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The National Library of Medicine recently announced a new funding opportunity, seeking applications for novel informatics and data science approaches that can help individuals gather, manage and use information regarding their personal health.

While patients typically discuss their personal health decisions with the clinicians from whom they receive care, they also seek health information from sources that are increasingly digital and constantly changing. For instance, health-related information can come from diverse sources, such as mass media and social networks, health care organizations, government agencies, clinicians, family members and friends. It can also comes in many different formats, such as data from an individual’s electronic medical record, family histories and genealogies, data streams from activity trackers, personal genome sequences, articles and videos, etc.

New approaches are needed to meet the needs of consumers and patients, whose health literacy, language skills, technical sophistication, education and cultural traditions may affect how they find, understand and use the information. Applicants may propose new tools or extensions to the capabilities of existing open source tools. In either case, scientific innovation is key.

Applications are due by 5:00 pm on May 1, 2017. For more information, see PAR-17-159.

The 2017 MPN Challenge is a grant program from the MPN Research Foundation that aims to change the trajectory and prognosis for patients with myeloproliferative neoplasms.

Myeloproliferative neoplasms (MPNs) are a closely related group of blood cancers that occur when the bone marrow overproduces one of the mature blood elements. While the discovery of JAK2 inhibitors has led to significant improvements in patient care, new approaches are sought in order to better understand and control the progression of MPNs from chronic to life-threatening stages.

This year’s challenge focuses on the elimination of the mutant stem cells which promote the diseases. In addition to the 3 topic areas indicated (eliminating the mutant stem cell directly, eliminating the mutant stem cell indirectly, disrupting the microenvironment), proposals aimed at more clearly understanding the pathogenesis and progression of MPNs will also be reviewed.

Proposals will be accepted starting February 1, 2017 and are due on April 1, 2017. For more information and instructions, see the 2017 MPN Challenge website.