJ, Dewald GW, Bennett JM, Deeg HJ, Dreisbach L, Schiffer CA, Stone RM, Greenberg PL, Curtin PT, Klimek VM, Shammo JM, Thomas D, Knight RD, Schmidt M, Wride K, Zeldis JB, List AF

  • Blood. 2008 Jan 1;111(1):86-93.

2009-02-16

Fig 1b. The steric role of PSA at the cell surface. A schematic representation of molecular interactions during membraneñmembrane contact.

Fig 1b. The steric role of PSA at the cell surface. A schematic representation of molecular interactions during membraneñmembrane contact.
Highly cited
  • Rutishauser U

  • Nat Rev Neurosci. 2008 Jan;9(1):26-35.

2009-02-17

Fig 4c. CD133 is expressed in differentiated epithelium of normal human colon.

Fig 4c. CD133 is expressed in differentiated epithelium of normal human colon.
Highly cited
  • Shmelkov SV, Butler JM, Hooper AT, Hormigo A, Kushner J, Milde T, St Clair R, Baljevic M, White I, Jin DK, Chadburn A, Murphy AJ, Valenzuela DM, Gale NW, Thurston G, Yancopoulos GD, D'Angelica M, Kemeny N, Lyden D, Rafii S

  • J Clin Invest. 2008 Jun;118(6):2111-20.

2009-02-18

Fig 1. Prostate cancer clinical-states model, a framework for patient management and drug development.

Fig 1. Prostate cancer clinical-states model, a framework for patient management and drug development.
Highly cited
  • Scher HI, Halabi S, Tannock I, Morris M, Sternberg CN, Carducci MA, Eisenberger MA, Higano C, Bubley GJ, Dreicer R, Petrylak D, Kantoff P, Basch E, Kelly WK, Figg WD, Small EJ, Beer TM, Wilding G, Martin A, Hussain M; Prostate Cancer Clinical Trials Working Group

  • J Clin Oncol. 2008 Mar 1;26(7):1148-59.

2009-02-19

Fig 1F.  PGCs, HSCs, and blood progenitors in the zebrafish at not, vert, similar 24ñ28 hours postfertilization.

Fig 1F. PGCs, HSCs, and blood progenitors in the zebrafish at not, vert, similar 24ñ28 hours postfertilization.
Highly cited
  • Laird DJ, von Andrian UH, Wagers AJ

  • Cell. 2008 Feb 22;132(4):612-30.

2009-02-20

Fig 1b. Ribbon diagram of the structure of the Aquifex aeolicus Piwi protein, showing its bilobed architecture.

Fig 1b. Ribbon diagram of the structure of the Aquifex aeolicus Piwi protein, showing its bilobed architecture.
Highly cited
  • Farazi TA, Juranek SA, Tuschl T

  • Development. 2008 Apr;135(7):1201-14.

2009-02-23

Fig 2. Progression-free survival (intent to treat population).

Fig 2. Progression-free survival (intent to treat population).
Highly cited
  • Saltz LB, Clarke S, Díaz-Rubio E, Scheithauer W, Figer A, Wong R, Koski S, Lichinitser M, Yang TS, Rivera F, Couture F, SirzÈn F, Cassidy J

  • J Clin Oncol. 2008 Apr 20;26(12):2013-9.

2009-02-24

Blood celebrates the 50th anniversary of the American Society of Hematology. The Blood cover has evolved over the past 50 years, as shown. Illustration by A. Y. Chen.

Blood celebrates the 50th anniversary of the American Society of Hematology. The Blood cover has evolved over the past 50 years, as shown. Illustration by A. Y. Chen.
Highly cited
  • Rizzo JD, Somerfield MR, Hagerty KL, Seidenfeld J, Bohlius J, Bennett CL, Cella DF, Djulbegovic B, Goode MJ, Jakubowski AA, Rarick MU, Regan DH, Lichtin AE

  • Blood. 2008 Jan 1;111(1):25-41.

2009-02-25

Fig 1D. Chromosome analysis of CAPAN1 cells exposed to MMC for 24 h. Arrows indicate chromatid breaks, triradials and other chromosome aberrations.

