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Fig 2a. Results of 2880 Compound Library Screen. Scale bar corresponds to 80 micrometer.
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Fig 2e. Pathology in nonspecific interstitial pneumonia. Interstitial fibrosis with airspace enlargement.
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Fig 1a. merm Mutant Phenotype and Characterization of the merm Allele.
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Fig 6. Characteristic immunophenotype of mucinous IM-LMP neoplasms arising in association with mature teratomas.
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Fig 9b. This figure shows the average dose maps for patients without toxicity.
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Fig 2e. Active Notch Signaling Initiates Lineage Commitment of hESCs. H9 cells stably transduced with parental or ICNER lentivector were cultured on Matrigel in the absence or presence of 4HT (200 nM) for 6 days. In an independent experiment, 8 day treated cells were stained for Oct4 antibody.
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Fig 2a. Effector functions of inflammatory monocytes. While most CCR2+ monocytes are not infected in vivo, monocytes in the peripheal circulation may become infected with L. monocytogenes and transport bacteria to the CNS.
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Fig 3b. Dual-color fluorescence in situ hybridization (FISH) on touch preparation sections with a centromeric probe for chromosome 7 (green) in combination with a c-Met-specific probe (red). DAPI (blue) was used as counterstain. Colon cancer with c-Met amplification detected by PCR-LDR, FISH analysis proves the gain in c-Met gene copy number.
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Fig 7a. The HSA domains from yeast modifying complexes RSC (Sth1), SWI-SNF (Snf2), SWR1 (Swr1), NuA4 (Eaf1), INO80 (Ino80) and human SWI-SNF (BRG1) nucleate binding of their respective ARPñARP or ARPñactin members.
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Fig 1. Flow diagram of basic steps involved in preplanning, intraoperative (IO) planning, and dynamic IO planning.
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Fig 3A. Endoscopic view of patient with Barrettís esophagus with high-grade dysplasia before endoscopic mucosal resection using the îband and snareî technique.
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Fig 2. Pie chart of known activating mutations in signaling molecules in lung adenocarcinoma.
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Fig 3. GFAP expression in an extra-axial ependymoma.
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Fig 1. Study enrollment.
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Fig 1B. Bone marrow cytospin from an ML Npm1+/ñ mouse showing blasts with intracytoplasmic vacuoles, high nuclear/cytoplasmic ratio, basophilic cytoplasm, and multiple nucleoli.
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Fig 7A. Native structure of 4-HBCRox showing the ligation pattern of Mo.
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Fig 1D. Chromogranin positivity in spindle tumor cells indicating their identity as chromaffin cells.
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Fig 2A. IL-10 controls T cell tolerance at the interface between the innate and the adaptive immune systems.
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Fig 3. TLE1 shows high sensitivity and specificity in SYT-SSX- positive synovial sarcomas, as tested on tissue microarrays. Inset: Strong nuclear labeling with anti-TLE1 antibody (Santa Cruz, polyclonal rabbit; M-101) 20.
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Fig 6. Long-term (9 month) follow-up after no revisions. Note good contour and hypertrophic scarring.
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Fig 1A. Cartoon surface representations of BF ternary structure.
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Fig 1. Calculating the Cancer Linker Degree (CLD) of a protein.
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Fig 1. Dermoscopic images used for patient evaluation.
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Fig 1. Instruments used in the Marian (greater) operation.
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Fig 4. In vivo imaging of transgene activity provides an index of biological enzyme function.
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Fig 6A. Accumulation of OT-I T cells in the liver was dependent on the antigen presentation capacity of cDCs.
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Fig 3D. 55-year-old man with newly diagnosed colorectal cancer. Fusion axial PET/CT (D) images from 18F-FDG PET/CT show increased FDG activity within numerous hepatic metastatic lesions (white arrow). Focus of increased activity deep in relation to left latissimus dorsi muscle within fatty-appearing lesion (black arrow) suggests hibernoma.
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Fig 6A. HUVEC monolayers were grown to confluence on fibronectin-coated slides and then treated for 24 hr with rhAngptl4.
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Fig 4B. Schematic representation of gene lists.
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Fig 2. Proposed synthesis of C2 oxygenated bridged pyrrolizidine core of the stemofoline alkaloids via inter- or intramolecular dipolar azomethine ylide cycloaddition.
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Fig 3. Striking EGFR protein up-regulation in metastases of MBC10.
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Fig 1C. Naevus with homogeneous pattern which lacks network and globules.
