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Home Today's science sparks archives
 Today's science sparks archives - July to September 2009

Today's science sparks archives - July to September 2009

This page contains images and links to articles previously featured.

September 30, 2009

Fig 6. A model for the function of Drg1 in the regulation of Bim protein stability.

Fig 6. A model for the function of Drg1 in the regulation of Bim protein stability.

  • Ambrosini G, Seelman SL, Schwartz GK
  • Cancer Res.
    2009 Aug 1;69(15):6115-21.

September 29, 2009

Fig 4. Scatter plot of pixel Ktrans values obtained from single-image slice pharmacokinetic modeling analyses of a patient's DCE-MRI data.

Fig 4. Scatter plot of pixel Ktrans values obtained from single-image slice pharmacokinetic modeling analyses of a patient's DCE-MRI data.

  • Shukla-Dave A, Lee N, Stambuk H, Wang Y, Huang W, Thaler HT, Patel SG, Shah JP, Koutcher JA
  • BMC Med Phys.
    2009 Apr 7;9:4.

September 28, 2009

Fig 5. Transition structures for the reaction of vinylindene 1b with 1,4-quinone monoketal 2a without catalyst (top) and with TiCl4 (bottom).

Fig 5. Transition structures for the reaction of vinylindene 1b with 1,4-quinone monoketal 2a without catalyst (top) and with TiCl4 (bottom).

  • Hayden AE, DeChancie J, George AH, Dai M, Yu M, Danishefsky SJ, Houk KN
  • J Org Chem.
    2009 Sep 4;74(17):6770-6.

September 25, 2009

Fig 1. Manhattan plot of the P values in the pancreatic cancer GWAS.

Fig 1. Manhattan plot of the P values in the pancreatic cancer GWAS.

  • Amundadottir L, Kraft P, Stolzenberg-Solomon RZ, Fuchs CS, Petersen GM, Arslan AA, Bueno-de-Mesquita HB, Gross M, Helzlsouer K, Jacobs EJ, LaCroix A, Zheng W, Albanes D, Bamlet W, Berg CD, Berrino F, Bingham S, Buring JE, Bracci PM, Canzian F, Clavel-Chapelon F, Clipp S, Cotterchio M, de Andrade M, Duell EJ, Fox JW Jr, Gallinger S, Gaziano JM, Giovannucci EL, Goggins M, González CA, Hallmans G, Hankinson SE, Hassan M, Holly EA, Hunter DJ, Hutchinson A, Jackson R, Jacobs KB, Jenab M, Kaaks R, Klein AP, Kooperberg C, Kurtz RC, Li D, Lynch SM, Mandelson M, McWilliams RR, Mendelsohn JB, Michaud DS, Olson SH, Overvad K, Patel AV, Peeters PH, Rajkovic A, Riboli E, Risch HA, Shu XO, Thomas G, Tobias GS, Trichopoulos D, Van Den Eeden SK, Virtamo J, Wactawski-Wende J, Wolpin BM, Yu H, Yu K, Zeleniuch-Jacquotte A, Chanock SJ, Hartge P, Hoover RN
  • Nat Genet.
    2009 Sep;41(9):986-90.

September 24, 2009

MRI/MRSI findings and molecular markers correlated well with each other and contributed incremental value to clinical variables in predicting prostate cancer recurrence.

MRI/MRSI findings and molecular markers correlated well with each other and contributed incremental value to clinical variables in predicting prostate cancer recurrence.

  • Shukla-Dave A, Hricak H, Ishill N, Moskowitz CS, Drobnjak M, Reuter VE, Zakian KL, Scardino PT, Cordon-Cardo C
  • Clin Cancer Res.
    2009 Jun 1;15(11):3842-9.

September 23, 2009

Fig 1. CT scan of the pelvis (October 2004), showing a ring enhancing lesion of the right ovary.

Fig 1. CT scan of the pelvis (October 2004), showing a ring enhancing lesion of the right ovary.