Fig 1D. Chromosome analysis of CAPAN1 cells exposed to MMC for 24 h. Arrows indicate chromatid breaks, triradials and other chromosome aberrations.
Highly cited
  • Edwards SL, Brough R, Lord CJ, Natrajan R, Vatcheva R, Levine DA, Boyd J, Reis-Filho JS, Ashworth A

  • Nature. 2008 Feb 28;451(7182):1111-5.

2009-02-26

Fig 5b. FISH analysis of the TMPRSS2 and ERG loci in 2+Edel cancers.

Fig 5b. FISH analysis of the TMPRSS2 and ERG loci in 2+Edel cancers.
Highly cited
  • Attard G, Clark J, Ambroisine L, Fisher G, Kovacs G, Flohr P, Berney D, Foster CS, Fletcher A, Gerald WL, Moller H, Reuter V, De Bono JS, Scardino P, Cuzick J, Cooper CS; Transatlantic Prostate Group

  • Oncogene. 2008 Jan 10;27(3):253-63.

2009-02-27

As the official journal of the AGA Institute, Gastroenterology delivers up-to-date and authoritative coverage of both basic and clinical gastroenterology.

As the official journal of the AGA Institute, Gastroenterology delivers up-to-date and authoritative coverage of both basic and clinical gastroenterology.
Highly cited
  • Levin B, Lieberman DA, McFarland B, Andrews KS, Brooks D, Bond J, Dash C, Giardiello FM, Glick S, Johnson D, Johnson CD, Levin TR, Pickhardt PJ, Rex DK, Smith RA, Thorson A, Winawer SJ; American Cancer Society Colorectal Cancer Advisory Group; US Multi-Society Task Force; American College of Radiology Colon Cancer Committeep

  • Gastroenterology. 2008 May;134(5):1570-95.

2009-03-02

CA: A Cancer Journal for Clinicians is a peer-reviewed journal of the American Cancer Society providing cancer care professionals with up-to-date information on all aspects of cancer diagnosis, treatment, and prevention.

CA: A Cancer Journal for Clinicians is a peer-reviewed journal of the American Cancer Society providing cancer care professionals with up-to-date information on all aspects of cancer diagnosis, treatment, and prevention.
  • Levin B, Lieberman DA, McFarland B, Andrews KS, Brooks D, Bond J, Dash C, Giardiello FM, Glick S, Johnson D, Johnson CD, Levin TR, Pickhardt PJ, Rex DK, Smith RA, Thorson A, Winawer SJ, American Cancer Society Colorectal Cancer Advisory Group, US Multi-Society Task Force, American College of Radiology Colon Cancer Committee

  • CA Cancer J Clin. 2008 May-Jun;58(3):130-60.

2009-03-03

Fig 4. Graphic illustrating the roles of 8 genes implicated in the present study in lithium-sensitive signaling pathways.

Fig 4. Graphic illustrating the roles of 8 genes implicated in the present study in lithium-sensitive signaling pathways.
  • Baum AE, Akula N, Cabanero M, Cardona I, Corona W, Klemens B, Schulze TG, Cichon S, Rietschel M, Nˆthen MM, Georgi A, Schumacher J, Schwarz M, Abou Jamra R, Hˆfels S, Propping P, Satagopan J, Detera-Wadleigh SD, Hardy J, McMahon FJ

  • Mol Psychiatry. 2008 Feb;13(2):197-207.

2009-03-04

Fig 10. LysoTracker Red stains lysosomes and can be used to monitor autophagy in Drosophila melanogaster.

