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Home Today's science sparks archives
 Today's science sparks archives - October to December 2006

Today's science sparks archives - October to December 2006

This page contains images and links to articles previously featured.

December 29, 2006

Comparison of dose distributions in the axial and coronal planes is shown for a cavernous sinus patient...

Comparison of dose distributions in the axial and coronal planes is shown for a cavernous sinus patient...

  • Yenice KM, Narayana A, Chang J, Gutin PH, Amols HI

  • Int J Radiat Oncol Biol Phys.
    2006 Nov 15;66(4 Suppl):S95-S101.

December 28, 2006

Synthesis of the Branched Trisaccharide and Its Conjugation to Quillaic Acid

Synthesis of the Branched Trisaccharide and Its Conjugation to Quillaic Acid

  • Kim YJ, Wang P, Navarro-Villalobos M, Rohde BD, Derryberry J, Gin DY

  • J Am Chem Soc.
    2006 Sep 13;128(36):11906-15.

December 27, 2006

Figure 1. Reversible membrane binding of lipid-modified proteins.

Figure 1. Reversible membrane binding of lipid-modified proteins.

  • Resh MD

  • Nat Chem Biol.
    2006 Nov;2(11):584-90.

December 22, 2006

Fig. 3. Phagocytosis and bacterial clearance by WT hemocytes.

Fig. 3. Phagocytosis and bacterial clearance by WT hemocytes.

  • Matova N, Anderson KV

  • Proc Natl Acad Sci U S A.
    2006 Oct 31;103(44):16424-9.

December 21, 2006

Immunohistochemical analysis of periostin (POSTN), IL8 and cartilage oligomeric matrix protein (COMP).

Immunohistochemical analysis of periostin (POSTN), IL8 and cartilage oligomeric matrix protein (COMP).

  • Grigoriadis A, Mackay A, Reis-Filho JS, Steele D, Iseli C, Stevenson BJ, Jongeneel CV, Valgeirsson H, Fenwick K, Iravani M, Leao M, Simpson AJ, Strausberg RL, Jat PS, Ashworth A, Neville AM, O'hare MJ

  • Breast Cancer Res.
    2006 Oct 2;8(5):R56

December 20, 2006

Fig 2. BAFF induces selective changes in gene transcription.

Fig 2. BAFF induces selective changes in gene transcription.

  • Patke A, Mecklenbrauker I, Erdjument-Bromage H,
    Tempst P, Tarakhovsky A

  • J Exp Med.
    2006 Oct 30;203(11):2551-62.

December 19, 2006

NV1066 selectively infects pleural, mediastinal, and diaphragmatic mesothelioma and spares normal tissue.

NV1066 selectively infects pleural, mediastinal, and diaphragmatic mesothelioma and spares normal tissue.

  • Adusumilli PS, Eisenberg DP, Stiles BM, Chung S, Chan MK, Rusch VW, Fong Y

  • J Thorac Cardiovasc Surg.
    2006 Nov;132(5):1179-88.

December 18, 2006

Pcsgs m+z mutant embryos display defects in muscle development, mesodermal patterning, segmentation, and early patterning events.

Pcsgs m+z mutant embryos display defects in muscle development, mesodermal patterning, segmentation, and early patterning events.

  • Beckett K, Baylies MK

  • Dev Biol.
    2006 Nov 1;299(1):176-92.

December 14, 2006

Fig 1. CD40 signaling regulates angiogenesis.

Fig 1. CD40 signaling regulates angiogenesis.

  • Bergmann S, Pandolfi PP

  • J Exp Med.
    2006 Oct 30;203(11):2409-12.

December 13, 2006

Fig 5. Phage lambda cI self-regulation kinetics.

Fig 5. Phage lambda cI self-regulation kinetics.

  • Saiz L, Vilar JM

  • Mol Syst Biol.
    2006;2:2006.0024.

December 12, 2006

Chest roentgenogram showing (A) the tracheostomy tube with migration of (B) the tracheal stents into the right main bronchus with resultant left-sided atelectasis.

Chest roentgenogram showing (A) the tracheostomy tube with migration of (B) the tracheal stents into the right main bronchus with resultant left-sided atelectasis.

  • Voigt LP, Hmidi A, Pastores SM, Maki RG, Carlson DL, Bains MS, Halpern NA

  • Ann Thorac Surg.
    2006 Nov;82(5):1898-900.

