Return to Today's science sparks archives

Information Click the tweet icon above each article title to share it on Twitter.

2020-11-02

FIGURE 3: Pathology from uterine biopsy. Hematoxylin-eosin–stained slide.

FIGURE 3: Pathology from uterine biopsy. Hematoxylin-eosin–stained slide.
  • Causa Andrieu PI, Das JP, Woo S, Ryan R, Akin O, Ulaner GA

  • Clin Nucl Med. 2020 Nov;45(11):873-875.

2020-11-03

Fig.1 COMIDA implementation approaches targeting predisposing and enabling factors in the behavioral model of vulnerable populations.

Fig.1 COMIDA implementation approaches targeting predisposing and enabling factors in the behavioral model of vulnerable populations.
  • Leng J, Costas-Muniz R, Pelto D, Flores J, Ramirez J, Lui F, Tonda J, Gany F

  • J Community Health. 2020 Oct 7. pii: 10.1007/s10900-020-00933-6. doi: 10.1007/s10900-020-00933-6.

2020-11-04

Fig.1. Overview about radiation-induced acute and subacute alveolar changes.

Fig.1. Overview about radiation-induced acute and subacute alveolar changes.
  • Kasmann L, Dietrich A, Staab-Weijnitz CA, Manapov F, Behr J, Rimner A, Jeremic B, Senan S, De Ruysscher D, Lauber K, Belka C

  • Radiat Oncol. 2020 Sep 10;15(1):214.
Open Access button

2020-11-05

Fig. 2. Homozygous Smpd1 deficiency abrogates, whereas heterozygous Smpd1 deficiency moderately reduces Asm activity.

Fig. 2. Homozygous Smpd1 deficiency abrogates, whereas heterozygous Smpd1 deficiency moderately reduces Asm activity.
  • Hagemann N, Mohamud Yusuf A, Martiny C, Zhang X, Kleinschnitz C, Gunzer M, Kolesnick R, Gulbins E, Hermann DM

  • Basic Res Cardiol. 2020 Oct 14;115(6):64.
Open Access button

2020-11-06

Fig. 2 Distribution of inter-tumoral mismatch repair protein immunohistochemistry discordances among Lynch syndrome patients, patients with non-Lynch syndrome colorectal cancer predisposing syndromes, and patients with sporadic or likely sporadic gastrointestinal tract cancers

Fig. 2 Distribution of inter-tumoral mismatch repair protein immunohistochemistry discordances among Lynch syndrome patients, patients with non-Lynch syndrome colorectal cancer predisposing syndromes, and patients with sporadic or likely sporadic gastrointestinal tract cancers
  • Vyas M, Firat C, Hechtman JF, Weiser MR, Yaeger R, Vanderbilt C, Benhamida JK, Keshinro A, Zhang L, Ntiamoah P, Gonzalez M, Andrade R, El Dika I, Markowitz AJ, Smith JJ, Garcia-Aguilar J, Vakiani E, Klimstra DS, Stadler ZK, Shia J

  • Fam Cancer. 2020 Oct 9. pii: 10.1007/s10689-020-00210-4. doi: 10.1007/s10689-020-00210-4.

2020-11-09

Fig 2. The capture of all head and neck subsites, across all domains, independent of the primary treatment modality was accomplished using a system based on the 10th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD‐10) codes.

Fig 2. The capture of all head and neck subsites, across all domains, independent of the primary treatment modality was accomplished using a system based on the 10th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD‐10) codes.
  • Strachna O, Cohen MA, Allison MM, Pfister DG, Lee NY, Wong RJ, McBride SM, Mohammed RR, Kemeny E, Polubriaginof FCG, Kassa A, Hannon M, Cracchiolo JR

  • Cancer. 2020 Oct 27.

2020-11-10

Fig 1. The structures of the Fred Hutchinson Cancer Research Center (FHCRC) model and the Erasmus University Medical Center-MIcrosimulation SCreening ANalysis (Erasmus-MISCAN) model. PSA = prostate-specific antigen.

Fig 1. The structures of the Fred Hutchinson Cancer Research Center (FHCRC) model and the Erasmus University Medical Center-MIcrosimulation SCreening ANalysis (Erasmus-MISCAN) model. PSA = prostate-specific antigen.
  • Heijnsdijk EAM, Gulati R, Tsodikov A, Lange JM, Mariotto AB, Vickers AJ, Carlsson SV, Etzioni R

  • J Natl Cancer Inst. 2020 Oct 1;112(10):1013-1020.
Open Access button

2020-11-11

Fig 1. Mechanism of action figure

Fig 1. Mechanism of action figure
  • Laskin J, Liu SV, Tolba K, Heining C, Schlenk RF, Cheema P, Cadranel J, Jones MR, Drilon A, Cseh A, Gyorffy S, Solca F, Duruisseaux M

  • Ann Oncol. 2020 Sep 9:S0923-7534(20)42427-5.
Open Access button

2020-11-12

Fig. 4. IDH2 protein sequence in the proximity of codon R172 is remarkably similar to the IDH1 protein sequence around codon R132.

Fig. 4. IDH2 protein sequence in the proximity of codon R172 is remarkably similar to the IDH1 protein sequence around codon R132.
  • Dogan S, Frosina D, Geronimo JA, Hernandez E, Mohanty A, Bale T, Hechtman JF, Arcila ME, Hameed MR, Jungbluth AA

  • Hum Pathol. 2020 Oct 2;106:45-53. doi: 10.1016/j.humpath.2020.09.013.

2020-11-13

Fig 1. Blockage of TGF-β signalling in CD4+ T cells suppresses tumour development independently of CD8+ T cells.