Fig 10. LysoTracker Red stains lysosomes and can be used to monitor autophagy in Drosophila melanogaster.
  • Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, Blum JS, Bredesen DE, Brodsky JL, Brumell JH, Brunk UT, Bursch W, Camougrand N, Cebollero E, Cecconi F, Chen Y, Chin LS, Choi A, Chu CT, Chung J, Clarke PG, Clark RS, Clarke SG, ClavÈ C, Cleveland JL, Codogno P, Colombo MI, Coto-Montes A, Cregg JM, Cuervo AM, Debnath J, Demarchi F, Dennis PB, Dennis PA, Deretic V, Devenish RJ, Di Sano F, Dice JF, Difiglia M, Dinesh-Kumar S, Distelhorst CW, Djavaheri-Mergny M, Dorsey FC, Dröge W, Dron M, Dunn WA Jr, Duszenko M, Eissa NT, Elazar Z, Esclatine A, Eskelinen EL, Fésüs L, Finley KD, Fuentes JM, Fueyo J, Fujisaki K, Galliot B, Gao FB, Gewirtz DA, Gibson SB, Gohla A, Goldberg AL, Gonzalez R, González-Estévez C, Gorski S, Gottlieb RA, Häussinger D, He YW, Heidenreich K, Hill JA, Høyer-Hansen M, Hu X, Huang WP, Iwasaki A, Jäättelä M, Jackson WT, Jiang X, Jin S, Johansen T, Jung JU, Kadowaki M, Kang C, Kelekar A, Kessel DH, Kiel JA, Kim HP, Kimchi A, Kinsella TJ, Kiselyov K, Kitamoto K, Knecht E, Komatsu M, Kominami E, Kondo S, Kovács AL, Kroemer G, Kuan CY, Kumar R, Kundu M, Landry J, Laporte M, Le W, Lei HY, Lenardo MJ, Levine B, Lieberman A, Lim KL, Lin FC, Liou W, Liu LF, Lopez-Berestein G, López-Otín C, Lu B, Macleod KF, Malorni W, Martinet W, Matsuoka K, Mautner J, Meijer AJ, Meléndez A, Michels P, Miotto G, Mistiaen WP, Mizushima N, Mograbi B, Monastyrska I, Moore MN, Moreira PI, Moriyasu Y, Motyl T, Münz C, Murphy LO, Naqvi NI, Neufeld TP, Nishino I, Nixon RA, Noda T, Nürnberg B, Ogawa M, Oleinick NL, Olsen LJ, Ozpolat B, Paglin S, Palmer GE, Papassideri I, Parkes M, Perlmutter DH, Perry G, Piacentini M, Pinkas-Kramarski R, Prescott M, Proikas-Cezanne T, Raben N, Rami A, Reggiori F, Rohrer B, Rubinsztein DC, Ryan KM, Sadoshima J, Sakagami H, Sakai Y, Sandri M, Sasakawa C, Sass M, Schneider C, Seglen PO, Seleverstov O, Settleman J, Shacka JJ, Shapiro IM, Sibirny A, Silva-Zacarin EC, Simon HU, Simone C, Simonsen A, Smith MA, Spanel-Borowski K, Srinivas V, Steeves M, Stenmark H, Stromhaug PE, Subauste CS, Sugimoto S, Sulzer D, Suzuki T, Swanson MS, Tabas I, Takeshita F, Talbot NJ, Tallóczy Z, Tanaka K, Tanaka K, Tanida I, Taylor GS, Taylor JP, Terman A, Tettamanti G, Thompson CB, Thumm M, Tolkovsky AM, Tooze SA, Truant R, Tumanovska LV, Uchiyama Y, Ueno T, Uzcátegui NL, van der Klei I, Vaquero EC, Vellai T, Vogel MW, Wang HG, Webster P, Wiley JW, Xi Z, Xiao G, Yahalom J, Yang JM, Yap G, Yin XM, Yoshimori T, Yu L, Yue Z, Yuzaki M, Zabirnyk O, Zheng X, Zhu X, Deter RL

  • Autophagy. 2008 Feb 16;4(2):151-75.

2009-03-05

Fig 2c. Parental MDA-MB-231 cells and lung metastatic LM2 cells expressing miR-126, miR-335 or miR-206 were seeded onto glass slides. Cells were stained with the actin marker phalloidin and confocal images were obtained.

Fig 2c. Parental MDA-MB-231 cells and lung metastatic LM2 cells expressing miR-126, miR-335 or miR-206 were seeded onto glass slides. Cells were stained with the actin marker phalloidin and confocal images were obtained.
  • Tavazoie SF, Alarcón C, Oskarsson T, Padua D, Wang Q, Bos PD, Gerald WL, Massagué J

  • Nature. 2008 Jan 10;451(7175):147-52.