  • Schiavon G, Maki R, Fornier M
  • Curr Cancer Ther Rev.
    2009 May; 5(2):100-04.

September 22, 2009

Fig 1. Cone Precursor Markers in Developing Retina and Retinoblastoma Tumors. (A–D) Photoreceptor precursor markers (red) and Rb (green) in gestational week 16 human retina.

Fig 1. Cone Precursor Markers in Developing Retina and Retinoblastoma Tumors. (A–D) Photoreceptor precursor markers (red) and Rb (green) in gestational week 16 human retina.

  • Xu XL, Fang Y, Lee TC, Forrest D, Gregory-Evans C, Almeida D, Liu A, Jhanwar SC, Abramson DH, Cobrinik D
  • Cell.
    2009 Jun 12;137(6):1018-31.

September 21, 2009

Fig 1. BM cells are recruited at the periphery of pulmonary metastatic lesions.

Fig 1. BM cells are recruited at the periphery of pulmonary metastatic lesions.

  • Gao D, Nolan D, McDonnell K, Vahdat L, Benezra R, Altorki N, Mittal V
  • Biochim Biophys Acta.
    2009 Aug;1796(1):33-40.

September 18, 2009

Fig. 5 Scratch-induced migration of primary rat astrocytes.

Fig. 5 Scratch-induced migration of primary rat astrocytes.

  • Hall A
  • Cancer Metastasis Rev.
    2009 Jun;28(1-2):5-14.

September 16, 2009

Figure 5. NF1 Genomic Alterations and Drug Sensitivity in Glioblastomas.

Figure 5. NF1 Genomic Alterations and Drug Sensitivity in Glioblastomas.

  • McGillicuddy LT, Fromm JA, Hollstein PE, Kubek S, Beroukhim R, De Raedt T, Johnson BW, Williams SM, Nghiemphu P, Liau LM, Cloughesy TF, Mischel PS, Parret A, Seiler J, Moldenhauer G, Scheffzek K, Stemmer-Rachamimov AO, Sawyers CL, Brennan C, Messiaen L, Mellinghoff IK, Cichowski K

  • Cancer Cell.
    2009 Jul 7;16(1):44-54.

September 15, 2009

Fig 2. E-cadherin trafficking in Drosophila. (A) E-cadherin (green) is located at the cell surface in the wild-type Drosophila pupal notum.

Fig 2. E-cadherin trafficking in Drosophila. (A) E-cadherin (green) is located at the cell surface in the wild-type Drosophila pupal notum.

  • Wirtz-Peitz F, Zallen JA

  • Curr Opin Genet Dev.
    2009 Aug;19(4):350-6.

September 14, 2009

Fig 2. Simple example of protein phosphorylation catalyzed by an enzyme and modulated by an inhibitor.

Fig 2. Simple example of protein phosphorylation catalyzed by an enzyme and modulated by an inhibitor.

  • Le Novère N, Hucka M, Mi H, Moodie S, Schreiber F, Sorokin A, Demir E, Wegner K, Aladjem MI, Wimalaratne SM, Bergman FT, Gauges R, Ghazal P, Kawaji H, Li L, Matsuoka Y, Villéger A, Boyd SE, Calzone L, Courtot M, Dogrusoz U, Freeman TC, Funahashi A, Ghosh S, Jouraku A, Kim S, Kolpakov F, Luna A, Sahle S, Schmidt E, Watterson S, Wu G, Goryanin I, Kell DB, Sander C, Sauro H, Snoep JL, Kohn K, Kitano H

  • Nat Biotechnol.
    2009 Aug;27(8):735-41.

September 11, 2009

Fig 1. Demonstration of Hu133-specific T cells that have lytic activity and secrete IFN-?.

Fig 1. Demonstration of Hu133-specific T cells that have lytic activity and secrete IFN-?.