December 11, 2006

Fig 1. Phylogeny of VSIG4 and hypothetical models of its role as a T cell inhibitor.

Fig 1. Phylogeny of VSIG4 and hypothetical
models of its role as a T cell inhibitor.

  • Zang X, Allison JP

  • J Clin Invest.
    2006 Oct;116(10):2590-3.

December 8, 2006

Fig. 4. We determined if VEGF receptors Flk-1 and Flt-1 are required for VEGF-induced cardiomyocyte differentiation.

Fig. 4. We determined if VEGF receptors Flk-1 and Flt-1 are required for VEGF-induced cardiomyocyte differentiation.

  • Chen Y, Amende I, Hampton TG, Yang Y, Ke Q, Min JY, Xiao YF, Morgan JP

  • Am J Physiol Heart Circ Physiol.
    2006 Oct;291(4):H1653-8.

December 7, 2006

Fig 2. Proposed effects of the diYA and the diYF mutation on β1 integrins.

Fig 2. Proposed effects of the diYA and
the diYF mutation on β1 integrins.

  • Pylayeva Y, Giancotti FG

  • Genes Dev.
    2006 May 1;20(9):1057-60.

December 6, 2006

FIG 3. Migration and growth of GFP melanoma cells on the chick CAM, 10 days after inoculation.

FIG 3. Migration and growth of GFP melanoma cells on the chick CAM, 10 days after inoculation.

  • Lugassy C, Vernon SE, Busam K, Engbring JA, Welch DR, Poulos EG, Kleinman HK, Barnhill RL

  • Am J Dermatopathol.
    2006 Jun;28(3):187-93.

December 5, 2006

T4 RNA ligase 1 (Rnl1) is a tRNA repair enzyme that circumvents an RNA-damaging host antiviral response.

T4 RNA ligase 1 (Rnl1) is a tRNA
repair enzyme that circumvents an
RNA-damaging host antiviral response.

  • Wang LK, Schwer B, Shuman S

  • RNA.
    2006 Dec;12(12):2126-34.

December 4, 2006

FIGURE 4. Effects of the seed lesion region of interest (ROI) on the segmentation results.

FIGURE 4. Effects of the seed lesion region of interest (ROI) on the segmentation results.

  • Zhao B, Schwartz LH, Jiang L, Colville J, Moskowitz C, Wang L, Leftowitz R, Liu F, Kalaigian J

  • Invest Radiol.
    2006 Oct;41(10):753-62.

December 1, 2006

Fig. 2. Bmp pathway gene expression in developing bat limbs.

Fig. 2. Bmp pathway gene expression in developing bat limbs.

  • Weatherbee SD, Behringer RR, Rasweiler JJ, Niswander LA

  • Proc Natl Acad Sci U S A.
    2006 Oct 10;103(41):15103-7.

November 30, 2006

FIGURE 1. The MBC is a noninvasive device used for rigid patient immobilization.

FIGURE 1. The MBC is a noninvasive device
used for rigid patient immobilization.

  • Wright JL, Lovelock DM, Bilsky MH, Toner S, Zatcky J, Yamada Y

  • Am J Clin Oncol.
    2006 Oct;29(5):495-502.

November 29, 2006

Fig. 5. Epithelial–stromal competition model of androgen independence

Fig. 5. Epithelial–stromal competition model of androgen independence

  • Gao H, Ouyang X, Banach-Petrosky WA, Gerald WL, Shen MM, Abate-Shen C

  • Proc Natl Acad Sci U S A.
    2006 Sep 26;103(39):14477-82.

November 28, 2006

FIG. 9. Sample illustration of polygonograms

FIG. 9. Sample illustration of polygonograms

  • Chou TC

  • Pharmacol Rev.
    2006 Sep;58(3):621-81.

November 27, 2006

FIG 2. PML can recruit Chk2 into the PML NBs.

FIG 2. PML can recruit Chk2 into the PML NBs.

  • Yang S, Jeong JH, Brown AL, Lee CH, Pandolfi PP, Chung JH, Kim MK

  • J Biol Chem.
    2006 Sep 8;281(36):26645-54.

November 24, 2006

Fig. 1. Regulation of HIF-1{alpha} synthesis and stability.