2009-03-06

Fig 1. Autocrine IL-6 Mediates gp130/JAK/STAT3 Signaling and Promotes Tumorigenesis.

Fig 1. Autocrine IL-6 Mediates gp130/JAK/STAT3 Signaling and Promotes Tumorigenesis.
  • Bromberg J, Wang TC

  • Cancer Cell. 2009 Feb 3;15(2):79-80.

2009-03-09

Fig 1. Both hindbrain and midbrain floor plate are dependent on Shh for floor plate induction.

Fig 1. Both hindbrain and midbrain floor plate are dependent on Shh for floor plate induction.
  • Fasano CA, Studer L

  • Nat Neurosci. 2009 Feb;12(2):107-8.

2009-03-10

Fig 1. Canonical miRNA and mirtron pathways in Drosophila.

Fig 1. Canonical miRNA and mirtron pathways in Drosophila.
  • Martin R, Smibert P, Yalcin A, Tyler DM, Schäfer U, Tuschl T, Lai EC

  • Mol Cell Biol. 2009 Feb;29(3):861-70.

2009-03-11

Fig 1. Coronal slice representative of isodose distribution of typical treatment plan delivered for thyroid cancer for 69-year-old man who had presented with recurrent medullary thyroid cancer.

Fig 1. Coronal slice representative of isodose distribution of typical treatment plan delivered for thyroid cancer for 69-year-old man who had presented with recurrent medullary thyroid cancer.
  • Terezakis SA, Lee KS, Ghossein RA, Rivera M, Tuttle RM, Wolden SL, Zelefsky MJ, Wong RJ, Patel SG, Pfister DG, Shaha AR, Lee NY

  • Int J Radiat Oncol Biol Phys. 2009 Mar 1;73(3):795-801.

2009-03-12

Fig 1c. Prostate specific overexpression of ERG does not induce high grade prostatic intra-epithelial neoplasia.

Fig 1c. Prostate specific overexpression of ERG does not induce high grade prostatic intra-epithelial neoplasia.
  • Carver BS, Tran J, Chen Z, Carracedo-Perez A, Alimonti A, Nardella C, Gopalan A, Scardino PT, Cordon-Cardo C, Gerald W, Pandolfi PP

  • Nature. 2009 Feb 12;457(7231):E1; discussion E2-3.

2009-03-13

Fig 1. Phosphorylation (activation) of ERM proteins is dynamically regulated during metastatic progression.

Fig 1. Phosphorylation (activation) of ERM proteins is dynamically regulated during metastatic progression.
  • Ren L, Hong SH, Cassavaugh J, Osborne T, Chou AJ, Kim SY, Gorlick R, Hewitt SM, Khanna C

  • Oncogene. 2009 Feb 12;28(6):792-802.

2009-03-17

Fig 2. X-ray crystallographic structure of 12: CCDC 710680.

Fig 2. X-ray crystallographic structure of 12: CCDC 710680.
  • Yang G, Yin YI, Chun J, Shelton CC, Ouerfelli O, Li YM

  • Bioorg Med Chem Lett. 2009 Feb 1;19(3):922-5.

2009-03-18

Fig 6. Actively metabolizing tumor with pre- and posttreatment uptake of 18F-FDHT, an androgen ligand radiotracer, in multiple lumbar vertebrae before (left) and after (right) treatment with Medivation, a high-affinity androgen receptor being studied under approved protocol at MSKCC.

Fig 6. Actively metabolizing tumor with pre- and posttreatment uptake of 18F-FDHT, an androgen ligand radiotracer, in multiple lumbar vertebrae before (left) and after (right) treatment with Medivation, a high-affinity androgen receptor being studied under approved protocol at MSKCC.
  • Zhao B, Schwartz LH, Larson SM

  • J Nucl Med. 2009 Feb;50(2):239-49.

2009-03-20

Fig 1. Radiographic response at tumor core but overall size of lesion measured as stable disease (SD) by RECIST criteria.

