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 Today's science sparks archives - September 2008

Today's science sparks archives - September 2008

This page contains images and links to articles previously featured.

September 30, 2008

Fig 3b. Adipose tissue response to leptin treatment and withdrawal.

Fig 3b. Adipose tissue response to leptin treatment and withdrawal.
    Birsoy K, Soukas A, Torrens J, Ceccarini G, Montez J, Maffei M, Cohen P, Fayzikhodjaeva G, Viale A, Socci ND, Friedman JM

  • Proc Natl Acad Sci U S A.
    2008 Sep 2;105(35):12985-90.

September 29, 2008

Fig 1. Domain organization of M. smegmatis UvrD2.

Fig 1. Domain organization of M. smegmatis UvrD2.
    Sinha KM, Stephanou NC, Unciuleac MC, Glickman MS, Shuman S

  • Biochemistry.
    2008 Sep 9;47(36):9355-64.

September 26, 2008

Fig 1. Orthogonal film based implant evaluation. Surgical clips identified for cavity delineation and dummy sources were placed in catheters for subsequent position digitization.

Fig 1. Orthogonal film based implant evaluation. Surgical clips identified for cavity delineation and dummy sources were placed in catheters for subsequent position digitization.
    Arthur DW, Winter K, Kuske RR, Bolton J, Rabinovitch R, White J, Hanson WF, Wilenzick RM, McCormick B

  • Int J Radiat Oncol Biol Phys.
    2008 Oct 1;72(2):467-73.

September 25, 2008

Fig. 3b. Covariation of CD8 and SHP-1 levels limits the frequencies of hypo- and hyperresponsive cells. Computer model for T cell activation demonstrate how the EC50 for ppERK responsiveness is determined by both CD8 and SHP-1 levels.

Fig. 3b. Covariation of CD8 and SHP-1 levels limits the frequencies of hypo- and hyperresponsive cells. Computer model for T cell activation demonstrate how the EC50 for ppERK responsiveness is determined by both CD8 and SHP-1 levels.
    Xing L, Deng X, Kotedia K, Ackerstaff E, Ponomarev V, Clifton Ling C, Koutcher JA, Li GC

  • Science.
    2008 Aug 22;321(5892):1081-4.

September 24, 2008

Fig 1d. Fusion protein expression in transiently tranfected Cos7 cells and stably transfected R3327-CD/mDsRed or R3327-CD/UPRT/mDsRed cells

Fig 1d. Fusion protein expression in transiently tranfected Cos7 cells and stably transfected R3327-CD/mDsRed or R3327-CD/UPRT/mDsRed cells
    Xing L, Deng X, Kotedia K, Ackerstaff E, Ponomarev V, Clifton Ling C, Koutcher JA, Li GC

  • Acta Oncol.
    2008;47(7):1211-20.

September 23, 2008

Fig 8a. siRNA-mediated depletion of hChlR1, Fen1, or Scc1 leads to defects in sister chromatid pairing.

Fig 8a. siRNA-mediated depletion of hChlR1, Fen1, or Scc1 leads to defects in sister chromatid pairing.
    Farina A, Shin JH, Kim DH, Bermudez VP, Kelman Z, Seo YS, Hurwitz J

  • J Biol Chem.
    2008 Jul 25;283(30):20925-36.

September 22, 2008

Fig 2. Structural homology between Clp1 and T4 Pnk.

Fig 2. Structural homology between Clp1 and T4 Pnk.
    Ramirez A, Shuman S, Schwer B

  • RNA.
    2008 Sep;14(9):1737-45.

September 19, 2008

Fig. 1. Transformation with plasmids carrying wild type (wt) human CHEK2, as well as the Y424H variant, represses the normally reduced viability due to Rad53 deletion in the Rad53-null sml1-null yeast S. cerevisiae.

Fig. 1. Transformation with plasmids carrying wild type (wt) human CHEK2, as well as the Y424H variant, represses the normally reduced viability due to Rad53 deletion in the Rad53-null sml1-null yeast S. cerevisiae.
    Tischkowitz MD, Yilmaz A, Chen LQ, Karyadi DM, Novak D, Kirchhoff T, Hamel N, Tavtigian SV, Kolb S, Bismar TA, Aloyz R, Nelson PS, Hood L, Narod SA, White KA, Ostrander EA, Isaacs WB, Offit K, Cooney KA, Stanford JL, Foulkes WD

  • Cancer Lett.
    2008 Oct 18;270(1):173-180.

September 18, 2008

Fig 2. Histologic examination of the tumor revealed discrete lobules of angiomatous tissue with inflammatory cells to the level of the muscular layer of the lower lip.

Fig 2. Histologic examination of the tumor revealed discrete lobules of angiomatous tissue with inflammatory cells to the level of the muscular layer of the lower lip.
    Wang SQ, Goldberg LH

  • Dermatol Surg.
    2008 Aug;34(8):1115-6.

September 17, 2008

Fig 1c. Immunocytochemistry for skeletal myosin heavy chain (MyHC) expression.

Fig 1c. Immunocytochemistry for skeletal myosin heavy chain (MyHC) expression.
    Seale P, Bjork B, Yang W, Kajimura S, Chin S, Kuang S, Scimè A, Devarakonda S, Conroe HM, Erdjument-Bromage H, Tempst P, Rudnicki MA, Beier DR, Spiegelman BM

  • Nature.
    2008 Aug 21;454(7207):961-7.