  • Roberts WK, Deluca IJ, Thomas A, Fak J, Williams T, Buckley N, Dousmanis AG, Posner JB, Darnell RB

  • J Clin Invest.
    2009 Jul;119(7):2042-51.

September 10, 2009

Fig 4. Robust expression of MET in ASPS patient samples, with evidence of phosphorylation (activation) of MET in at least some cases. (Courtesy of S. Pilotti.)

Fig 4. Robust expression of MET in ASPS patient samples, with evidence of phosphorylation (activation) of MET in at least some cases. (Courtesy of S. Pilotti.)

  • Pires de Camargo V, van de Rijn M, de Alava E, Madoz-Gúrpide J, Pilotti S, von Mehren M, Pedeutour F, Maki RG, Rutkowski P, Thomas DM

  • Semin Oncol.
    2009 Aug;36(4):358-71.

September 9, 2009

Fig 4. Overlay of red fluorescent carcinoembryonic antigen (CEA) antibody and green fluorescence protein (GFP) expression in OCUM-2MD3 cancer cells.

Fig 4. Overlay of red fluorescent carcinoembryonic antigen (CEA) antibody and green fluorescence protein (GFP) expression in OCUM-2MD3 cancer cells.

  • Fong SM, Lee MK, Adusumilli PS, Kelly KJ

  • Surgery.
    2009 Sep;146(3):498-505.

September 8, 2009

Fig 3. C3f peptide degradation ladder.

Fig 3. C3f peptide degradation ladder.

  • Villanueva J, Nazarian A, Lawlor K, Tempst P

  • Nat Protoc.
    2009;4(8):1167-83.

September 4, 2009

Fig 1. Androgen receptor reactivation in prostate cancer progression

Fig 1. Androgen receptor reactivation in prostate cancer progression

  • Knudsen KE, Scher HI

  • Clin Cancer Res.
    2009 Aug 1;15(15):4792-8.

September 3, 2009

Fig 4. Variation of the zero calibrator over an entire plate.

Fig 4. Variation of the zero calibrator over an entire plate.

  • Courtney JB, Harney R, Li Y, Lundell G, McMillin GA, Agarwal G, Juenke JM, Mathew A, Gonzalez-Espinoza R, Fleisher M, Salamone SJ

  • Ther Drug Monit.
    2009 Aug;31(4):489-94.

September 2, 2009

Fig 1. The molecular mechanisms involved in the DNA damage response.

Fig 1. The molecular mechanisms involved in the DNA damage response.

  • Powell SN, Bindra RS

  • DNA Repair (Amst).
    2009 Sep 2;8(9):1153-65.

September 1, 2009

Fig 5a. Integrin-specific mTORC1 signaling promotes cell survival.

Fig 5a. Integrin-specific mTORC1 signaling promotes cell survival.

  • López-Lago MA, Okada T, Murillo MM, Socci N, Giancotti FG

  • Mol Cell Biol.
    2009 Aug;29(15):4235-49.

August 31, 2009

Fig 5a. Compared potency of the drug ouabain toward Y79 cells.

Fig 5a. Compared potency of the drug ouabain toward Y79 cells.

  • Antczak C, Kloepping C, Radu C, Genski T, Müller-Kuhrt L, Siems K, de Stanchina E, Abramson DH, Djaballah H

  • Invest Ophthalmol Vis Sci.
    2009 Jul;50(7):3065-73.

August 28, 2009

Fig 1. shRNA Screening Strategies: Well-by-Well versus Pooled Libraries.

Fig 1. shRNA Screening Strategies: Well-by-Well versus Pooled Libraries.

  • Sawyers CL

  • Cell.
    2009 May 29;137(5):796-8.

August 27, 2009

Fig 1b. Copy number analysis in CRCs using SNP arrays. One sample showed a more focused gain from 8q24.13 to 8q24.3.

Fig 1b. Copy number analysis in CRCs using SNP arrays. One sample showed a more focused gain from 8q24.13 to 8q24.3.