Fig 1. Radiographic response at tumor core but overall size of lesion measured as stable disease (SD) by RECIST criteria.
  • Kreisl TN, Lassman AB, Mischel PS, Rosen N, Scher HI, Teruya-Feldstein J, Shaffer D, Lis E, Abrey LE

  • J Neurooncol.2009 Feb 1;19(3):922-5.

2009-03-23

Fig 5B. Immunofluorescence by confocal microscopy on A and G0 cells using p27 (panels 1) or phosphoY89p27 (panels 2) antibodies.

Fig 5B. Immunofluorescence by confocal microscopy on A and G0 cells using p27 (panels 1) or phosphoY89p27 (panels 2) antibodies.
  • Ray A, James MK, Larochelle S, Fisher RP, Blain SW

  • Mol Cell Biol.2009 Feb;29(4):986-99.

2009-03-24

Fig 1a.  Isodose curves and doseñvolume histogram of T2N1M0 oral tongue cancer with negative margins treated with dose-painting technique.

Fig 1a. Isodose curves and doseñvolume histogram of T2N1M0 oral tongue cancer with negative margins treated with dose-painting technique.
  • Gomez DR, Zhung JE, Gomez J, Chan K, Wu AJ, Wolden SL, Pfister DG, Shaha A, Shah JP, Kraus DH, Wong RJ, Lee NY

  • Int J Radiat Oncol Biol Phys. 2009 Mar 15;73(4):1096-103.

2009-03-25

Fig 3. Effect of rMETase with or without vincristine on cell cycle arrest of SK-N-BE(2)C.

Fig 3. Effect of rMETase with or without vincristine on cell cycle arrest of SK-N-BE(2)C.
  • Hu J, Cheung NK

  • Int J Cancer. 2009 Apr 1;124(7):1700-6.

2009-03-26

Fig 1. Hyperplasia of ICC in the stomachs of Kit<sup>V558&#x394;</sup>/+ mice.

Fig 1. Hyperplasia of ICC in the stomachs of Kit<sup>V558&#x394;</sup>/+ mice.
  • Kwon JG, Hwang SJ, Hennig GW, Bayguinov Y, McCann C, Chen H, Rossi F, Besmer P, Sanders KM, Ward SM

  • Gastroenterology. 2009 Feb;136(2):630-9.

2009-03-27

Fig 7. Interaction between MreB and Topo IV May Help Coordinate Late Cell-Cycle Events.

Fig 7. Interaction between MreB and Topo IV May Help Coordinate Late Cell-Cycle Events.
  • Madabhushi R, Marians KJ

  • Mol Cell. 2009 Jan 30;33(2):171-80.

2009-03-30

Fig 7c. Model of positive regulation of DNA-damage-induced oligomerization of Rad9 dimers via BRCT-SCD interaction.

Fig 7c. Model of positive regulation of DNA-damage-induced oligomerization of Rad9 dimers via BRCT-SCD interaction.
  • Usui T, Foster SS, Petrini JH

  • Mol Cell. 2009 Jan 30;33(2):147-59.

2009-03-31

Fig 1a. CT antigen expression in hepatobiliary carcinomas.

Fig 1a. CT antigen expression in hepatobiliary carcinomas.
  • Riener MO, Wild PJ, Soll C, Knuth A, Jin B, Jungbluth A, Hellerbrand C, Clavien PA, Moch H, Jochum W

  • Int J Cancer. 2009 Jan 15;124(2):352-7.

2009-04-01

Fig 2b. Total neurosphere cultures prepared from PDGF-induced tumors stain positive for various stem cell markers such as nestin, Oct4, Sox2, Musashi, ABCG2, and GFAP.

Fig 2b. Total neurosphere cultures prepared from PDGF-induced tumors stain positive for various stem cell markers such as nestin, Oct4, Sox2, Musashi, ABCG2, and GFAP.
  • Bleau AM, Hambardzumyan D, Ozawa T, Fomchenko EI, Huse JT, Brennan CW, Holland EC

  • Cell Stem Cell. 2009 Mar 6;4(3):226-35.