September 16, 2008

Fig 1c. Skin retracted with a long-stat retractor to avoid skin necrosis secondary to high-dose irradiation.

Fig 1c. Skin retracted with a long-stat retractor to avoid skin necrosis secondary to high-dose irradiation.
    Sacchini V, Beal K, Goldberg J, Montgomery L, Port E, McCormick B

  • Br J Surg.
    2008 Sep;95(9):1105-10.

September 15, 2008

Fig 1a. Structural alignment of the BRCT-related region in the T-ag helicase domain with the C-terminal BRCT repeat in 53BP1.

Fig 1a. Structural alignment of the BRCT-related region in the T-ag helicase domain with the C-terminal BRCT repeat in 53BP1.
    Kumar A, Joo WS, Meinke G, Moine S, Naumova EN, Bullock PA

  • J Virol.
    2008 Sep;82(17):8849-62.

September 12, 2008

Fig. 1b. Schematic representation of how to submit trachelectomy margin at the time of frozen-section analysis. Trachelectomy opened after shave showing grossly visible tumor; distance to margin is measured grossly.

Fig. 1b. Schematic representation of how to submit trachelectomy margin at the time of frozen-section analysis. Trachelectomy opened after shave showing grossly visible tumor; distance to margin is measured grossly.
    Park KJ, Soslow RA, Sonoda Y, Barakat RR, Abu-Rustum NR

  • Gynecol Oncol.
    2008 Sep;110(3):316-23.

September 11, 2008

Fig. 4c. Assessment of LLC Tumor Volume, Microvessel Density, Necrosis, and Long-Term Tumor Growth in Mice Treated with Paclitaxel or Gemcitabine in Combination with DC101C57BL/6 mice bearing 500 mm3 LLC tumors were treated with paclitaxel (PTX) or gemcitabine (GEM) with or without DC101 administered 24 hr prior to the chemotherapy drug.

Fig. 4c. Assessment of LLC Tumor Volume, Microvessel Density, Necrosis, and Long-Term Tumor Growth in Mice Treated with Paclitaxel or Gemcitabine in Combination with DC101C57BL/6 mice bearing 500 mm3 LLC tumors were treated with paclitaxel (PTX) or gemcitabine (GEM) with or without DC101 administered 24 hr prior to the chemotherapy drug.
    Shaked Y, Henke E, Roodhart JM, Mancuso P, Langenberg MH, Colleoni M, Daenen LG, Man S, Xu P, Emmenegger U, Tang T, Zhu Z, Witte L, Strieter RM, Bertolini F, Voest EE, Benezra R, Kerbel RS

  • Cancer Cell.
    2008 Sep 9;14(3):263-73.

September 10, 2008

Fig 4. Photograph and {gamma}-camera image of 4-quadrant bar phantom, Energy spectrum for 662-keV {gamma}-ray emitted by 137Cs.

Fig 4. Photograph and {gamma}-camera image of 4-quadrant bar phantom, Energy spectrum for 662-keV {gamma}-ray emitted by 137Cs.
    Zanzonico P

  • J Nucl Med.
    2008 Jul;49(7):1114-31.

September 9, 2008

Fig 7c. Direct intratumoral injection of si-SV1 induces apoptosis and reduces tumor growth in vivo.

Fig 7c. Direct intratumoral injection of si-SV1 induces apoptosis and reduces tumor growth in vivo.
    Narla G, DiFeo A, Fernandez Y, Dhanasekaran S, Huang F, Sangodkar J, Hod E, Leake D, Friedman SL, Hall SJ, Chinnaiyan AM, Gerald WL, Rubin MA, Martignetti JA

  • J Clin Invest.
    2008 Aug;118(8):2711-21.

September 8, 2008

Fig 8. Confirmation of novel gains on chromosomes 7q22 and
1q21.2 using fluorescence in situ hybridization (FISH).

Fig 8. Confirmation of novel gains on chromosomes 7q22 and 1q21.2 using fluorescence in situ hybridization (FISH).
    Antonescu CR, Wu K, Guoliang LX, Cao M, Turpaz Y, Leversha MA, Hubbell E, Maki RG, Miyada CG, Pillai R

  • Cancer Inform.
    2008 Mar 27;6: 59-75.

September 5, 2008

Fig. 1. Histologic appearance of pediatric GIST.

Fig. 1. Histologic appearance of pediatric GIST.
    Agaram NP, Laquaglia MP, Ustun B, Guo T, Wong GC, Socci ND, Maki RG, DeMatteo RP, Besmer P, Antonescu CR

  • Clin Cancer Res.
    2008 May 15;14(10):3204-15.

September 4, 2008

Fig. 6c COX-2 expression is upregulated in the SCDH of NR1 KO (Cre) mice.

Fig. 6c COX-2 expression is upregulated in the SCDH of NR1 KO (Cre) mice.
    Cheng HT, Suzuki M, Hegarty DM, Xu Q, Weyerbacher AR, South SM, Ohata M, Inturrisi CE

  • Neuroscience.
    2008 Aug 26;155(3):948-58.

September 2, 2008

Fig. 6E 2-year-old boy who presented with hoarseness and difficulty swallowing.

Fig. 6E 2-year-old boy who presented with hoarseness and difficulty swallowing.
    D'Ambrosio N, Soohoo S, Warshall C, Johnson A, Karimi S

  • AJR Am J Roentgenol.
    2008 Aug;191(2):589-97.

Content editor, Sarah Jewell
Last revised: September 30, 2008 4:21 PM EST
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