  • Tuupanen S, Turunen M, Lehtonen R, Hallikas O, Vanharanta S, Kivioja T, Björklund M, Wei G, Yan J, Niittymäki I, Mecklin JP, Järvinen H, Ristimäki A, Di-Bernardo M, East P, Carvajal-Carmona L, Houlston RS, Tomlinson I, Palin K, Ukkonen E, Karhu A, Taipale J, Aaltonen LA

  • Nat Genet.
    2009 Aug;41(8):885-90.

August 26, 2009

An International Journal for Cancer Care.

An International Journal for Cancer Care.

  • Brown RF, Bylund CL, Kline N, De La Cruz A, Solan J, Kelvin J, Gueguen J, Eddington J, Kissane D, Passik S

  • Cancer Nurs.
    2009 May-Jun;32(3):E1-7

August 25, 2009

Fig 1. Thymic function decreases with age. (d) Islands of cortical and medullary tissue in aged thymus show signs of active thymopoiesis by CD1a and Ki67 immunostain.

Fig 1. Thymic function decreases with age. (d) Islands of cortical and medullary tissue in aged thymus show signs of active thymopoiesis by CD1a and Ki67 immunostain.

  • Lynch HE, Goldberg GL, Chidgey A, Van den Brink MR, Boyd R, Sempowski GD

  • Trends Immunol.
    2009 Jul;30(7):366-73.

August 24, 2009

Fig 1. Leiomyosarcoma samples with differentiation scores of 1 to 3.

Fig 1. Leiomyosarcoma samples with differentiation scores of 1 to 3.

  • Collini P, Sorensen PH, Patel S, Blay JY, Issels RD, Maki RG, Eriksson M, Del Muro XG

  • Semin Oncol.
    2009 Aug;36(4):324-37.

August 21, 2009

Fig 9a. Stacking between different layers in the human telomeric G-quadruplex Form 3 in K+ solution. View from the side looking into the medium groove 1 (M1).

Fig 9a. Stacking between different layers in the human telomeric G-quadruplex Form 3 in K+ solution. View from the side looking into the medium groove 1 (M1).

  • Lim KW, Amrane S, Bouaziz S, Xu W, Mu Y, Patel DJ, Luu KN, Phan AT

  • J Am Chem Soc.
    2009 Apr 1;131(12):4301-9.

August 20, 2009

Fig 3. Plot of best radiological outcome by Response Evaluation Criteria in Solid Tumors (RECIST) by subject.

Fig 3. Plot of best radiological outcome by Response Evaluation Criteria in Solid Tumors (RECIST) by subject.

  • Maki RG, D'Adamo DR, Keohan ML, Saulle M, Schuetze SM, Undevia SD, Livingston MB, Cooney MM, Hensley ML, Mita MM, Takimoto CH, Kraft AS, Elias AD, Brockstein B, Blachère NE, Edgar MA, Schwartz LH, Qin LX, Antonescu CR, Schwartz GK

  • J Clin Oncol.
    2009 Jul 1;27(19):3133-40.

August 19, 2009

Fig 1. Prostatic core from TMA showing strong nuclear staining on immunochemistry for p53.

Fig 1. Prostatic core from TMA showing strong nuclear staining on immunochemistry for p53.

  • Kudahetti S, Fisher G, Ambroisine L, Foster C, Reuter V, Eastham J, Møller H, Kattan MW, Cooper CS, Scardino P, Cuzick J, Berney DM

  • BJU Int.
    2009 Jul;104(1):20-4.

August 18, 2009

Fig 2j. H2030 parental and H2030-BrM3 cells were implanted with Matrigel in the lung via intrathoracic inoculation.

Fig 2j. H2030 parental and H2030-BrM3 cells were implanted with Matrigel in the lung via intrathoracic inoculation.

  • Nguyen DX, Chiang AC, Zhang XH, Kim JY, Kris MG, Ladanyi M, Gerald WL, Massagué J

  • Cell.
    2009 Jul 10;138(1):51-62.

