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Fig 2c. Colocalization of Alexa Fluor 488ñlabeled TA99 (green) with macrophage marker f/480 APC (pink; x40).
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Fig 2b. Overall structure of the aptamerñthrombin complex. The A-Arg zipper, shown as a stereo representation. Two protein arginines (yellow) intercalate with adenine RNA bases (green).
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Fig 1d. 52-year-old man with bladder carcinoma presenting with left flank pain from pyelonephritis 2 years after radical cystectomy with urinary diversion to ileal conduit.
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Fig 1d. Fluorescent microscopy of U87/{Delta}hTK2 GFP cells using GFP filter set.
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Fig 1c. Infiltrative tumor growth pattern in Merkel cell carcinoma shown at low magnification.
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Fig 1. ìTZ-LOOKîóvariably shaped glands displaying pale cytoplasm and basally oriented nuclei.
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Fig. 5a-d Generation of functional E4ORF1+ ECs capable of tubulogenesis, sprouting, and support of tumor cell growth.
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Fig 2. Reconstructed coronal view of brachial plexus (BP) generated from contours shown in Fig 1.
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Fig 3. PCNA binding by PIP domains is essential for accumulation of hPol eta in replication foci.
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Fig 2b. PSMA is expressed in pleural granulation tissue H&E.
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Fig 3b. Assessment of BCR-ABL kinase activity in K562 cells through analysis of phospho-CRKL and phospho-STAT5 following treatment for 20 min with varying concentrations of dasatinib.
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Fig 2b. Whole mount section with cancer in the right peripheral zone showing a positive surgical margin (arrow).
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Fig 1c. Crystal structure of T. thermophilus argonaute bound to a 5'-phosphorylated 21-base DNA guide strand.
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Fig 3b(1). Graphical representation of reaction of murine tumors with different agents.
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Fig 6. Helical models of peptide substrate and cleavage sites. The helical wheel was modeled with Lasergene 6. The cleavage sites in the WT, C146A, and M145A substrates are denoted with arrows.
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Fig 2a. CD-GFP cells were transplanted into epithelium-free mammary fat pads and imaged by fluorescence microscopy 41 weeks after transplantation.
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Fig 2a. Structure and interactions in the junctional region of the lysine riboswitch.
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Fig 1. Sequential Activation of Innate Immune Responses during Bacterial Infection.
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Fig 5a. Insights to CTD Recognition.
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Fig 6b. A 62-year-old man who has a 4.6-cm solid vascular clear cell carcinoma in the left upper pole. US demonstrates flow in the mass on color Doppler.
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Fig 1. Phospho-PDGFR expression in peripheral blood leukocytes by immunofluorescent antibody staining.
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Fig 1. Mouse embryonic fibroblasts (MEFs).
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Fig 1. Generation of trisomic embryos and MEF cell lines.
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Fig 1. GATE simulation model of the GE Advance/Discovery LS PET scanner.
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Fig 1. Histology and autoradiography of Salmonella VNP20009-TK localization in s.c. C38 tumors.
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Fig 1. Cortical responses obtained from voxel-wise comparisons of the high and low pitch tasks based on averaged group data.
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Fig 3d. p53 and Pten coordinately regulate Myc protein level as well as NSC self-renewal and differentiation.
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Fig 3. Delta-T2 map of telomerase protein (hTERT).
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Fig 1c. PCR analysis of genomic DNA or viral RNA derived from either tranduced T cells or packaging cells.
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Fig 3a. Vitamin C attenuates the cytotoxicity of antineoplastic agents in vivo. ICR SCID mice were xenografted with RL cells in the right flank.
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Fig 4a. Validation analyses: protein expression of c-met is associated with tumor staging and overall survival.
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Fig 3b. Effect of MTH on tumor hypoxia.
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Fig 6a. The effect of breathing 10% O2 on tumor hypoxia.
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Fig 4C. Configurations of microRNA (miRNA)ñtarget networks. Although most animal miRNAs are likely to influence a battery of targets in a given cell, the phenotype caused by loss of a miRNA might demonstrably be due to one or a few targets.