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Fig 1A. Lethally irradiated BALB/c mice were transplanted with syngeneic purified HS cells (or lin- bone marrow cells); control mice received HS cells only, the treatment group received additional T-cell precursors generated in OP9-DL1 cocultures.
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Fig 6. A model depicting the relationship of Fos, Jun, and selected kinase signaling pathways to cancer progression in the context of loss of function of Nkx3.1 and Pten.
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Fig 2. Biomarkers in the PI(3)KñPTENñmTOR pathway.
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Fig 2A-D. Zip4h expression in testis sections.
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Fig 1. Prostate cancer clinical-states model, a framework for patient management and drug development.
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Fig 1F-K. RNA in situ hybridization assays in whole mount at the stages indicated, using a mouse Spry2 probe.
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Fig 1. Geographical distribution of GOG study sites at which GOG-199 was open to enrollment.
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Fig 1C-H. Benign spindle-cell GISTs (Case 20 and Case 3) with KIT exon 13 (c) and KIT exon 17 (d) mutations. Malignant spindle-cell GISTs (Case 10 and Case 6) with KIT exon 13 (e) and exon 17 (f) mutations. Malignant epithelioid GISTs (Case 14 and Case 12) with KIT exon 13 (g) and KIT exon 17 (h) mutations.
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Fig 1. Osteoid osteoma ñ AP radiograph of the right foot demonstrates sclerosis of the proximal phalanx of the second toe.
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Fig 1A. Tertiary structures of cellular and poxvirus cap methyltransferases and a model of the Michaelis complex of the vaccinia virus enzyme.
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Fig 5. The left panel shows an H&E section of the TURP chips embedded in a paraffin block.
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Fig 3. Unrooted tree diagramming the relationship between the density-estimated Ramachandran distributions of the four secondary structure classes H (helix), E (sheet), C (coil), and T (turn).
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Fig 1. Typical high-grade serous carcinoma with a papillary pattern and high nuclear grade.
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Fig 1. Multifaceted Role of MMP-9 in Supporting Mobilization and Recruitment of Bone Marrow-Derived Cells in Tumor Vasculogenesis and Neoangiogenesis.
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Fig 1B. Antp immunodetection in (i) wild-type and (ii) brm2/pont wing discs.
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Fig 2. The steps involved in the process of gene correction of the mouse model of sickle cell anemia using induced pluripotent stem (iPS) cells.
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Fig 1A. Hypoxia in microscopic HT29.
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Fig 2. miR-279 is expressed in precursor cells in the developing MP.
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Fig 1. MicroRNAs mediate gene regulation through multiple mechanisms.
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Fig 2. Niche-to-niche migration of BM and tumor cells.
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Fig 4B. After two 5-mg doses of melphalan.
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Fig 2. Central plane view of two-dimensional brachytherapy implant dosimetric plan.
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Fig 2 Bottom. The case was adjudicated as atypical endometrial cells and surgical follow-up revealed an endometrial adenocarcinoma of endometrioid type.
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Fig 3A. In wild-type cells, the NHEJ apparatus is assembled at the DSB via contacts between the Ku homodimer (which encircles the DNA as a toroidal clamp) and the POL domain of LigD.
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Fig 3. Coronal CT, PET, and integrated PET/CT in 64-year-old man with epithelial malignant pleural mesothelioma show diffuse uptake of [18F]-fluoro-2-deoxy-d-glucose in primary right pleural tumor (SUV 11.6) and focus of increased uptake in 1.5 cm left gastric lymph node (arrow).
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Fig 1F. PGCs, HSCs, and blood progenitors in the zebrafish at not, vert, similar24ñ28 hours postfertilization.
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Fig 3A. Data from AJ SNPs; The number of SNPs with a positive DA value (excess homozygotes) is graphed above the zero line in each graph. The number of SNPs with a negative DA value is graphed below the zero line in each graph.
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Fig 1B. Modeling cell mechanics as an energy minimization problem; Schematic of a hypothetical energy landscape representing varying combinations of two parameters.
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Fig 4 Left. Interstitial pneumonia with lymphocytic infiltration associated with intraluminal proliferation.
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Fig 2B. Sagittal for Patient 1.
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![Fig 3. Coronal CT, PET, and integrated PET/CT in 64-year-old man with epithelial malignant pleural mesothelioma show diffuse uptake of [18F]-fluoro-2-deoxy-d-glucose in primary right pleural tumor (SUV 11.6) and focus of increased uptake in 1.5 cm left gastric lymph node (arrow).](https://library.mskcc.org/sparks/sparksimgs/graphics/sparks/archive/archive2008/LungCancer_Armato_mini.jpg)