August 17, 2009

Fig 4. Comparison of a right lateral beam's-eye view as seen in the planning scan and a CBCT scan.

Fig 4. Comparison of a right lateral beam's-eye view as seen in the planning scan and a CBCT scan.

  • Mechalakos J, Lee N, Hunt M, Ling CC, Amols HI

  • Med Dosim.
    2009 Fall;34(3):250-5.

August 13, 2009

Fig 2. A 90-year-old woman underwent PET/CT for initial staging of non-small-cell lung carcinoma and for guiding radiation therapy planning.

Fig 2. A 90-year-old woman underwent PET/CT for initial staging of non-small-cell lung carcinoma and for guiding radiation therapy planning.

  • Delbeke D, Schöder H, Martin WH, Wahl RL

  • Semin Nucl Med.
    2009 Sep;39(5):308-40.

August 12, 2009

Fig 6. Electron microscopic evaluation of morphology of polymer formed in glutamate without GTP.

Fig 6. Electron microscopic evaluation of morphology of polymer formed in glutamate without GTP.

  • Edler MC, Yang G, Katherine Jung M, Bai R, Bornmann WG, Hamel E

  • Arch Biochem Biophys.
    2009 Jul 15;487(2):98-104.

August 11, 2009

Fig 1. HnRNP-L is a novel subunit of the human KMT3a complex. A, domain structure of human KMT3a and yeast KMT3.

Fig 1. HnRNP-L is a novel subunit of the human KMT3a complex. A, domain structure of human KMT3a and yeast KMT3.

  • Yuan W, Xie J, Long C, Erdjument-Bromage H, Ding X, Zheng Y, Tempst P, Chen S, Zhu B, Reinberg D

  • J Biol Chem.
    2009 Jun 5;284(23):15701-7.

August 10, 2009

Fig 9. A Model that Illustrates mPar3 Regulation of Notch Signaling and Asymmetric Cell Division of Radial Glial Cells in the Developing Neocortex.

Fig 9. A Model that Illustrates mPar3 Regulation of Notch Signaling and Asymmetric Cell Division of Radial Glial Cells in the Developing Neocortex.

  • Bultje RS, Castaneda-Castellanos DR, Jan LY, Jan YN, Kriegstein AR, Shi SH

  • Neuron.
    2009 Jul 30;63(2):189-202.

August 7, 2009

Fig 1c. Nontransgenic primary mammary cells grown in 3D cultures develop acini composed of polarized epithelial cells.

Fig 1c. Nontransgenic primary mammary cells grown in 3D cultures develop acini composed of polarized epithelial cells.

  • Jechlinger M, Podsypanina K, Varmus H

  • Genes Dev.
    2009 Jul 15;23(14):1677-88.

August 6, 2009

Fig 6. YK-4-279 inhibits the growth of ESFT xenograft tumors.

Fig 6. YK-4-279 inhibits the growth of ESFT xenograft tumors.

  • Erkizan HV, Kong Y, Merchant M, Schlottmann S, Barber-Rotenberg JS, Yuan L, Abaan OD, Chou TH, Dakshanamurthy S, Brown ML, Uren A, Toretsky JA

  • Nat Med.
    2009 Jul;15(7):750-6.

August 5, 2009

Fig 12. Molecular architecture of Gal4BD-Spo11.

Fig 12. Molecular architecture of Gal4BD-Spo11.

  • Murakami H, Nicolas A

  • Mol Cell Biol.
    2009 Jul;29(13):3500-16.

August 4, 2009

Fig 2. DNA ligases engage the nicked duplex as C-shaped protein clamps.

Fig 2. DNA ligases engage the nicked duplex as C-shaped protein clamps.

  • Shuman S

  • J Biol Chem.
    2009 Jun 26;284(26):17365-9.

August 3, 2009

Fig 6. ART-27 expression and clinical outcome in AR-positive prostate cancer. A, ART-27 exhibits differential subcellular expression profiles in AR-positive prostate cancer.

