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2021-10-01

Fig 1. Profiling single T cells in NSCLC treated with neoadjuvant PD-1 blockade.

Fig 1. Profiling single T cells in NSCLC treated with neoadjuvant PD-1 blockade.
  • Caushi JX, Zhang J, Ji Z, Vaghasia A, Zhang B, Hsiue EH, Mog BJ, ... Smith KN

  • Nature. 2021 Aug;596(7870):126-132. doi: 10.1038/s41586-021-03752-4. Epub 2021 Jul 21.
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2021-10-04

Fig. 1. Predicted probability of any moderate or greater toxicity over time during and after treatment based on treatment type.

Fig. 1. Predicted probability of any moderate or greater toxicity over time during and after treatment based on treatment type.
  • Lapen K, Sabol C, Tin AL, Lynch K, Kassa A, Mabli X, Ford J, Cha E, Bernstein MB, Braunstein LZ, Cahlon O, Daly BM, Sandler K, McCloskey SA, Vickers AJ, Khan AJ, Gillespie EF

  • Int J Radiat Oncol Biol Phys. 2021 Jul 24. pii: S0360-3016(21)02562-1. doi: 10.1016/j.ijrobp.2021.07.1692.

2021-10-05

Fig 1. The NXF1 mRNA export pathway. The major pathway for mRNA export from the nucleus to the cytoplasm in metazoans is regulated by a heterodimeric receptor composed of the proteins NXF1 bound to NXT1.

Fig 1. The NXF1 mRNA export pathway. The major pathway for mRNA export from the nucleus to the cytoplasm in metazoans is regulated by a heterodimeric receptor composed of the proteins NXF1 bound to NXT1.
  • Wang E, Abdel-Wahab O

  • Cancer Discov. 2021 Sep;11(9):2129-2131. doi: 10.1158/2159-8290.CD-21-0862.

2021-10-06

Fig 1. Bladder cancer can be classified into various molecular subtypes based on gene expression profiling.

Fig 1. Bladder cancer can be classified into various molecular subtypes based on gene expression profiling.
  • Teo MY, Rosenberg JE

  • Clin Cancer Res. 2021 Sep 15;27(18):4950-4952. doi: 10.1158/1078-0432.CCR-21-1807. Epub 2021 Jul 19.

2021-10-07

Figure 5. Residues that interact with E2˜SUMO are mostly conserved between Siz2 and Siz1.

Figure 5. Residues that interact with E2˜SUMO are mostly conserved between Siz2 and Siz1.
  • Cappadocia L, Kochanczyk T, Lima CD

  • EMBO J. 2021 Sep 29:e103787. doi: 10.15252/embj.2019103787.

2021-10-08

Figure 4: Sankey diagrams of patients with (A) prostate, (B) colorectal, (C) breast, (D) lung, (E) kidney and bladder, and (F) pancreatic primary cancers and their most common first and second sites of metastasis to nodal (in green) and nonnodal (bone: purple; liver: red; lung: blue; peritoneum: yellow; pleura: orange) organs.

Figure 4: Sankey diagrams of patients with (A) prostate, (B) colorectal, (C) breast, (D) lung, (E) kidney and bladder, and (F) pancreatic primary cancers and their most common first and second sites of metastasis to nodal (in green) and nonnodal (bone: purple; liver: red; lung: blue; peritoneum: yellow; pleura: orange) organs.
  • Do RKG, Lupton K, Causa Andrieu PI, Luthra A, Taya M, Batch K, Nguyen H, Rahurkar P, Gazit L, Nicholas K, Fong CJ, Gangai N, Schultz N, Zulkernine F, Sevilimedu V, Juluru K, Simpson A, Hricak H

  • Radiology. 2021 Oct;301(1):115-122. doi: 10.1148/radiol.2021210043. Epub 2021 Aug 3.

2021-10-11

Fig 1 Adjusted overall survival for five years after landmark time points for first autologous haematopoietic cell transplantation in mantle cell lymphoma.

Fig 1 Adjusted overall survival for five years after landmark time points for first autologous haematopoietic cell transplantation in mantle cell lymphoma.
  • Riedell PA, Hamadani M, Ahn KW, Litovich C, Brunstein CG, Cashen AF, Cohen JB, Epperla N, Hill BT, Im A, Inwards DJ, Lister J, McCarty JM, Ravi Kiran Pingali S, Shadman M, Shaughnessy P, Solh M, Stiff PJ, Vose JM, Kharfan-Dabaja MA, Herrera AF, Sauter CS, Smith SM

  • Br J Haematol. 2021 Sep 28. doi: 10.1111/bjh.17865.