Fig. 1. Regulation of HIF-1{alpha}
synthesis and stability.

  • Serganova I, Humm J, Ling C, Blasberg R

  • Clin Cancer Res.
    2006 Sep 15;12(18):5260-4.

November 22, 2006

Figure 4. N-myc is essential for the hyperplasia and tumorigenesis induced by deregulated Shh signaling.

Figure 4. N-myc is essential for the hyperplasia and tumorigenesis induced by deregulated Shh signaling.

  • Hatton BA, Knoepfler PS, Kenney AM, Rowitch DH, de Alboran IM, Olson JM, Eisenman RN

  • Cancer Res.
    2006 Sep 1;66(17):8655-61.

November 20, 2006

Histological response of GIST lesions in KitV558{Delta}/+ mice to imatinib treatment.

Histological response of GIST lesions in KitV558{Delta}/+ mice to imatinib treatment.

  • Rossi F, Ehlers I, Agosti V, Socci ND, Viale A, Sommer G, Yozgat Y, Manova K, Antonescu CR, Besmer P

  • Proc Natl Acad Sci U S A.
    2006 Aug 22;103(34):12843-8.

November 17, 2006

Microphotograph of an axial section of the kidneys demonstrates the gelatin sponge (arrow) in the renal parenchyma tissue.

Microphotograph of an axial section of the kidneys demonstrates the gelatin sponge (arrow) in the renal parenchyma tissue.

  • Permpongkosol S, Nicol TL, Bagga HS, Kohanim S, Kavoussi L, Solomon SB

  • J Vasc Interv Radiol.
    2006 Sep;17(9):1505-9.

November 16, 2006

3D time-lapse of a gastrula-stage embryo expressing a membrane targeted fluorescent pretein in all cells.

3D time-lapse of a gastrula-stage
embryo expressing a membrane targeted fluorescent pretein in all cells.

  • Di Gregorio A, Hadjantonakis AK

  • Bioessays.
    2006 Sep;28(9):874-9.

November 15, 2006

ADAM12 overexpression in mouse models for prostate, breast and intestinal tumors.

ADAM12 overexpression in mouse models for prostate, breast and intestinal tumors.

  • Peduto L, Reuter VE, Sehara-Fujisawa A, Shaffer DR, Scher HI, Blobel CP

  • Oncogene.
    2006 Aug 31;25(39):5462-6.

November 14, 2006

Fig. 3. Calcitonin positivity in C-cell hyperplasia.

Fig. 3. Calcitonin positivity in C-cell hyperplasia.

  • Shaha AR, Cohen T, Ghossein R, Tuttle RM

  • Laryngoscope.
    2006 Sep;116(9):1704-7.

November 13, 2006

Id4 expression in DCIS.

Id4 expression in DCIS.

  • de Candia P, Akram M, Benezra R, Brogi E

  • Hum Pathol.
    2006 Aug;37(8):1032-41.

November 10, 2006

Fig. 1. T-cell activation requires 2 independent signals

Fig. 1. T-cell activation requires 2 independent signals

  • Thompson RH, Allison JP, Kwon ED

  • Urol Oncol.
    2006 Sep-Oct;24(5):442-7.

November 9, 2006

Figure 4. PALB2 Plays a Critical Role...

Figure 4. PALB2 Plays a Critical Role...

  • Xia B, Sheng Q, Nakanishi K, Ohashi A, Wu J, Christ N, Liu X, Jasin M, Couch FJ, Livingston DM

  • Molecular Cell.
    2006 Jun 23;22(6):719-29.

November 8, 2006

Location of the guanosine residues chosen for the 2'-methylseleno modifications (circled in red) in the structures of the nonmodified duplex RNAs, 12-mer19 and 16-mer20

Location of the guanosine residues chosen for the 2'-methylseleno modifications (circled in red) in the structures of the nonmodified duplex RNAs, 12-mer19 and 16-mer20

  • Moroder H, Kreutz C, Lang K, Serganov A, Micura R

  • J Am Chem Soc.
    2006 Aug 2;128(30):9909-18.

November 7, 2006

Figure 2. Morphology of isolated cells on the smears

Figure 2. Morphology of isolated cells
on the smears

  • Reid-Nicholson MD, Tong G, Cangiarella JF, Moreira AL

  • Cancer. 2006 Aug 25;108(4):222-30.