Fig 6. ART-27 expression and clinical outcome in AR-positive prostate cancer. A, ART-27 exhibits differential subcellular expression profiles in AR-positive prostate cancer.

  • Nwachukwu JC, Mita P, Ruoff R, Ha S, Wang Q, Huang SJ, Taneja SS, Brown M, Gerald WL, Garabedian MJ, Logan SK

  • Cancer Res.
    2009 Apr 1;69(7):3140-7.

July 31, 2009

FIG 6. Tryptophan 96 and neighboring residues in the GLTP·N-oleoyl LacCer complex.

FIG 6. Tryptophan 96 and neighboring residues in the GLTP·N-oleoyl LacCer complex.

  • Zhai X, Malakhova ML, Pike HM, Benson LM, Bergen HR 3rd, Sugár IP, Malinina L, Patel DJ, Brown RE

  • J Biol Chem.
    2009 May 15;284(20):13620-8.

July 30, 2009

Fig 2f. Neoplastic melanocytes are highlighted with aid of A103 immunostain.

Fig 2f. Neoplastic melanocytes are highlighted with aid of A103 immunostain.

  • Braga JC, Scope A, Klaz I, Mecca P, González S, Rabinovitz H, Marghoob AA

  • J Am Acad Dermatol.
    2009 Aug;61(2):230-41.

July 29, 2009

Fig 1. Dual-modality imaging using hNET and HSV1-tk reporter genes for monitoring different populations of antigen-specific CTLs.

Fig 1. Dual-modality imaging using hNET and HSV1-tk reporter genes for monitoring different populations of antigen-specific CTLs.

  • Ponomarev V

  • J Nucl Med.
    2009 Jun 12.

July 28, 2009

Fig 6. H&E staining of splenic lymphoma tissue in a p53 KO mouse and a p53/Elf4 DKO mouse, together with representative staining of Mdm2 and p16 protein by IHC.

Fig 6. H&E staining of splenic lymphoma tissue in a p53 KO mouse and a p53/Elf4 DKO mouse, together with representative staining of Mdm2 and p16 protein by IHC.

  • Sashida G, Liu Y, Elf S, Miyata Y, Ohyashiki K, Izumi M, Menendez S, Nimer SD

  • Mol Cell Biol.
    2009 Jul;29(13):3687-99.

July 27, 2009

Fig 1c. Induction of chromosomal translocations in TOS4A cells.

Fig 1c. Induction of chromosomal translocations in TOS4A cells.

  • Brunet E, Simsek D, Tomishima M, DeKelver R, Choi VM, Gregory P, Urnov F, Weinstock DM, Jasin M

  • Proc Natl Acad Sci U S A.
    2009 Jun 30;106(26):10620-5.

July 24, 2009

Fig 2a. Conserved amino acids targeted for alanine scanning in S. pombe Spt4. Location of targeted residues in the Spt4 tertiary structure.

Fig 2a. Conserved amino acids targeted for alanine scanning in S. pombe Spt4. Location of targeted residues in the Spt4 tertiary structure.

  • Schwer B, Schneider S, Pei Y, Aronova A, Shuman S

  • RNA.
    2009 Jul;15(7):1241-50.

July 23, 2009

Fig 4h. Src Enhances Metastasis Survival and Outgrowth in Bone Marrow. Representative TRAP staining. Arrows indicate positive staining.

Fig 4h. Src Enhances Metastasis Survival and Outgrowth in Bone Marrow. Representative TRAP staining. Arrows indicate positive staining.

  • Zhang XH, Wang Q, Gerald W, Hudis CA, Norton L, Smid M, Foekens JA, Massagué J

  • Cancer Cell.
    2009 Jul 7;16(1):67-78.

July 22, 2009

Fig 1. Isolation and characterization of brain metastatic variants. i, GPF+ MDA231-BrM2a cells (arrowheads) arrested in brain capillaries (red, rhodamine dextran) 24 h after intracardiac injection into mice.