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Fig. 1 Examples of longitudinally incised aortas obtained from ChDñapoEñ/ñ, ChDñwild-type, and normal dietñwild-type mice and stained with Oil Red O (at age of 25 wk). Regions stained red with Oil Red O represent atherosclerotic lesions.
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Fig 4. WLI initially appeared normal, but a cluster of papillary tumours is clearly visible on NBI cystoscopy.
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Fig 1a. Photomicrograph in 75-year-old man who underwent RF ablation for treatment of 3.3-cm HCC in liver segment 4. (a) H-E stain shows cells with preserved morphologic characteristics, suggesting viable tumor.
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Fig 3. TUNEL-positive cells were scattered at mid layer of myocardial area at risk in nT group.
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Fig 3H. HAUSP regulates PTEN localization. IHC of prostate TMA for PTEN and HAUSP (left) and quantification (right, n = 81). Arrow, nuclear PTEN (HAUSPlow); arrowhead, cytoplasmic PTEN (HAUSPhigh).
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Fig 6a. Structural basis for cargo discrimination by human Sec24 isoforms.
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Fig 5. C7 Th1 cells confer protection to M. tuberculosis only after day 7 following infection. (AñC) 107 C7 Th1 cells (CD90.1) were transferred into B6 recipient mice (CD90.2), and 1 d later splenocytes or lung cells were harvested and stained for CD4 and CD90.1 expression. (A) Gate marks donor-derived cells among total cells in the indicated organs.
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Fig 3a. Mitochondrial ceramide mediates CED-4 displacement.
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Figure 3. Metastatic acinar cell carcinoma to the ovary showing a cribriform pattern of growth with prominent central necrosis (case 2).
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Fig 2B. Fluorescent Proteins as Cell Tracers in Visceral Endoderm-Derived Cells that Are Downregulating Marker Genes. 3D reconstruction of z stack from an Afp::GFPTg/+; Ttr::RFPTg/+ transgenic projected laterally (left) and posteriorly (right). Coexpressing cells are yellow.
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Fig 5a. Misexpression of Tbr2 Promotes SVZ Ectopic Proliferation and Cell-Cycle Maintenance.
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Fig 2. The secretion of lytic granules is compared with what is known about synaptic and multidirectional cytokines from activated T cells.
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Fig 3E.
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Fig 1. Dose distribution of axial slice through celiac axis.
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Fig 2. Mechanisms of immunoglobulin class-switch recombination.
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Fig 5. Quantitative real-time polymerase chain reaction analysis of lipogenic differentiation (lipoprotein lipase and CCAAT enhancer-binding protein-alpha).
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Fig 2. Anteroposterior (left) and lateral (right) radiographs obtained in a 52-year-old man with chordoma who underwent C5ñ6 corpectomy with C5ñ7 posterolateral resection and a 2-level facetectomy.
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Fig 2c. T-cell cannibalism by metastatic melanoma.
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Fig 1. An ovarian tumor cell staining positive for NY-ESO-1 by immunohistochemistry.
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Fig 7a. Hhat-mediated Shh palmitoylation occurs within the secretory pathway. COS-1 cells transfected with Hhat-HA alone or with full-length Shh were fixed and processed for indirect immunofluorescence. Hhat-HA colocalization with protein-disulfide isomerase (PDI)(A), mannosidase II.
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Fig 2. Regulation of PTEN (phosphatase and tensin homolog deleted on chromosome 10) function and stability by its C-terminal fragment.
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Fig 2. Binding site surface of the crystal structure of the C1b domain of PKCδ1 (A) compared to homology models of RasGRP1 (B). Residues are colored according to hydrophobicity35 from highly hydrophobic residues in red to hydrophilic residues in blue.
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Fig 1. Possible reaction pathways for the MABR-mediated rearrangement.
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Fig 1. Chest CT scans showing cystic changes of LAM and pleurally based masses with high attennation
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Fig 8. Schematic representation of the pathway described in the study.
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