November 6, 2006

Figure 2.Development of resistance in osteosarcoma (OS)

Figure 2.Development of resistance in osteosarcoma (OS)

  • Chou AJ, Gorlick R

  • Expert Rev Anticancer Ther. 2006 Jul;6(7):1075-85.

November 3, 2006

Figure 1. Small-Cell Lung Cancer

Figure 1. Small-Cell Lung Cancer

  • Zakowski MF, Ladanyi M, Kris MG

  • N Engl J Med. 2006 Jul 13;355(2):213-5.

November 2, 2006

Contrast-enhanced sagittal MRI of the brain reveals a heterogeneously enhancing and partially cystic suprasellar mass, principally located within the confines of the third ventricle

Contrast-enhanced sagittal MRI of the brain reveals a heterogeneously enhancing and partially cystic suprasellar mass, principally located within the confines of the third ventricle

  • Luther N, Edgar MA, Dunkel IJ, Souweidane MM

  • J Neurooncol. 2006 Aug;79(1):45-50.

November 1, 2006

Figure 5. Multicellular Rosette Formation in Intercalating Cells

Figure 5. Multicellular Rosette Formation in Intercalating Cells

  • Blankenship JT, Backovic ST, Sanny JS, Weitz O, Zallen JA

  • Dev Cell. 2006 Oct;11(4):459-70.

October 31, 2006

Fig. 2. Pericardial and diaphragmatic reconstruction.

The overall structure of WDR5 complexes with histone H3

  • Ruthenburg AJ, Wang W, Graybosch DM, Li H, Allis CD, Patel DJ, Verdine GL

  • Nat Struct Mol Biol. 2006 Aug;13(8):704-12.

October 30, 2006

Fig. 2. Pericardial and diaphragmatic reconstruction.

Fig. 2. Pericardial and diaphragmatic reconstruction.

  • Flores RM, Su W, Lal D, Rusch VW, La Quaglia MP

  • J Pediatr Surg. 2006 Oct;41(10):1738-42.

October 27, 2006

Morphogenetic defects in Nap1khlo mutant embryos

Morphogenetic defects in Nap1khlo mutant embryos

  • Rakeman AS, Anderson KV

  • Development. 2006 Aug;133(16):3075-83.

October 25, 2006

Gvax/anti-CTLA4 combination therapy induces tumor infiltration and rejection without permanently impairing Treg function.

Gvax/anti-CTLA4 combination therapy induces tumor infiltration and rejection without permanently impairing Treg function.

  • Quezada SA, Peggs KS, Curran MA, Allison JP

  • J Clin Invest. 2006 Jul;116(7):1935-45.

October 24, 2006

Fig. 2. Immunohistochemical staining patterns for CTAs...

Fig. 2. Immunohistochemical staining patterns for CTAs...

  • Sharma P, Shen Y, Wen S, Bajorin DF, Reuter VE, Old LJ, Jungbluth AA

  • Clin Cancer Res.2006 Sep 15;12(18):5442-7.

October 23, 2006

Selected protein protein interactions of BRCA1.ATF

Selected protein protein interactions of BRCA1.ATF

  • Goldberg JI, Borgen PI

  • Expert Rev Anticancer Ther. 2006 Aug;6(8):1205-14.

October 20, 2006

JNK pathway mutations block antimicrobial peptide gene expression in larval fat body tissue.

JNK pathway mutations block antimicrobial peptide gene expression in larval fat body tissue.

  • Delaney JR, Stoven S, Uvell H, Anderson KV, Engstrom Y, Mlodzik M

  • EMBO J. 2006 Jul 12;25(13):3068-77.

October 19, 2006

Reduction in migration after Dcx knockdown is cell autonomous as well as non-cell autonomous.

Reduction in migration after Dcx knockdown is cell autonomous as well as non-cell autonomous.

  • Ocbina PJ, Dizon ML, Shin L, Szele FG

  • Mol Cell Neurosci. 2006 Oct;33(2):126-35.

October 18, 2006

Fig. 1. Locking perineal template with catheters.

Fig. 1. Locking perineal template with catheters.

  • Yamada Y, Bhatia S, Zaider M, Cohen G, Donat M, Eastham J, Rabbani F, Schupak K, Lee J, Mueller B, Zelefsky MJ

  • Brachytherapy 2006 Jul-Sep;5(3):157-64.