Fig 1. Isolation and characterization of brain metastatic variants. i, GPF+ MDA231-BrM2a cells (arrowheads) arrested in brain capillaries (red, rhodamine dextran) 24 h after intracardiac injection into mice.

  • Bos PD, Zhang XH, Nadal C, Shu W, Gomis RR, Nguyen DX, Minn AJ, van de Vijver MJ, Gerald WL, Foekens JA, Massagué J

  • Nature.
    2009 Jun 18;459(7249):1005-9.

July 21, 2009

Fig 4. (A–L) Immunostaining of cytospins containing mononuclear cells from BM aspirates pulled from children with NB stage M.

Fig 4. (A–L) Immunostaining of cytospins containing mononuclear cells from BM aspirates pulled from children with NB stage M.

  • Beiske K, Burchill SA, Cheung IY, Hiyama E, Seeger RC, Cohn SL, Pearson AD, Matthay KK; International neuroblastoma Risk Group Task Force

  • Br J Cancer.
    2009 May 19;100(10):1627-37.

July 20, 2009

Fig 6a. Immunofluorescence microscopy analysis of cDO subcellular localization.

Fig 6a. Immunofluorescence microscopy analysis of cDO subcellular localization.

  • Deshaies F, Diallo DA, Fortin JS, O'Rourke HM, Pezeshki AM, Bellemare-Pelletier A, Raby N, Bédard N, Brunet A, Denzin LK, Thibodeau J

  • Immunology.
    2009 Jul;127(3):408-17.

July 17, 2009

Fig 3a. Expression matrix of 6 genes belonging to the oxidative phosphorylation pathway, which were downregulated in poor outcome tumors.

Fig 3a. Expression matrix of 6 genes belonging to the oxidative phosphorylation pathway, which were downregulated in poor outcome tumors.

  • Sheffer M, Bacolod MD, Zuk O, Giardina SF, Pincas H, Barany F, Paty PB, Gerald WL, Notterman DA, Domany E

  • Proc Natl Acad Sci U S A.
    2009 Apr 28;106(17):7131-6.

July 16, 2009

Fig 3c. Immunofluorescence of Pax3:Fkhr during disease progression (400x).

Fig 3c. Immunofluorescence of Pax3:Fkhr during disease progression (400x).

  • Nishijo K, Chen QR, Zhang L, McCleish AT, Rodriguez A, Cho MJ, Prajapati SI, Gelfond JA, Chisholm GB, Michalek JE, Aronow BJ, Barr FG, Randall RL, Ladanyi M, Qualman SJ, Rubin BP, LeGallo RD, Wang C, Khan J, Keller C

  • Cancer Res.
    2009 Apr 1;69(7):2902-11.

July 15, 2009

Fig 1. Tie2/GFP expression by endothelial cells as visualized by multiphoton fluorescence microscopy.

Fig 1. Tie2/GFP expression by endothelial cells as visualized by multiphoton fluorescence microscopy.

  • Dunphy MP, Entenberg D, Toledo-Crow R, Larson SM

  • Microvasc Res.
    2009 Jun;78(1):51-6.

July 14, 2009

Fig 4. Reciprocal changes in immunohistochemical CPI and cathepsin B staining in MV generated 4 d after s.c. injection of 106 TA3/St mammary carcinoma cells.

Fig 4. Reciprocal changes in immunohistochemical CPI and cathepsin B staining in MV generated 4 d after s.c. injection of 106 TA3/St mammary carcinoma cells.

  • Chang SH, Kanasaki K, Gocheva V, Blum G, Harper J, Moses MA, Shih SC, Nagy JA, Joyce J, Bogyo M, Kalluri R, Dvorak HF

  • Cancer Res.
    2009 May 15;69(10):4537-44.

July 13, 2009

Fig 5. Anti-tumor effects of PU-H71 are associated with down-regulation of several Hsp90-regulated malignancy driving proteins.