Fig 1. Blockage of TGF-β signalling in CD4+ T cells suppresses tumour development independently of CD8+ T cells.
  • Liu M, Kuo F, Capistrano KJ, Kang D, Nixon BG, Shi W, Chou C, Do MH, Stamatiades EG, Gao S, Li S, Chen Y, Hsieh JJ, Hakimi AA, Taniuchi I, Chan TA, Li MO

  • Nature. 2020 Nov;587(7832):115-120.

2020-11-16

Fig. 4. Unsupervised clustering based on the delta values of the paired samples.

Fig. 4. Unsupervised clustering based on the delta values of the paired samples.
  • Garrido-Castro AC, Saura C, Barroso-Sousa R, Guo H, Ciruelos E, Bermejo B, Gavila J, Serra V, Prat A, Pare L, Celiz P, Villagrasa P, Li Y, Savoie J, Xu Z, Arteaga CL, Krop IE, Solit DB, Mills GB, Cantley LC, Winer EP, Lin NU, Rodon J

  • Breast Cancer Res. 2020 Nov 2;22(1):120. doi: 10.1186/s13058-020-01354-y.
Open Access button

2020-11-17

Graphical Abstract

Graphical Abstract
  • Lee C, Lamech L, Johns E, Overholtzer M

  • Dev Cell. 2020 Nov 9;55(3):289-297.e4. doi: 10.1016/j.devcel.2020.08.008. Epub 2020 Sep 10.

2020-11-18

Fig 5. Lethality of asp1-(W386-Stop) and asp1-(W493-Stop) is suppressed by CPF and Rhn1 mutations. Serial 5-fold dilutions of the indicated strains were spot tested for growth at the indicated temperatures.

Fig 5. Lethality of asp1-(W386-Stop) and asp1-(W493-Stop) is suppressed by CPF and Rhn1 mutations. Serial 5-fold dilutions of the indicated strains were spot tested for growth at the indicated temperatures.
  • Garg A, Shuman S, Schwer B

  • Nucleic Acids Res. 2020 Nov 4;48(19):10739-10752. doi: 10.1093/nar/gkaa776.
Open Access button

2020-11-19

Fig 5. Lineage-Specific Dynamics of ERK Activity in ICM Cells.

Fig 5. Lineage-Specific Dynamics of ERK Activity in ICM Cells.
  • Simon CS, Rahman S, Raina D, Schroter C, Hadjantonakis AK

  • Dev Cell. 2020 Nov 9;55(3):341-353.e5. doi: 10.1016/j.devcel.2020.09.030. Epub 2020 Oct 21.

2020-11-20

Fig 1. Blocking PD-1 and PD-L1 Interaction in the Tumor-Draining Lymph Node (TDLN) Confers Anti-tumor Effects

Fig 1. Blocking PD-1 and PD-L1 Interaction in the Tumor-Draining Lymph Node (TDLN) Confers Anti-tumor Effects
  • Brown CC, Wolchok JD

  • Cancer Cell. 2020 Nov 9;38(5):615-617. doi: 10.1016/j.ccell.2020.10.017.

2020-11-23

Fig 4. RNA exosome-associated proteins in human disease.

Fig 4. RNA exosome-associated proteins in human disease.
  • Weick EM, Lima CD

  • Curr Opin Struct Biol. 2020 Nov 1;67:86-94. doi: 10.1016/j.sbi.2020.09.010.
Open Access button

2020-11-24

Figure S1. ST2 expression on T cells promotes antiviral T cell response against LCMV.

Figure S1. ST2 expression on T cells promotes antiviral T cell response against LCMV.
  • Hemmers S, Schizas M, Rudensky AY

  • J Exp Med. 2021 Feb 1;218(2). pii: 211487. doi: 10.1084/jem.20201234.

2020-11-25

Fig 1. A 21-year-old man presented with a 4-month history of painless swelling in the left upper limb.

Fig 1. A 21-year-old man presented with a 4-month history of painless swelling in the left upper limb.
  • Das JP, Riedl CC, Ulaner GA

  • Clin Nucl Med. 2020 Dec;45(12):989-991. doi: 10.1097/RLU.0000000000003299.

2020-11-27

Figure 3 Comparison of breast neuroendocrine tumours (NETs) to oestrogen receptor-positive/HER2-negative breast cancer and NETs of other organ systems.

Figure 3 Comparison of breast neuroendocrine tumours (NETs) to oestrogen receptor-positive/HER2-negative breast cancer and NETs of other organ systems.
  • Pareja F, Vahdatinia M, Marchio C, Lee SSK, Da Cruz Paula A, Derakhshan F, da Silva EM, Selenica P, Dopeso H, Chandarlapaty S, Wen HY, Vincent-Salomon A, Brogi E, Weigelt B, Reis-Filho JS

  • J Clin Pathol. 2020 Nov 4. pii: jclinpath-2020-207052. doi: 10.1136/jclinpath-2020-207052.

2020-11-30

Fig. 1. Program Director Response to Likert Scale Questions.

Fig. 1. Program Director Response to Likert Scale Questions.
  • Hill MV, Ross EA, Crawford D, Lai L, Turaga K, Grubbs EG, Mullen J, Dineen S, D'Angelica M, Reddy S, Farma JM

  • Am J Surg. 2020 Nov 9. pii: S0002-9610(20)30730-3. doi: 10.1016/j.amjsurg.2020.11.007.

2020-12-01

Visual Abstract.

Visual Abstract.
  • van der Ploeg K, Le Luduec JB, Stevenson PA, Park S, Gooley TA, Petersdorf EW, Shaffer BC, Hsu KC

  • Blood Adv. 2020 Oct 13;4(19):4955-4964.
Open Access button