October 17, 2006

Overexpression of JHDM3A antagonizes HP1 recruitment to pericentric heterochromatin.

Overexpression of JHDM3A antagonizes HP1 recruitment to pericentric heterochromatin.

  • Klose RJ, Yamane K, Bae Y, Zhang D, Erdjument-Bromage H, Tempst P, Wong J, Zhang Y

  • Nature 2006 Jul 20;442(7100):312-6.

October 16, 2006

Figure 3. The DNA strand exchange reaction.

Figure 3. The DNA strand exchange reaction.

  • Neale MJ, Keeney S

  • Nature 2006 Jul 13;442(7099):153-8.

October 13, 2006

Computed tomographic scan of the chest showing a large, right-sided posterior mediastinal mass

Computed tomographic scan
of the chest showing a large,
right-sided posterior mediastinal mass

  • Park BJ, Carrasquillo J, Bains MS, Flores RM

  • Ann Thorac Surg 2006 Jul;82(1):340-2.

October 12, 2006

Figure 2. Ex Vivo Analysis of Epithelial Adhesion and Polarity

Figure 2. Ex Vivo Analysis of Epithelial Adhesion and Polarity

  • Guo W, Pylayeva Y, Pepe A, Yoshioka T, Muller WJ, Inghirami G, Giancotti FG

  • Cell. 2006 Aug 11;126(3):489-502.

October 11, 2006

Cultured neuronal networks

Cultured neuronal networks

  • Khan RB, Gutin PH, Rai SN, Zhang L, Krol G, DeAngelis LM

  • Neurosurgery 2006 Jul;59(1):60-6; discussion 60-6.

October 10, 2006

Figure 2. Crossover Homeostasis Occurs at the Expense of Noncrossovers

Figure 2. Crossover Homeostasis
Occurs at the Expense of Noncrossovers

  • Martini E, Diaz RL, Hunter N, Keeney S

  • Cell 2006 Jul 28;126(2):285-95.

October 9, 2006

Separase has both proteolytic and non-proteolytic roles during meiosis I in vertebrate oocytes.

Separase has both proteolytic and
non-proteolyticroles during meiosis I
in vertebrate oocytes.

  • Terret ME, Jallepalli PV

  • Nat Cell Biol 2006 Sep;8(9):910-1.

October 5, 2006

FIGURE 3. NV1066-guided GFP-mediated fluorescent detection of lymph node metastases.

FIGURE 3. NV1066-guided GFP-mediated fluorescent detection of lymph node metastases.

  • Eisenberg DP, Adusumilli PS, Hendershott KJ, Chung S, Yu Z, Chan MK, Hezel M, Wong RJ, Fong Y

  • Ann Surg. 2006 Jun;243(6):824-30; discussion 830-2.

October 4, 2006

Hierarchical cluster analysis of differentially expressed genes in blood from patients with bladder cancer compared with patients with testicular and kidney cancer.

Hierarchical cluster analysis of differentially expressed genes in blood from patients with bladder cancer compared with patients with testicular and kidney cancer.

  • Osman I, Bajorin DF, Sun TT, Zhong H, Douglas D, Scattergood J, Zheng R, Han M, Marshall KW, Liew CC

  • Clinical Cancer Research 2006 Jun 1;12(11 Pt 1):3374-80.

October 3, 2006

Figure 2. Catheter placement in a patient with low bile duct obstruction.

Figure 2. Catheter placement in a patient with low bile duct obstruction.

  • Covey AM, Brown KT

  • Journal of Supportive Oncology 2006 Jun;4(6):269-73.

October 2, 2006

FIGURE 4. Transaxial and coronal PET/CT images (Siemens Biograph LSO, Erlangen, Germany) with 15 mCi of F-18 FDG demonstrating a large mass in the posterior mediastinum with increased FDG uptake (maximum SUV = 4.9).

Transaxial and coronal PET/CT images with 15 mCi of F-18 FDG demonstrating a large mass in the posterior mediastinum with increased FDG uptake (maximum SUV = 4.9)

  • Meirelles GS, Ravizzini G, Yeung HW, Akhurst T.

  • Clin Nucl Med.2006 Jun;31(6):342-4.
Content editor, Sarah Jewell
Last revised: July 6, 2008 2:25 PM EST

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