Fig 5. Anti-tumor effects of PU-H71 are associated with down-regulation of several Hsp90-regulated malignancy driving proteins.

  • Caldas-Lopes E, Cerchietti L, Ahn JH, Clement CC, Robles AI, Rodina A, Moulick K, Taldone T, Gozman A, Guo Y, Wu N, de Stanchina E, White J, Gross SS, Ma Y, Varticovski L, Melnick A, Chiosis G

  • Proc Natl Acad Sci U S A.
    2009 May 19;106(20):8368-73.

July 10, 2009

Fig 1. The lambda epigenetic switch: the Cro gene is transcribed but the repressor gene (cI) is not. An early stage of lytic growth of the phage is shown.

Fig 1. The lambda epigenetic switch: the Cro gene is transcribed but the repressor gene (cI) is not. An early stage of lytic growth of the phage is shown.

  • Ptashne M

  • Curr Biol.
    2009 Mar 24;19(6):R234-41.

July 9, 2009

Fig 3. Waterfall graphs of prostate-specific antigen (PSA) response by cohort.

Fig 3. Waterfall graphs of prostate-specific antigen (PSA) response by cohort.

  • Morris MJ, Pandit-Taskar N, Carrasquillo J, Divgi CR, Slovin S, Kelly WK, Rathkopf D, Gignac GA, Solit D, Schwartz L, Stephenson RD, Hong C, Delacruz A, Curley T, Heller G, Jia X, O'Donoghue J, Larson S, Scher HI

  • J Clin Oncol.
    2009 May 20;27(15):2436-42.

July 8, 2009

Fig 2. TGF-ß induces the expression of NF-B in prostate cancer.

Fig 2. TGF-ß induces the expression of NF-B in prostate cancer.

  • Zhang Q, Helfand BT, Jang TL, Zhu LJ, Chen L, Yang XJ, Kozlowski J, Smith N, Kundu SD, Yang G, Raji AA, Javonovic B, Pins M, Lindholm P, Guo Y, Catalona WJ, Lee C

  • Clin Cancer.
    2009 May 15;15(10):3557-67.

July 7, 2009

Fig 3. miR-26a-expressing murine gliomas (P/26a). (A) Schematic of RCAS-miR constructs; CMV denotes CMV promoter, GFP denotes GFP cassette, and miR denotes miRNA domain.

Fig 3. miR-26a-expressing murine gliomas (P/26a). (A) Schematic of RCAS-miR constructs; CMV denotes CMV promoter, GFP denotes GFP cassette, and miR denotes miRNA domain.

  • Huse JT, Brennan C, Hambardzumyan D, Wee B, Pena J, Rouhanifard SH, Sohn-Lee C, le Sage C, Agami R, Tuschl T, Holland EC

  • Genes Dev.
    2009 Jun 1;23(11):1327-37.

July 6, 2009

Fig 2. Annual Age-adjusted Cancer Incidence and Death Rates for All Sites by Sex, United States, 1975–2005.

Fig 2. Annual Age-adjusted Cancer Incidence and Death Rates for All Sites by Sex, United States, 1975–2005.

  • Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ

  • CA Cancer J Clin.
    2009 Jun 25.

July 2, 2009

Fig 2. Akt-1 expressions in breast cell line MCF-7.

Fig 2. Akt-1 expressions in breast cell line MCF-7.

  • Li R, Dai H, Wheeler TM, Sayeeduddin M, Scardino PT, Frolov A, Ayala GE

  • Clin Cancer Res.
    2009 May 15;15(10):3568-73.

July 1, 2009

Fig 1. Regulation of Foxp3 expression.

Fig 1. Regulation of Foxp3 expression.

  • Lu LF, Rudensky A

  • Genes Dev.
    2009 Jun 1;23(11):1270-82.
Content editor, Sarah Jewell
Last revised: October 1, 2009 8:44 AMST
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