2021-10-12

Figure 2. Long-term United States and worldwide interest in search terms related to the diagnostic and therapeutic options of interventional radiology.

Figure 2. Long-term United States and worldwide interest in search terms related to the diagnostic and therapeutic options of interventional radiology.
  • Berning P, Maybody M, Deipolyi AR, Solomon SB, Dzaye O

  • J Vasc Interv Radiol. 2021 Oct;32(10):1445-1448.e1. doi: 10.1016/j.jvir.2021.07.005. Epub 2021 Jul 20.

2021-10-13

Figure. Overview of Data Sets and Studies.

Figure. Overview of Data Sets and Studies.
  • Daneshjou R, Smith MP, Sun MD, Rotemberg V, Zou J

  • JAMA Dermatol. 2021 Sep 22. pii: 2784295. doi: 10.1001/jamadermatol.2021.3129.

2021-10-14

Graphical abstract.

Graphical abstract.
  • Zhou M, Yuan M, Zhang M, Lei C, Aras O, Zhang X, An F

  • Eur J Med Chem. 2021 Sep 4;226:113825. doi: 10.1016/j.ejmech.2021.113825.

2021-10-15

Figure 1. Intestinal homeostasis is tightly controlled by gut microbiota through a large number of microbial metabolites/components.

Figure 1. Intestinal homeostasis is tightly controlled by gut microbiota through a large number of microbial metabolites/components.
  • Tang M, Li S, Wei L, Hou Z, Qu J, Li L

  • Front Immunol. 2021 Sep 14;12:684605. doi: 10.3389/fimmu.2021.684605. eCollection 2021.
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2021-10-18

Fig 2. Immunotype classification significantly correlates with survival in ICB-treated patients with melanoma.

Fig 2. Immunotype classification significantly correlates with survival in ICB-treated patients with melanoma.
  • Shen R, Postow MA, Adamow M, Arora A, Hannum M, Maher C, Wong P, Curran MA, Hollmann TJ, Jia L, Al-Ahmadie H, Keegan N, Funt SA, Iyer G, Rosenberg JE, Bajorin DF, Chapman PB, Shoushtari AN, Betof AS, Momtaz P, Merghoub T, Wolchok JD, Panageas KS, Callahan MK

  • Sci Transl Med. 2021 Aug 25;13(608). pii: 13/608/eabf5107. doi: 10.1126/scitranslmed.abf5107.

2021-10-19

Fig 1. 124I activity concentration in the phantom’s spheres as a function of increasing 131I activity in the background measured on the PET image reconstructed with the OSEM algorithm with 2 iterations and 16 subsets, TOF information and PSF modeling.

Fig 1. 124I activity concentration in the phantom’s spheres as a function of increasing 131I activity in the background measured on the PET image reconstructed with the OSEM algorithm with 2 iterations and 16 subsets, TOF information and PSF modeling.
  • Fanchon LM, Beattie BJ, Pentlow K, Larson SM, Humm JL

  • EJNMMI Phys. 2021 Jul 12;8(1):50. doi: 10.1186/s40658-021-00398-z.
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2021-10-20

Figure 3. OncoPrint plots of risk scores with mutational burden, sex, smoking status, asbestos exposure, histology, and mutation status for the top mutated genes.

Figure 3. OncoPrint plots of risk scores with mutational burden, sex, smoking status, asbestos exposure, histology, and mutation status for the top mutated genes.
  • Zauderer MG, Martin A, Egger J, Rizvi H, Offin M, Rimner A, Adusumilli PS, Rusch VW, Kris MG, Sauter JL, Ladanyi M, Shen R

  • Lancet Digit Health. 2021 Sep;3(9):e565-e576. doi: 10.1016/S2589-7500(21)00104-7. Epub 2021 Jul 28.
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2021-10-21

Figure 2. Exon-exon junctions reads.

Figure 2. Exon-exon junctions reads.
  • Vural S, Chang LC, Yee LM, Sonkin D

  • Sci Rep. 2021 Aug 26;11(1):17275. doi: 10.1038/s41598-021-96700-1.
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2021-10-22

Fig. 2: Building an integrative oncogene-dependency map of EGFRT790M/L858R, KRASG12V, and RIT1M90I

Fig. 2: Building an integrative oncogene-dependency map of EGFRT790M/L858R, KRASG12V, and RIT1M90I
  • Vichas A, Riley AK, Nkinsi NT, Kamlapurkar S, Parrish PCR, Lo A, Duke F, Chen J, Fung I, Watson J, Rees M, Gabel AM, Thomas JD, Bradley RK, Lee JK, Hatch EM, Baine MK, Rekhtman N, Ladanyi M, Piccioni F, Berger AH

  • Nat Commun. 2021 Aug 9;12(1):4789. doi: 10.1038/s41467-021-24841-y.
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2021-10-25

Figure 1. WBC count vs time (in months) with major events labeled.

Figure 1. WBC count vs time (in months) with major events labeled.
  • Chen JA, Hou Y, Roskin KM, Arber DA, Bangs CD, Baughn LB, Cherry AM, Ewalt MD, Fire AZ, Fresard L, Kearney HM, Montgomery SB, Ohgami RS, Pearce KE, Pitel BA, Merker JD, Gotlib J

  • Blood Adv. 2021 Sep 14;5(17):3492-3496. doi: 10.1182/bloodadvances.2020004174.
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2021-10-26

Visual Abstract.

Visual Abstract.
  • Herrera AF, Ahn KW, Litovich C, Chen Y, Assal A, Bashir Q, Bayer RL, Coleman M, DeFilipp Z, Farhadfar N, Greenwood M, Hahn T, Horwitz M, Jacobson C, Jaglowski S, Lachance S, Langston A, Mattar B, Maziarz RT, McGuirk J, Mian MAH, Nathan S, Phillips A, Rakszawski K, Sengeloev H, Shenoy S, Stuart R, Sauter CS, Kharfan-Dabaja MA, Hamadani M

  • Blood Adv. 2021 Sep 28;5(18):3528-3539. doi: 10.1182/bloodadvances.2021004865.
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2021-10-27

Figure 1. Four domains of research according to Patient-Centered Outcomes Research Institute.

Figure 1. Four domains of research according to Patient-Centered Outcomes Research Institute.
  • Cheung CK, Tucker-Seeley R, Davies S, Gilman M, Miller KA, Lopes G, Betz GD, Katerere-Virima T, Helbling LE, Thomas BN, Lewis MA

  • Future Oncol. 2021 Oct;17(28):3743-3756. doi: 10.2217/fon-2020-1213. Epub 2021 Jul 15.
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2021-10-28

Fig. 3. Absolute contralateral breast cancer risk by PRS percentiles per age category of the first breast cancer diagnosis for BRCA1 and BRCA2 heterozygotes.

Fig. 3. Absolute contralateral breast cancer risk by PRS percentiles per age category of the first breast cancer diagnosis for BRCA1 and BRCA2 heterozygotes.
  • Lakeman IMM, van den Broek AJ, Vos JAM, Barnes DR, Adlard J, Andrulis IL, Arason A, Arnold N,...Schmidt MK

  • Genet Med. 2021 Sep;23(9):1726-1737. doi: 10.1038/s41436-021-01198-7. Epub 2021 Jun 10.
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2021-10-29

Fig. 2. Magnetic resonance imaging (MRI) of histiocytoses of the nervous system.

Fig. 2. Magnetic resonance imaging (MRI) of histiocytoses of the nervous system.
  • Cohen Aubart F, Idbaih A, Emile JF, Amoura Z, Abdel-Wahab O, Durham BH, Haroche J, Diamond EL

  • Neuro Oncol. 2021 Sep 1;23(9):1433-1446. doi: 10.1093/neuonc/noab107.
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2021-11-01

Fig. 1. Maximal response to therapy by mutation status in patients with NSCLC.

Fig. 1. Maximal response to therapy by mutation status in patients with NSCLC.
  • Gutierrez M, Guo R, Giaccone G, Liu SV, Hao Z, Hilton C, Hinson JM Jr, Kris MG, Orlemans EO, Drilon A

  • Lung Cancer. 2021 Oct 8;162:23-28. doi: 10.1016/j.lungcan.2021.10.001.